[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635419":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":35,"responsibleParty":50,"collaborators":24,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":24,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":38,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Yuzuncu Yil University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Maxillary Constriction Group","EXPERIMENTAL","This arm includes skeletal Class I patients (aged 12-25) diagnosed with maxillary transversal constriction. Participants in this group will undergo perioral muscle pressure measurements (tongue, lip, and cheek pressures) using the Iowa Oral Performance Instrument (IOPI) in kilopascals (kPa) before the initiation of any orthodontic treatment.",[13],"Diagnostic Test: Orolingual Manometry using IOPI Pro Deluxe Kit",{"label":15,"type":10,"description":16,"interventionNames":17},"Control Group (Normal Maxillary Width)","This arm includes skeletal Class I patients (aged 12-25) with normal maxillary transversal width. This group serves as the baseline for healthy perioral muscle function. Participants will undergo the same standardized pressure measurement protocol using the IOPI device to provide comparative data for the experimental group.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","Orolingual Manometry using IOPI Pro Deluxe Kit","A standardized measurement of perioral muscle pressures (tongue, lip, and cheek) will be conducted using the Iowa Oral Performance Instrument (IOPI). The procedure involves placing a disposable, air-filled bulb at specific intraoral locations (e.g., retro-incisal for tongue pressure, buccal vestibule for cheek pressure). Participants are instructed to exert their maximum isometric force against the bulb for a specific duration. Each measurement is performed three times with 30-second rest intervals, and the peak pressure is recorded in kilopascals (kPa). This procedure is purely diagnostic and non-invasive, performed once for each participant before the initiation of any orthodontic intervention.",[15,9],null,[26,31],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Saadet Çınarsoy Ciğerim, assoc prof","CONTACT","+905054870692","saadetcinarsoy@live.com",{"name":32,"role":28,"phone":33,"phoneExt":24,"email":34},"Gönül Dinç, assist prof","+905063094630","gonuldinc@hotmail.com",[36],{"facility":37,"status":38,"city":39,"state":39,"zip":24,"country":40,"countryCode":24,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Van Yüzüncü Yıl University, Faculty of Dentistry, Department of Orthodontics","RECRUITING","Van","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],43.38323,38.49457,{"lat":45,"lon":44},[48,49],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},{"name":32,"role":28,"phone":33,"phoneExt":24,"email":34},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Gönül Dinç","assist prof","100635419","orofacial-muscle-pressure-and-maxillary-transverse-development-100635419",false,"NCT07552441","Orofacial Muscle Pressure and Maxillary Transverse Development","Investigation of the Effect of Lip, Cheek, and Tongue Muscle Pressure on Maxillary Transverse Development","OMPTD","Inclusion Criteria:Participants aged between 12 and 25 years.Diagnosed as Skeletal Class I (ANB angle: $0\\^\\\\circ$ to $4\\^\\\\circ$).Experimental Group: Clinical and radiographic diagnosis of maxillary transversal constriction.Control Group: Normal maxillary transversal width with no crossbite or constriction.Permanent dentition (excluding third molars).Good oral hygiene and no active periodontal disease.Ability to understand and follow instructions for the IOPI measurement protocol.\n\n\\-\n\nExclusion Criteria:Previous orthodontic or orthognathic surgical treatment.\n\nHistory of craniofacial anomalies or syndromes (e.g., cleft lip and palate).\n\nNeuromuscular disorders or systemic diseases affecting muscle function.\n\nHistory of trauma to the jaw or facial region.\n\nCongenitally missing teeth (hypodontia) or extensive prosthetic restorations.\n\nMacroglossia or severe tongue-tie (ankyloglossia).\n\nUse of medications that may influence muscle tone (e.g., muscle relaxants).\n\nPresence of large tonsils or adenoids that significantly obstruct the airway.\n\n\\-",true,"ALL","12 Years","25 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","Study Title: Investigation of the Effects of Tongue, Lip, and Cheek Pressures on the Development of Upper Jaw Narrowness\n\nIntroduction and Hypothesis The structure of our face and the alignment of our teeth are influenced not only by our genetics but also by the surrounding soft tissues, such as the lips, cheeks, and tongue. These muscles exert constant pressure on our teeth and jawbones. According to the \"Equilibrium Theory,\" teeth stay in their proper positions when the inward pressure from the lips and cheeks is balanced by the outward pressure from the tongue.\n\nThe hypothesis of this study is that individuals with a narrow upper jaw (maxillary constriction) may have different muscle pressure patterns compared to those with normal jaw widths. We believe that identifying these pressure differences will help dentists and orthodontists better understand why jaw narrowness occurs and how to achieve more stable results after treatment.\n\nWhat is Being Measured? To measure these delicate pressures, we use a specialized, high-tech device called the Iowa Oral Performance Instrument (IOPI). This device uses a small, air-filled balloon (bulb) that the patient presses with their tongue or lips. It allows us to measure muscle strength and endurance in \"kilopascals\" (a unit of pressure) without any pain or discomfort.\n\nStudy Procedure\n\nThis study will involve patients aged 12 to 25 who are seeking orthodontic treatment at Van Yüzüncü Yıl University. We will divide the participants into two groups:\n\nPatients with a narrow upper jaw.\n\nPatients with a normal upper jaw width (the control group).\n\nBefore any orthodontic braces are applied, we will measure:\n\nTongue Pressure: How hard the tongue can push against the roof of the mouth.\n\nLip Pressure: The strength of the upper and lower lips.\n\nCheek (Buccal) Pressure: The pressure exerted by the cheeks during rest and function.\n\nImportance of the Study While many studies have looked at how these muscles affect the forward or backward position of teeth, there is very little research on how they affect the width of the jaw. By comparing these two groups, we hope to discover whether \"weak\" or \"overactive\" muscles contribute to a narrow palate. This information could lead to new treatment methods that focus not just on moving teeth, but also on training the oral muscles to ensure that the beautiful smiles created by orthodontists last a lifetime.",[74],"Maxillary Transversal Deficiency (Maxillary Constriction) and Perioral Muscle Pressures (Tongue, Lip, and Cheek)",[76,77,78,79],"Maxillary transversal deficiency","Perioral muscle pressure","Tongue and lip strength","Iowa Oral Performance Instrument (IOPI)","2026-04-20",{"date":82,"type":83},"2026-04-27","ACTUAL",{"date":85,"type":68},"2026-05-01",{"date":87,"type":68},"2026-12-01",{"name":5,"class":6},1]