[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371514":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":32,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":85,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University of North Carolina, Chapel Hill","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Dentofacial Disharmony Patients",null,"Dentofacial disharmony patients who are seeking jaw surgery in UNC oral and maxillofacial surgery department and are seen in UNC orthodontic dentofacial disharmony clinic.",[13],"Other: Orthognathic surgery and Orthodontics",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Orthognathic surgery and Orthodontics","This study is observational. All subjects identified to participate will be undergoing orthognathic jaw surgery and orthodontic treatment.",[9],[20],{"name":21,"affiliation":22,"role":23},"Laura A Jacox, PhD, DMD, MS","Professor","PRINCIPAL_INVESTIGATOR",[25,29],{"name":21,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","847- 702-0988","ljacox@ad.unc.edu",{"name":30,"role":26,"phone":10,"phoneExt":10,"email":31},"Sherrill T Phillips, BS","sherrill_phillips@unc.edu",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"University of North Carolina","RECRUITING","Chapel Hill","North Carolina","27514","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-79.05584,35.9132,{"lat":45,"lon":44},[48,52],{"name":49,"role":26,"phone":50,"phoneExt":10,"email":51},"Laura A Jacox, DMD, PhD, MS","847-702-0988","LJacox@ad.unc.edu",{"name":49,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[56],{"name":57,"class":6},"North Carolina State University","100371514","orthognathic-speech-pathology-phonetic-contrasts-of-patients-with-dental-discrepancies-pre--and-post-treatment-analyses-100371514",false,"NCT04117360","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses","OSP","Inclusion Criteria:\n\n* Jaw surgery patient at UNC with a skeletal open bite, underbite or overjet greater than 5mm.\n* Age 15-40 years\n\nExclusion Criteria:\n\n* Hearing loss\n* Learned English as a second language\n* Significant regional accent, as characterized by a speech pathologist\n* Developmental delay, performing several grade levels below age bracket\n* history of craniofacial disorder\n* genetic syndrome associated with known craniofacial presentation\n* history of craniofacial trauma\n* history of prior craniofacial surgery (excluding extractions and dental procedures)\n* Jaw surgery without fixed orthodontic appliances","ALL","15 Years","40 Years",{"count":70,"type":71},180,"ESTIMATED","OBSERVATIONAL","The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but speech pathologists do not understand why. The investigators hypothesize that open bites and underbites prevent most patients from being able to pronounce words normally and surgical correction will lead to improvement in speech. Patients will be audio recorded speaking and patients' tongue gestures ultrasound recorded before and after their jaw surgeries to observe what changes occur in their speech and tongue movements.",[75,76,77,78,79,80,81,82,83,84],"Dentofacial Abnormalities","Dentofacial Deformities","Dentofacial Anomalies, Including Malocclusion","Malocclusion","Malocclusion in Children","Dentofacial Disharmony","Skeletal Malocclusion","Skeletal Malformation","Speech Sound Disorder","Speech Disorders",[80,86,83,87,88,89],"Skeletal malocclusion","Spectral Moment Analysis","Tongue Ultrasound","Orthognathic Surgery","2026-06-10",{"date":92,"type":93},"2026-06-12","ACTUAL",{"date":95,"type":93},"2019-09-11",{"date":97,"type":71},"2028-03",{"name":5,"class":6},1]