[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608414":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":41,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":10,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":10,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"West China Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pancreatitis with sepsis patients' organdysfunction progression after opennecrosectomy",null,"SOFA scores at predefined time points were retrospectively extracted from the institutional database in acute necrotizing pancreatitis patients with sepsis who underwent open necrosectomy to characterize organ dysfunction trajectories",[13],"Other: Necrotizing Pancreatitis patients' organdysfunction progression",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Necrotizing Pancreatitis patients' organdysfunction progression","Study the dynamic nature of organ dysfunction",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Chunling Jiang, PhD","CONTACT","02885423593","jiangchunling@scu.edu.cn",[26],{"facility":27,"status":10,"city":28,"state":29,"zip":30,"country":29,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"West China Hospital, Sichuan University","Chengdu","China","610041","CN",{"type":33,"coordinates":34},"Point",[35,36],104.06667,30.66667,{"lat":36,"lon":35},[39],{"name":40,"role":22,"phone":23,"phoneExt":10,"email":24},"Fengming Luo, PhD",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Chunling Jiang","Professor","100608414","organ-dysfunction-changes-in-acute-necrotizing-pancreatitis-patients-with-sepsis-following-open-necrosectomy-100608414",false,"NCT07201246","Organ Dysfunction Changes in Acute Necrotizing Pancreatitis Patients With Sepsis Following Open Necrosectomy","Retrospective Analysis of Organ Dysfunction Changes in Acute Necrotizing Pancreatitis Patients With Sepsis Following Open Necrosectomy：A Retrospective Cohort Study","Inclusion Criteria:\n\n1. Patients 18 years or older\n2. Diagnosis of Acute pancreatitis according to the revised Atlanta classification, requires two of thefollowing three criteria: (A) typical abdominal pain, (B) an increase in serum amylase or lipaselevels higher than three times the upper limit of normality, and (C) signs of AP in imaging3)Patients with confirmed or suspected infected pancreatic or peripancreatic necrosis werescheduled for open necrosectomy\n3. Meet Sepsis-3 criteria\n\nExclusion Criteria:\n\nPatients undergo repeat surgery on the same site","ALL","18 Years",{"count":55,"type":56},700,"ESTIMATED","OBSERVATIONAL","The purpose of this retrospective study was to characterize the changes in organ dysfunction among patients with acute necrotizing pancreatitis complicated by sepsis who underwent open necrosectomy.",[60],"Necrotizing Pancreatitis","NOT_YET_RECRUITING","2025-09-23",{"date":64,"type":65},"2025-10-01","ACTUAL",{"date":67,"type":56},"2025-10-05",{"date":69,"type":56},"2026-12-30",{"name":5,"class":6},1]