[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573300":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":21,"locations":30,"responsibleParty":47,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":77,"overallStatus":84,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Toronto","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Children",null,"Children as defined by maturity offset via age from peak height velocity (aPHV \\\u003C -1.0 years).",{"label":13,"type":10,"description":14,"interventionNames":10},"Adolescent","Adolescents as defined by maturity offset via age from peak height velocity (aPHV -0.5 to +1.5 years)",{"label":16,"type":10,"description":17,"interventionNames":10},"Young Adults","Young adults as defined by chronological age between ages 18 - 35 years",{"label":19,"type":10,"description":20,"interventionNames":10},"Older Adults","Older adults as defined by chronological age between ages 60 - 80 years",[22,27],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Daniel R Moore, PhD","CONTACT","4169464088","dr.moore@utoronto.ca",{"name":28,"role":24,"phone":10,"phoneExt":10,"email":29},"Hugo JW Fung, PhD Candidate","hugojernwai.fung@utoronto.ca",[31],{"facility":32,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Goldring Center for High Performance Sport","Toronto","Ontario","M5S 2C9","Canada","CA",{"type":39,"coordinates":40},"Point",[41,42],-79.39864,43.70643,{"lat":42,"lon":41},[45],{"name":28,"role":24,"phone":46,"phoneExt":10,"email":29},"416-946-5620",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Daniel Moore","Professor, Muscle Physiology","100573300","oral-breath-test-to-measure-anabolic-sensitivity-to-a-protein-meal-across-the-age-and-physical-activity-spectrum-100573300",false,"NCT06744491","Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum","Anabolic Sensitivity Across the Lifespan","NFRF","Inclusion Criteria:\n\n* Healthy will be defined as screened by the PAR-Q+ (The Physical Activity Readiness Questionnaire for everyone)\n* Chronological age for Healthy Young (age: 18-35 years) or Older (age: 60-80 years) adults\n* Chronological age between 8 to 16 years, with maturity offset \\\u003C -1 year from age of Peak Height Velocity (aPHV) for children and between -0.5 to +1.5 years from aPHV in adolescent participants\n* BMI between normal to overweight (18.5 - 29.9 kg\u002Fm2)\n\nExclusion Criteria:\n\n* Regular use of nonsteroidal anti-inflammatory dugs (with the exception of daily low-dose aspirin)\n* use of anticoagulants\n* use of a walker, cane, or assistive walking device\n* infectious or gastrointestinal disease\n* inability to comply with study protocol (e.g., unable to track diet)\n* regular tobacco use\n* self-reported illicit drug use (e.g., growth hormone, testosterone, etc.)\n* diagnosed chronic illness (e.g., type 2 diabetes, heart disease, thyroid disease)\n* pregnant\n* hormonal replacement therapy",true,"ALL","8 Years","80 Years",{"count":64,"type":65},80,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.",[69,70,71,72,73,74,75,76],"Inactivity, Physical","Aging","Healthy Aging","Growth & Development","Sex Differences","Anabolic Sensitivity","Protein Metabolism","Physical Activity",[78,79,80,81,82,83],"anabolic sensitivity","aging","growth and development","physical activity","skeletal muscle","stable isotopes","NOT_YET_RECRUITING","2024-12-16",{"date":87,"type":88},"2024-12-20","ACTUAL",{"date":87,"type":65},{"date":91,"type":65},"2025-08-31",{"name":5,"class":6},1]