[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496126":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":93,"collaborators":96,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":21,"eligibilityCriteria":105,"healthyVolunteers":102,"sex":106,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":21,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":42,"whyStopped":21,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"Tampere University Hospital","OTHER",[8,14,17,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Egg allergy with asthma with intervention","EXPERIMENTAL","Immunotherapy Egg product including egg white and yolk allergens",[13],"Dietary Supplement: Egg product including egg white and yolk allergens",{"label":15,"type":10,"description":11,"interventionNames":16},"Egg allergy without asthma with intervention",[13],{"label":18,"type":19,"description":20,"interventionNames":21},"Egg allergy with asthma without intervention","NO_INTERVENTION","No intervention, control",null,{"label":23,"type":19,"description":20,"interventionNames":21},"Egg allergy without asthma without intervention",[25],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":21},"DIETARY_SUPPLEMENT","Egg product including egg white and yolk allergens","Egg product either meatball or bread roll or bun including egg white and yolk allergens delivered orally in increasing dosages daily.",[9,15],[31],{"name":32,"affiliation":5,"role":33},"Rüdiger Schultz, MD., PhD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":21,"email":38},"CONTACT","+358","rudiger.schultz58@gmail.com",[40,67],{"facility":41,"status":42,"city":43,"state":21,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Oulu University Hospital","RECRUITING","Oulu","90230","Finland","FI",{"type":48,"coordinates":49},"Point",[50,51],25.46816,65.01236,{"lat":51,"lon":50},[54,58,61,63,65],{"name":55,"role":36,"phone":56,"phoneExt":21,"email":57},"Petri Kulmala, Clinical Professor","+35883155534","petri.kulmala@oulu.fi",{"name":59,"role":36,"phone":60,"phoneExt":21,"email":21},"Lotta Kinnunen, MD., PhD","+35883155825",{"name":59,"role":62,"phone":21,"phoneExt":21,"email":21},"SUB_INVESTIGATOR",{"name":64,"role":62,"phone":21,"phoneExt":21,"email":21},"Teija Dunder, MD., PhD",{"name":66,"role":33,"phone":21,"phoneExt":21,"email":21},"Petri Kulmala, MD., PhD",{"facility":5,"status":42,"city":68,"state":21,"zip":69,"country":45,"countryCode":46,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Tampere","33520",{"type":48,"coordinates":71},[72,73],23.78712,61.49911,{"lat":73,"lon":72},[76,78,80,82,84,86,88,90,92],{"name":32,"role":36,"phone":21,"phoneExt":21,"email":77},"rudiger.schultz@pirha.fi",{"name":79,"role":62,"phone":21,"phoneExt":21,"email":21},"Lauri Lehtimäki, MD., PhD",{"name":81,"role":62,"phone":21,"phoneExt":21,"email":21},"Heli Aldénv, M.Sc.",{"name":83,"role":62,"phone":21,"phoneExt":21,"email":21},"Iida Ojaniemi, MD",{"name":85,"role":62,"phone":21,"phoneExt":21,"email":21},"Jussi Karjalainen, MD., PhD",{"name":87,"role":62,"phone":21,"phoneExt":21,"email":21},"Heini Huhtala, M.Sc.",{"name":89,"role":62,"phone":21,"phoneExt":21,"email":21},"Susanna Salmivesi, MD., PhD",{"name":91,"role":62,"phone":21,"phoneExt":21,"email":21},"Juho Kivistö, MD., PhD",{"name":32,"role":33,"phone":21,"phoneExt":21,"email":21},{"type":33,"investigatorFullName":94,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Rudiger Schultz","Specialist in Pediatric Allergology",[97,99],{"name":98,"class":6},"University of Oulu",{"name":41,"class":6},"100496126","oral-immunotherapy-for-egg-allergy-in-children-aged-6-to-16-100496126",false,"NCT05740163","Oral Immunotherapy for Egg Allergy in Children Aged 6 to 16","Inclusion Criteria:\n\n* Age 6 to 16 years\n* Elevated spesific serum IgE to egg (\\> 5 kU\u002Fl) and\u002For positive skin prick to egg allergen\n* Positive oral food challenge for egg or anaphylaxis reaction to egg within the 6 months\n* Diet free from egg in any form\n\nExclusion Criteria:\n\n* Age less than 6 years or more than 16 years\n* Poor asthma control or uncontrolled asthma\n* Severe\u002Fsignificant cardiovascular disease\n* Autoimmune disease\n* Malignancy\n* Medication: beta bloker, angiotensin-converting-enzyme inhibitors (ACE inhibitors), Monoamine oxidase inhibitors (MAOIs)\n* Poor compliance\n* Fear of immunotherapy\n* Desensitization to alfa-gal-protein (mammalian meat allergy)","ALL","6 Years","16 Years",{"count":110,"type":111},60,"ESTIMATED","INTERVENTIONAL",[114],"NA","The aim of the study is to determine the efficacy of a 12-month egg oral immunotherapy (OIT) protocol with a cooked whole egg product including yolk and egg white.\n\nStudy hypothesis: With this method the risk for severe allergic reaction to egg protein is reduced and the diet can partly or completely be normalized.",[117],"Egg Allergy",[119,120,121],"Oral immunotherapy","Egg allergy","Children","2024-04-09",{"date":124,"type":125},"2024-04-10","ACTUAL",{"date":127,"type":125},"2019-12-30",{"date":129,"type":111},"2026-12-31",{"name":5,"class":6},2]