[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634371":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":15,"collaborators":10,"id":19,"slug":20,"hasResults":21,"nctId":22,"briefTitle":23,"officialTitle":24,"acronym":10,"eligibilityCriteria":25,"healthyVolunteers":26,"sex":27,"minAge":28,"maxAge":29,"enrollmentInfo":30,"targetDuration":10,"studyType":33,"phases":10,"briefSummary":34,"conditions":35,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":44,"leadSponsor":46,"locationsCount":10},{"fullName":5,"class":6},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"low-flow anesthesia",null,"0,5 lt\u002Fmin",{"label":13,"type":10,"description":14,"interventionNames":10},"normal flow anesthesia","2 lt\u002Fmin",{"type":16,"investigatorFullName":17,"investigatorTitle":18,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hilal AKCA","M.D.","100634371","ori-monitoring-in-low-and-normal-flow-anesthesia-applications-100634371",false,"NCT07538817","ORI MONITORING IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS","EVALUATION OF OXYGEN RESERVE INDEX IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS IN LAPAROSCOPIC NEPHRECTOMY CASES IN LATERAL DECUBIT POSITION","Inclusion Criteria:\n\n* Ages 18-75\n* ASA I,II\n* elective surgery laparoscopic nephrectomy\n\nExclusion Criteria:\n\n* ASA III,IV,V\n* BMI \\> 35\n* Those with serious respiratory disease\n* Medications that cause peripheral circulation disorders\n* Patients who started with laparoscopic surgery and then underwent open surgery",true,"ALL","18 Years","75 Years",{"count":31,"type":32},48,"ESTIMATED","OBSERVATIONAL","Oxygen administration is essential in the perioperative period to prevent hypoxia; however, excessive oxygen may cause hyperoxia and related complications. While pulse oximetry is effective in detecting hypoxemia, it is insufficient for identifying hyperoxia when SpO₂ exceeds 97%, often necessitating invasive arterial blood gas analysis. The Oxygen Reserve Index (ORI) is a noninvasive, real-time monitoring parameter reflecting moderate hyperoxic ranges (PaO₂ 100-200 mmHg) and provides early warning of oxygenation changes before SpO₂ alterations occur. Combined use of ORI and pulse oximetry may enable optimal oxygen titration and prevention of both hypoxemia and hyperoxemia.\n\nLaparoscopic nephrectomy is widely performed due to its clinical advantages. In our practice, low and normal fresh gas flow anesthesia are commonly used. Low-flow anesthesia offers benefits such as preservation of heat and humidity, reduced cost, and improved airway physiology. This study aims to determine optimal oxygenation levels during laparoscopic nephrectomy under low and normal fresh gas flow conditions using ORI monitoring.",[36,37],"HYPEROXY","OXYGEN RESERVE INDEX","NOT_YET_RECRUITING","2026-04-13",{"date":41,"type":42},"2026-04-20","ACTUAL",{"date":41,"type":32},{"date":45,"type":32},"2026-08-20",{"name":5,"class":6}]