[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599690":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":22,"centralContacts":31,"locations":37,"responsibleParty":56,"collaborators":22,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":22,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":22,"enrollmentInfo":68,"targetDuration":22,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":22,"overallStatus":40,"whyStopped":22,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"The University of Texas Medical Branch, Galveston","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Gait Training with Combined Sensory Feedback and Mechanical Constraints","EXPERIMENTAL","All participants will receive various gait training conditions during a single session. Conditions include treadmill walking (tied-belt and split-belt), backward-directed resistance (applied at pelvis, ankle, or both), sensory feedback (visual, auditory, or combined), and a final combined condition integrating both resistance and feedback. This is a within-subject crossover design.",[13,14,15],"Behavioral: Treadmill Walking with Split-Belt and\u002For Tied-Belt Conditions","Behavioral: Mechanical Resistance (Pelvis and\u002For Ankle) depending on participant's walking capacity","Behavioral: Sensory Feedback Training",[17,23,27],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"BEHAVIORAL","Treadmill Walking with Split-Belt and\u002For Tied-Belt Conditions","Participants will walk on an instrumented treadmill under split-belt and\u002For tied-belt conditions depending on their walking capacity. The belt speeds will be adjusted to facilitate locomotor adaptation and evaluate propulsion symmetry.",[9],null,{"type":18,"name":24,"description":25,"armGroupLabels":26,"otherNames":22},"Mechanical Resistance (Pelvis and\u002For Ankle) depending on participant's walking capacity","Participants will walk on a treadmill (Split-belt and\u002For Tied-belt) with backward-directed resistance applied at the pelvis, ankle, or both. The resistance is used to challenge paretic leg propulsion and assess adaptive gait responses.",[9],{"type":18,"name":28,"description":29,"armGroupLabels":30,"otherNames":22},"Sensory Feedback Training","Real-time feedback-visual, auditory, or combined-will be provided based on the propulsive force generated during split-belt and\u002For tied-belt treadmill walking, with or without mechanical resistance.",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":22,"email":36},"Mansoo Ko, PhD","CONTACT","409-747-1617","mako@utmb.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"University of Texas Medical Branch","RECRUITING","Galveston","Texas","77555","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-94.7977,29.30135,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":55,"phoneExt":22,"email":36},"Mansoo Ko","409-772-9555",{"type":57,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100599690","optimizing-gait-symmetry-after-stroke-using-mechanical-constraints-and-sensory-feedback-100599690",false,"NCT07087769","Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback","Optimizing Post-Stroke Gait Symmetry: Integrating Mechanical Constraints and Sensory Feedback to Enhance Paretic Leg Propulsion","Inclusion Criteria:\n\nAged 20 years or older\n\nFor stroke group: clinical diagnosis of stroke at least 1 month prior to participation\n\nAbility to walk at least 10 meters with or without assistive devices\n\nFor healthy group: able to walk independently without assistive devices\n\nExclusion Criteria:\n\nLife expectancy less than one year\n\nComatose or unable to follow three-step commands\n\nAmputation of any lower limb\n\nPoorly controlled diabetes (e.g., foot ulceration)\n\nBlindness\n\nProgressive neurological disease\n\nMedically unstable condition\n\nSignificant musculoskeletal impairments affecting gait\n\nCongestive heart failure or unstable angina\n\nPeripheral vascular disease\n\nSevere neuropsychiatric conditions (e.g., dementia, cognitive deficits, severe depression)",true,"ALL","20 Years",{"count":69,"type":70},30,"ESTIMATED","INTERVENTIONAL",[73],"NA","This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy adults, each aged 20 years or older. Participants will walk on both tied-belt and split-belt treadmills under various training conditions, including backward-directed resistance (applied at the pelvis, ankle, or both) and real-time sensory feedback (visual, auditory, or combined). These interventions will be applied individually and in combination to identify the most effective environment for promoting symmetrical gait patterns. Each session will last approximately two hours. The equipment used is non-invasive, and the risk to participants is minimal.",[76,77,78,79,80],"Stroke","Split-belt Treadmill","Resistance Exercise","Feedback","Gait Training","2026-03-31",{"date":83,"type":84},"2026-04-01","ACTUAL",{"date":86,"type":84},"2025-07-25",{"date":88,"type":70},"2026-12-01",{"name":5,"class":6},1]