[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100500337":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":27,"responsibleParty":59,"collaborators":61,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":10,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Tromso","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Breastfeeding mothers",null,"In this study breastfeeding mothers will be included. Samples will be collected from breast-feeding mothers experiencing mastitis Samples will be collected from breast-feeding mothers after the mastitis episode is resolved Breastfeeding mothers will be sampled at each mastitis episode, and with the final sample collected after a maximum of 12 months",[13],{"name":14,"affiliation":15,"role":16},"Jorunn Pauline Cavanagh, PhD","The Arctic university of Norway-UiT","PRINCIPAL_INVESTIGATOR",[18,23],{"name":14,"role":19,"phone":20,"phoneExt":21,"email":22},"CONTACT","40498490","47","pauline.cavanagh@uit.no",{"name":24,"role":19,"phone":25,"phoneExt":21,"email":26},"Claus Klingenberg, MD, PhD","91563167","claus.klingengerg@unn.no",[28,42],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":10},"Tromsø municipality, health centre","RECRUITING","Tromsø","Troms","9019","Norway","NO",{"type":37,"coordinates":38},"Point",[39,40],18.95508,69.6489,{"lat":40,"lon":39},{"facility":43,"status":30,"city":31,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":44,"geoPoint":46,"contacts":47},"UiT-The Arctic University of Norway",{"type":37,"coordinates":45},[39,40],{"lat":40,"lon":39},[48,50,53,55,57],{"name":49,"role":19,"phone":10,"phoneExt":21,"email":22},"Pauline Cavanagh, PhD",{"name":51,"role":52,"phone":10,"phoneExt":10,"email":10},"Beate Fossum Løland, MD,PhD","SUB_INVESTIGATOR",{"name":54,"role":52,"phone":10,"phoneExt":10,"email":10},"Ina Landau Aasen, MAc",{"name":56,"role":52,"phone":10,"phoneExt":10,"email":10},"Hermoine Venter, PhD",{"name":58,"role":52,"phone":10,"phoneExt":10,"email":10},"Claus Klingenberg, MD,PhD",{"type":60,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[62,65,67],{"name":63,"class":64},"Norwegian Institute of Public Health","OTHER_GOV",{"name":66,"class":6},"The University of Western Australia",{"name":68,"class":69},"Helse Nord","INDUSTRY","100500337","optimizing-mastitis-identification-and-treatment-100500337",false,"NCT05794945","Optimizing Mastitis Identification and Treatment","OPTIMISTOptimizing Mastitis Identification and Treatment","OPTIMIST","Inclusion Criteria:\n\n* Pregnant mothers aged \\> 18\n* mothers must understand information given in Norwegian or English\n* participants must be willing to complete study questionnaires\n* participants must be willing to and provide biological samples\n\nExclusion Criteria:\n\n* No exclusion criteria","FEMALE","18 Years","50 Years",{"count":82,"type":83},300,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially concerning judicious use of antibiotics.\n\nThe main questions it aims to answer are:\n\n* Do clinical symptoms differ between inflammatory and infectious mastitis?\n* What is the microbial composition in human milk, and does it change before, during, and after episodes of mastitis?\n* Does the bacterial composition change due to antibiotic treatment?\n* Are all mastitis episodes treated with antibiotics bacterial mastitis?\n* Do mothers with recurrent mastitis have a distinct microbial composition?\n* Are there immunological markers that can differentiate between bacterial and inflammatory mastitis?\n\nResearchers will compare breastfeeding women with and without mastitis to see if the microbiological composition in milk and on the skin of the breast and breast nipple differs.",[87],"Mastitis Postpartum",[89,90,91],"Breast inflammation","Clinical mastitis","Sub-clinical mastitis","2026-03-11",{"date":94,"type":95},"2026-03-12","ACTUAL",{"date":97,"type":95},"2023-10-01",{"date":99,"type":83},"2028-10-01",{"name":5,"class":6},2]