[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613640":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":57,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Veterinary and Animal Sciences, Lahore - Pakistan","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"1","PLACEBO_COMPARATOR","Intervention Type: Drug Intervention Name: Placebo Capsule\n\nDescription:\n\n\"An inactive oral placebo capsule that contains no Vitamin D3. It is matched in appearance and administration schedule to the active supplement and is used to maintain blinding.\"",[13],"Drug: Vitamin D3",{"label":15,"type":16,"description":17,"interventionNames":18},"2","EXPERIMENTAL","Intervention Type: Drug Intervention Name: Vitamin D3\n\nDescription:\n\n\"This intervention consists of oral Vitamin D3 (cholecalciferol) capsules administered every two weeks to improve vitamin D status. The dose is designed to raise serum 25(OH)D levels. Adherence will be monitored using supplement logs and follow-up visits.\"",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Vitamin D3","This intervention consists of oral Vitamin D3 (cholecalciferol) capsules administered every two weeks for the duration of the study. The dose is designed to raise and maintain adequate serum 25-hydroxyvitamin D levels. Participants will receive the active supplement under supervised distribution, and adherence will be monitored through supplement logs and follow-up visits",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Dr. Qaisar Raza, PhD","UNIVERSITY OF VETERINARY & ANIMAL SCIENCES, LAHORE","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Muhammad Barkaat Azam, PhD Scholar","CONTACT","923336654554","barkaatazam@gmail.com",{"name":28,"role":34,"phone":38,"phoneExt":25,"email":39},"923002479044","qaisar.raza@uvas.edu.pk",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"University of Veterinary & Animal Sciences, Lahore","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":50,"coordinates":51},"Point",[52,53],74.35071,31.558,{"lat":53,"lon":52},[56],{"name":28,"role":34,"phone":38,"phoneExt":25,"email":39},{"type":30,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Qaisar Raza","Assistant Professor","100613640","oral-vitamin-d3-effect-on-inflammatory-biomarkers-in-ulcerative-colitis-patients-100613640",false,"NCT07269223","Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients","Effect Of Oral Vitamin D3 Supplementation On Inflammatory Biomarkers In Patients With Ulcerative Colitis","OVDIEIBUCP","Inclusion Criteria:\n\n* • All patients diagnosed previously by standard clinical i.e Truelove and Witts and endoscopic\u002F colonoscopic criteria\n\n  * Patients with moderate ulcerative colitis will be included\n  * Both male and female patients will be included in the study\n  * No change in the type and dosage of their medicine over the past month\n  * Patient with severe vitamin D deficiency (\\\u003C 10 ng\u002FmL) after screening\n  * Patients who will provide written informed consent\n  * Age: 20-40 year\n\nExclusion Criteria:• Patients using Vitamin D supplement in the 3 months before the study\n\n* Patients suffering from Crohn's disease or any known autoimmune disease\n* Patients with mild and severe ulcerative colitis\n* Changes in the type and dosage of the drug during the study\n* Pregnant and lactating women\n* Patients with known kidney disease\n* Patients with known liver disease","ALL","20 Years","40 Years",{"count":72,"type":73},60,"ESTIMATED","INTERVENTIONAL",[76],"NA","This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis. Sixty patients will be randomized to receive either standard treatment alone\u002FPlacebo or standard treatment plus vitamin D3 (50,000 IU fortnightly) for 12 weeks. Primary outcomes include changes in blood (CRP, ESR, IL-6) and fecal (calprotectin) inflammatory biomarkers, and disease activity assessed by the partial Mayo score. Secondary outcomes include vitamin D status, dietary intake, and quality of life. The study will provide insights into the immune-modulating and anti-inflammatory role of vitamin D3 as an adjunct therapy in ulcerative colitis.",[79],"Ulcerative Colitis (UC)",[81,82,83],"Ulcerative Colitis","Vitamin D","Immune modulation","2025-12-09",{"date":86,"type":87},"2025-12-17","ACTUAL",{"date":89,"type":87},"2025-09-02",{"date":91,"type":73},"2025-12-30",{"name":5,"class":6},1]