[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545356":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":31,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"West China Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pancreatitis with sepsis patients' organ dysfunction progression after open necrosectomy",null,"Acute necrotizing pancreatitis patients with sepsis undergoing open necrosectomy will be measured SOFA scores at a special time point to characterize organ dysfunction experience profiles.",[13],"Other: Necrotizing Pancreatitis patients' organ dysfunction progression",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Necrotizing Pancreatitis patients' organ dysfunction progression","Study the dynamic nature of organ dysfunction",[9],[20],{"name":21,"affiliation":5,"role":22},"Fengming Luo, PhD","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Chunling Jiang, PhD","CONTACT","18980601096","jiangchunling@scu.edu.cn",{"name":30,"role":26,"phone":27,"phoneExt":10,"email":28},"Qian Li, PhD",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":36,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"West China Hospital, Sichuan University","RECRUITING","Chengdu","China","610041","CN",{"type":40,"coordinates":41},"Point",[42,43],104.06667,30.66667,{"lat":43,"lon":42},[46],{"name":21,"role":26,"phone":47,"phoneExt":10,"email":28},"02885423593",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Chunling Jiang","Professor","100545356","organ-dysfunction-change-in-acute-necrotizing-pancreatitis-patients-with-sepsis-after-open-necrosectomy-100545356",false,"NCT06380842","Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy","Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis Undergoing Open Necrosectomy","Inclusion Criteria:\n\n1. Patients 18 years or older\n2. Diagnosis of Acute pancreatitis according to the revised Atlanta classification, requires two of the following three criteria: (A) typical abdominal pain, (B) an increase in serum amylase or lipase levels higher than three times the upper limit of normality, and (C) signs of AP in imaging\n3. Patients with confirmed or suspected infected pancreatic or peripancreatic necrosis were scheduled for open necrosectomy\n4. Meet Sepsis-3 criteria\n\nExclusion Criteria:\n\n1. Patients refuse to participate\n2. Patients undergo repeat surgery on the same site","ALL","18 Years",{"count":62,"type":63},200,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to characterize organ dysfunction change in acute necrotizing pancreatitis patients with sepsis after open necrosectomy.",[67],"Necrotizing Pancreatitis",[69,70,71],"Acute Necrotizing Pancreatitis","sepsis","organ dysfunction","2025-09-18",{"date":74,"type":75},"2025-09-23","ACTUAL",{"date":77,"type":75},"2024-06-15",{"date":79,"type":63},"2026-12-30",{"name":50,"class":6},1]