[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583273":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":49,"centralContacts":53,"locations":62,"responsibleParty":77,"collaborators":29,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":29,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":29,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":104,"whyStopped":29,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: Pre-intubation oropharyngeal topical %10 lidocaine","EXPERIMENTAL","Participants will receive 10% lidocaine spray topically to the oropharynx before intubation.",[13,14,15,16,17],"Diagnostic Test: Optic nerve sheath diameter measurement 0","Diagnostic Test: optic nerve sheath diameter measurement 1","Diagnostic Test: optic nerve sheath diameter measurement 2","Diagnostic Test: optic nerve sheath diameter measurement 3","Procedure: Pre-intubation oropharyngeal topical %10 lidocaine",{"label":19,"type":10,"description":20,"interventionNames":21},"Group B: Pre-intubation intravenous %2 lidocaine","Participants will receive 2% lidocaine intravenously before intubation.",[13,14,15,16,22],"Procedure: Pre-intubation intravenous %2 lidocaine",[24,30,34,38,42,46],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DIAGNOSTIC_TEST","Optic nerve sheath diameter measurement 0","optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation",[9,19],null,{"type":25,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"optic nerve sheath diameter measurement 1","optic nerve sheath diameter measurement 1 via ultrasonography after intubation 1st minute",[9,19],{"type":25,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"optic nerve sheath diameter measurement 2","optic nerve sheath diameter measurement via ultrasonography after intubation 5th minute",[9,19],{"type":25,"name":39,"description":40,"armGroupLabels":41,"otherNames":29},"optic nerve sheath diameter measurement 3","optic nerve sheath diameter measurement via ultrasonography after intubation 10th minute",[9,19],{"type":43,"name":44,"description":44,"armGroupLabels":45,"otherNames":29},"PROCEDURE","Pre-intubation oropharyngeal topical %10 lidocaine",[9],{"type":43,"name":47,"description":47,"armGroupLabels":48,"otherNames":29},"Pre-intubation intravenous %2 lidocaine",[19],[50],{"name":51,"affiliation":5,"role":52},"İsmail Aytaç, Ass. Prof","PRINCIPAL_INVESTIGATOR",[54,59],{"name":55,"role":56,"phone":57,"phoneExt":29,"email":58},"İsmail Aytaç, Ass. prof","CONTACT","+90 505 634 03 69","aytacismail1972@gmail.com",{"name":60,"role":56,"phone":29,"phoneExt":29,"email":61},"Dilan Yazar Doğan, resident","yazardilan@gmail.com",[63],{"facility":64,"status":29,"city":65,"state":66,"zip":67,"country":68,"countryCode":29,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"Ankara Bilkent City Hospital","Ankara","Turkey","06800","Turkey (Türkiye)",{"type":70,"coordinates":71},"Point",[72,73],32.85427,39.91987,{"lat":73,"lon":72},[76],{"name":55,"role":56,"phone":57,"phoneExt":29,"email":58},{"type":52,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"ismail aytaç","Ass.Prof.Dr. İsmail Aytaç","100583273","oropharyngeal-vs-intravenous-lidocaine-effects-on-optic-nerve-sheath-diameter-after-intubation-100583273",false,"NCT06874179","Oropharyngeal Vs Intravenous Lidocaine Effects on Optic Nerve Sheath Diameter After Intubation","Effects of Oropharyngeal-topical and Intravenous Lidocaine on the Optic Nerve Sheath Diameter Changes After Endotracheal Intubation: a Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* ASA class I or II\n* Age 18-65 years\n* BMI 18-30\n* No history or expected difficult intubation\n* No glaucoma or ocular pathology\n* No intracranial pressure increase\n\nExclusion Criteria:\n\n* ASA class III and above\n* Obesity (BMI \\> 30)\n* Difficult intubation history or risk\n* Glaucoma or other ophthalmic pathology\n* History of intracranial pressure increase or prior ophthalmic\u002Fintracranial surgery\n* Preoperative sedation\n* Active malignancy or ongoing radiotherapy\u002Fchemotherapy","ALL","18 Years","65 Years",{"count":91,"type":92},190,"ESTIMATED","INTERVENTIONAL",[95],"NA","This study aims to evaluate the effects of pre-intubation oropharyngeal topical lidocaine on optic nerve sheath diameter (ONSD) post-endotracheal intubation. The study will measure the ONSD using ultrasonography before intubation, and at 1, 5, and 10 minutes post-intubation. The results will be compared between patients receiving %10 lidocaine topically and %2 intravenous lidocaine.",[98,99],"Endotracheal Intubation During Surgery","Optic Nerve Sheath Diameter",[101,102,103],"endotracheal intubation","optic nerve sheath diameter","lidocaine","NOT_YET_RECRUITING","2025-03-08",{"date":107,"type":108},"2025-03-13","ACTUAL",{"date":110,"type":92},"2025-03-20",{"date":112,"type":92},"2025-11-30",{"name":5,"class":6},1]