[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641225":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":45,"centralContacts":50,"locations":55,"responsibleParty":70,"collaborators":32,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":74,"sex":80,"minAge":81,"maxAge":32,"enrollmentInfo":82,"targetDuration":32,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":98,"whyStopped":32,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Shanghai Pudong New Area Gongli Hospital","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Oropharyngeal Flushing Suction Tube Plus Laryngoscope","EXPERIMENTAL","Participants receive standard stroke care and routine oral care plus direct laryngoscope-guided suction using the oropharyngeal flushing suction tube. Sterile saline irrigation of approximately 5 mL may be delivered through the irrigation lumen with simultaneous suction when secretions are tenacious.",[13,14],"Device: Oropharyngeal Flushing Suction Tube","Procedure: Laryngoscope-Guided Oropharyngeal Suction",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard Suction Tube Plus Laryngoscope","ACTIVE_COMPARATOR","Participants receive standard stroke care and routine oral care plus direct laryngoscope-guided suction using a standard single-lumen suction catheter. No oropharyngeal flushing suction tube is used.",[14,20],"Device: Standard Suction Catheter",{"label":22,"type":17,"description":23,"interventionNames":24},"Conventional Oral or Nasal Suction","Participants receive standard stroke care and routine oral care plus conventional blind oral and\u002For nasal suction using a standard suction catheter. No laryngoscope and no flushing suction tube are used.",[25],"Procedure: Conventional Oral or Nasal Suction",[27,33,38,42],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Oropharyngeal Flushing Suction Tube","A patented single-use dual-lumen suction tube designed for simultaneous irrigation and suction of oropharyngeal and deep pharyngeal secretions under direct laryngoscopic visualization. The device includes separate irrigation and suction lumens and allows sterile saline irrigation with simultaneous suction when secretions are tenacious.",[9],null,{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":32},"PROCEDURE","Laryngoscope-Guided Oropharyngeal Suction","Direct laryngoscopy is used to visualize the oropharyngeal and glottic area and guide targeted suctioning of oropharyngeal and deep pharyngeal secretions.",[9,16],{"type":28,"name":39,"description":40,"armGroupLabels":41,"otherNames":32},"Standard Suction Catheter","A conventional single-lumen suction catheter used for oropharyngeal or airway secretion suctioning according to routine clinical practice.",[16],{"type":34,"name":22,"description":43,"armGroupLabels":44,"otherNames":32},"Blind oral and\u002For nasal suctioning performed with a standard suction catheter according to routine clinical practice, without direct laryngoscopic visualization and without use of the oropharyngeal flushing suction tube.",[22],[46],{"name":47,"affiliation":48,"role":49},"Qiancheng Luo, MD","Pudong Gongli Hospital, Shanghai University of Medicine & Health Sciences","PRINCIPAL_INVESTIGATOR",[51],{"name":47,"role":52,"phone":53,"phoneExt":32,"email":54},"CONTACT","+86 13564781737","luoqiancheng19@163.com",[56],{"facility":48,"status":32,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Shanghai","Shanghai Municipality","200135","China","CN",{"type":63,"coordinates":64},"Point",[65,66],121.45806,31.22222,{"lat":66,"lon":65},[69],{"name":47,"role":52,"phone":53,"phoneExt":32,"email":54},{"type":49,"investigatorFullName":47,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Principal Investigator","100641225","oropharyngeal-flushing-suction-tube-with-laryngoscope-for-stroke-associated-pneumonia-100641225",false,"NCT07647666","Oropharyngeal Flushing Suction Tube With Laryngoscope for Stroke-Associated Pneumonia","Translational Application of an Oropharyngeal Flushing Suction Tube Combined With Laryngoscope for Improving Prognosis in Stroke-Associated Pneumonia: A Prospective Randomized Controlled Trial","OFST-SAP","Inclusion Criteria:\n\n1. Confirmed acute ischemic stroke by cranial CT or MRI.\n2. Age 18 years or older.\n3. Glasgow Coma Scale score of 6 to 12.\n4. No artificial airway and no requirement for invasive mechanical ventilation at enrollment.\n5. Written informed consent provided by the participant or legally authorized representative.\n\nExclusion Criteria:\n\n1. Existing artificial airway or invasive mechanical ventilation at ICU admission or screening.\n2. Pre-existing pulmonary infection at enrollment, or definite extra-pulmonary organ or tissue infection during the study period.\n3. Hemorrhagic blood disorder, clinically significant coagulopathy, or bleeding risk precluding laryngoscopy.\n4. Oral or maxillofacial deformity impeding laryngoscope insertion.\n5. Cervical spine fracture, atlantoaxial instability, or other condition restricting neck extension or movement.\n6. Confirmed or suspected pregnancy.\n7. Irreversible critical illness with anticipated survival less than 28 days.\n8. Uncontrolled hypertension or recurrent malignant arrhythmias.\n9. Other conditions judged by investigators to make participation unsuitable.","ALL","18 Years",{"count":83,"type":84},120,"ESTIMATED","INTERVENTIONAL",[87],"NA","Stroke-associated pneumonia is a common and clinically important complication after acute ischemic stroke, especially in non-intubated patients with impaired consciousness and reduced cough or swallowing reflexes. Conventional oral or nasal suction may be insufficient for removing deep oropharyngeal secretions. This prospective randomized controlled trial will evaluate whether a patented oropharyngeal flushing suction tube combined with direct laryngoscopy reduces the 28-day incidence of stroke-associated pneumonia compared with laryngoscope-guided standard suction and conventional oral\u002Fnasal suction.",[90,91],"Acute Ischemic Stroke","Stroke-Associated Pneumonia (SAP)",[93,94,95,96,97],"Oropharyngeal Suction","Laryngoscope","Airway Management","Suction Tube","Aspiration Pneumonia","NOT_YET_RECRUITING","2026-06-17",{"date":101,"type":102},"2026-06-18","ACTUAL",{"date":104,"type":84},"2026-08-01",{"date":106,"type":84},"2029-07-31",{"name":5,"class":6},1]