[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602916":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":37,"locations":45,"responsibleParty":121,"collaborators":124,"id":128,"slug":129,"hasResults":130,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":130,"sex":136,"minAge":137,"maxAge":18,"enrollmentInfo":138,"targetDuration":18,"studyType":141,"phases":142,"briefSummary":144,"conditions":145,"keywords":151,"overallStatus":156,"whyStopped":18,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":166},{"fullName":5,"class":6},"Hospital do Coracao","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral hygiene bundle","EXPERIMENTAL","This arm will receive the standardized oral hygiene bundle",[13],"Other: Oral hygiene bundle",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care","NO_INTERVENTION","Each center will maintain its usual oral care practices.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":18},"Implementation of the standardized oral hygiene bundle, which consists of the following key components: Standardization of materials used during the oral hygiene procedure, standardization of oral hygiene frequency, training of nursing staff involved in patient care on proper oral hygiene practices, discontinuation of routine application of chlorhexidine oral solution, and implementation of a standardized oral hygiene technique.",[9],[24,28,32,34],{"name":25,"affiliation":26,"role":27},"Fernando Belissimo-Rodrigues, MD, PhD","Faculdade de Medicina de Ribeirão Preto da USP","STUDY_CHAIR",{"name":29,"affiliation":30,"role":31},"Bruno M Tomazini, MD","Hospital do Coração (Hcor)","PRINCIPAL_INVESTIGATOR",{"name":33,"affiliation":26,"role":27},"Wanessa Belissimo-Rodrigues, PhD",{"name":35,"affiliation":30,"role":36},"Alexandre Biasi Cavalcanti, MD, PhD","STUDY_DIRECTOR",[38,42],{"name":29,"role":39,"phone":40,"phoneExt":18,"email":41},"CONTACT","+5511982839173","btomazini@hocr.com.br",{"name":33,"role":39,"phone":43,"phoneExt":18,"email":44},"+111699963-8236‬","wanessatbr@gmail.com",[46,61,73,85,97,109],{"facility":47,"status":18,"city":48,"state":49,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Santa Casa de Misericordia de Passos","Passos","Minas Gerais","Brazil","BR",{"type":53,"coordinates":54},"Point",[55,56],-46.60972,-20.71889,{"lat":56,"lon":55},[59],{"name":60,"role":39,"phone":18,"phoneExt":18,"email":18},"Priscila Goncalves",{"facility":62,"status":18,"city":63,"state":64,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Hospital Municipal de Maringa","Maringá","Paraná",{"type":53,"coordinates":66},[67,68],-51.93861,-23.42528,{"lat":68,"lon":67},[71],{"name":72,"role":39,"phone":18,"phoneExt":18,"email":18},"Francielle Pereira",{"facility":74,"status":18,"city":75,"state":76,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Hospital da Restauracao","Recife","Pernambuco",{"type":53,"coordinates":78},[79,80],-34.88111,-8.05389,{"lat":80,"lon":79},[83],{"name":84,"role":39,"phone":18,"phoneExt":18,"email":18},"Debora Pinho",{"facility":86,"status":18,"city":87,"state":88,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Hospital Santa Cruz","Santa Cruz","Rio Grande do Sul",{"type":53,"coordinates":90},[91,92],-53.1439,-27.335,{"lat":92,"lon":91},[95],{"name":96,"role":39,"phone":18,"phoneExt":18,"email":18},"Maite Magdalena",{"facility":98,"status":18,"city":99,"state":100,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Hospital Nereu Ramos","Florianópolis","Santa Catarina",{"type":53,"coordinates":102},[103,104],-48.54917,-27.59667,{"lat":104,"lon":103},[107],{"name":108,"role":39,"phone":18,"phoneExt":18,"email":18},"Israel S. Maia",{"facility":110,"status":18,"city":111,"state":112,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":113,"geoPoint":117,"contacts":118},"Hospital Leo Orsi","Itapetininga","São Paulo",{"type":53,"coordinates":114},[115,116],-48.05306,-23.59167,{"lat":116,"lon":115},[119],{"name":120,"role":39,"phone":18,"phoneExt":18,"email":18},"Vivian Irineu",{"type":31,"investigatorFullName":122,"investigatorTitle":123,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Bruno Martins Tomazini","MD",[125],{"name":126,"class":127},"Faculdade de Medicina de Ribeirão Preto\u002FUSP","UNKNOWN","100602916","oral-care-layered-enhancement-for-improved-oral-hygiene-in-intensive-care-units-100602916",false,"NCT07129733","Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units","Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units: A Stepped-Wedge Cluster Randomized Clinical Trial","ORACLE","Inclusion Criteria:\n\n* All patients who receive mechanical ventilation in the participating intensive care units\n\nExclusion Criteria:\n\n* Does not meet inclusion criteria","ALL","18 Years",{"count":139,"type":140},4800,"ESTIMATED","INTERVENTIONAL",[143],"NA","The goal of the ORACLE study is to evaluate the impact of implementing a standardized oral hygiene bundle on outcomes in critically ill, mechanically ventilated patients. The primary objective is to determine whether this bundle can increase the number of ventilator-free days compared to the standard of care.",[146,147,148,149,150],"Mechanical Ventilation","Infection Prevention","Oral Care","Oral Hygiene, Oral Health","VAP - Ventilator Associated Pneumonia",[152,153,154,155],"Oral care","Oral hygiene","critically ill","mechanical ventilation","NOT_YET_RECRUITING","2025-08-15",{"date":159,"type":160},"2025-08-19","ACTUAL",{"date":162,"type":140},"2025-09-01",{"date":164,"type":140},"2026-11-30",{"name":5,"class":6},6]