[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100516372":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Oslo","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients",null,"Adult recipients of allo-HCST.",{"label":13,"type":10,"description":14,"interventionNames":10},"Controls","Healthy adult subjects",[16],{"name":17,"affiliation":5,"role":18},"Per Ole Iversen, phd","STUDY_DIRECTOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+47 22 85 13 91","p.o.iversen@medisin.uio.no",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Mahnoor Nazar, master","+47 97603124","Mahnoor.Nazar@odont.uio.no",[29],{"facility":5,"status":30,"city":31,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Oslo","0254","Norway","NO",{"type":36,"coordinates":37},"Point",[38,39],10.74609,59.91273,{"lat":39,"lon":38},[42,44],{"name":17,"role":21,"phone":43,"phoneExt":10,"email":23},"+4722851391",{"name":45,"role":21,"phone":46,"phoneExt":10,"email":47},"Åsmund Rogn","+4795800328","aasmunro@odont.uio.no",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Per Ole Iversen, MD","Professor","100516372","oral-chemosensory-and-trigeminal-functions-in-allo-hsct-100516372",false,"NCT06003660","Oral, Chemosensory and Trigeminal Functions in Allo-HSCT","Oral, Chemosensory and Trigeminal Functions in Allogeneic Hematopoietic Stem Cell Transplantation - a Prospective Cohort-study","Inclusion Criteria:\n\n• patients receiving myeloablative conditioning for a first-time allo-HSCT and diagnosed with either a leukemia or a myelodysplastic syndrome\n\nExclusion Criteria:\n\n* disorders affecting the oral cavity including poor tooth-status\n* those using drugs affecting the gustatory\u002Folfactory functions\n* those with brain disorders\n* those who have a chronic disorder affecting the immune system, have cancer or who are pregnant.",true,"ALL","30 Years","70 Years",{"count":64,"type":65},70,"ESTIMATED","OBSERVATIONAL","The goal of this prospective, cohort study is to learn about smell, taste and trigeminal dysfunction in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). The research team hypothesizes that treatment with allo-HSCT will induce:\n\n* Distortion of taste and smell and trigeminal functions like cooling, tingling, and burning sensations.\n* Reduced saliva production leading to oral dryness and dental caries.\n* Changes in the connectivity of the taste-, smell- and pain-cortical brain regions.",[69],"Hematopoietic Stem Cell Transplantation","2026-04-27",{"date":72,"type":73},"2026-05-01","ACTUAL",{"date":75,"type":73},"2023-08-10",{"date":77,"type":65},"2028-03-01",{"name":5,"class":6},1]