[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633942":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":20,"locations":21,"responsibleParty":41,"collaborators":20,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":20,"enrollmentInfo":55,"targetDuration":20,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":24,"whyStopped":20,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Liege","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Post-Treatment CBCT, Intraoral Scan, and Modjaw Assessment","EXPERIMENTAL","All participants treated with the OSNPO protocol undergo additional diagnostic assessments performed specifically for research purposes after completion of their routine clinical treatment.\n\nThese research-only procedures include:\n\n* a low-dose, large-field CBCT scan to evaluate tooth movements, vertical facial dimensions, and temporomandibular joint position;\n* a digital intraoral scan to document occlusal contacts and dental morphology;\n* a Modjaw 3D jaw-tracking recording to assess mandibular function and occlusal dynamics.",[13],"Radiation: Low-dose Cone-Beam Computed Tomography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"RADIATION","Low-dose Cone-Beam Computed Tomography","Acquisition of a low-dose, large-field CBCT scan performed specifically for research purposes after completion of the OSNPO treatment, used to assess tooth movements, vertical facial dimensions, and temporomandibular joint position.",[9],null,[22],{"facility":23,"status":24,"city":25,"state":20,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"University Hospital of Liège","RECRUITING","Liège","4000","Belgium","BE",{"type":30,"coordinates":31},"Point",[32,33],5.56749,50.63373,{"lat":33,"lon":32},[36],{"name":37,"role":38,"phone":39,"phoneExt":20,"email":40},"Amélie Mainjot","CONTACT","+3243233106","a.mainjot@chuliege.be",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Mainjot Amélie","Professor","100633942","orthodontic-and-articular-effects-of-the-one-step-no-prep-protocol-100633942",false,"NCT07533240","Orthodontic and Articular Effects of the One-Step No-Prep Protocol","Investigation of the Orthodontic and Articular Effects of the One-Step No-Prep Protocol","OSNPO","Inclusion Criteria:\n\n* Localized tooth wear that will be treated, or has already been treated, using the OSNPO protocol.\n* Age 18 years or older.\n* Sufficient cognitive ability to understand the study procedures and complete the required assessments.\n* Ability to read and complete the study questionnaires in French.\n* Written informed consent provided.\n\nExclusion Criteria:\n\n* No exclusion criteria.","ALL","18 Years",{"count":56,"type":57},30,"ESTIMATED","INTERVENTIONAL",[60],"NA","This study investigates how the One-Step No-Prep protocol with orthodontic assistance affects dental and jaw function in adults treated for localized tooth wear. It focuses on the predictability and extent of orthodontic tooth movements, the impact on temporomandibular joint position and function, and the quality and long-term stability of the restored bite.\n\nParticipants will receive minimally invasive bonded restorations combined with simple orthodontic mechanics. The study will evaluate changes in tooth position, bite contacts, facial vertical height, and temporomandibular joint function using digital scans, low-dose 3D imaging, jaw-tracking, and clinical examinations. Patient comfort, function, and satisfaction will also be assessed through questionnaires.\n\nThe goal is to better understand how this conservative treatment performs over time.",[63,64],"Tooth Wear","Orthodontic Extrusion",[66,67,68,69],"Localized tooth wear","Orthodontic tooth movement","Minimally invasive dentistry","PICN restorations","2026-04-14",{"date":72,"type":73},"2026-04-16","ACTUAL",{"date":75,"type":57},"2026-04",{"date":77,"type":57},"2041-02-24",{"name":43,"class":6},1]