[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553402":3},{"organization":4,"armGroups":7,"interventions":39,"overallOfficials":63,"centralContacts":67,"locations":76,"responsibleParty":94,"collaborators":10,"id":96,"slug":97,"hasResults":98,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":10,"eligibilityCriteria":102,"healthyVolunteers":98,"sex":103,"minAge":104,"maxAge":10,"enrollmentInfo":105,"targetDuration":108,"studyType":109,"phases":10,"briefSummary":110,"conditions":111,"keywords":10,"overallStatus":79,"whyStopped":10,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"First Affiliated Hospital, Sun Yat-Sen University","OTHER",[8,14,19,24,29,34],{"label":9,"type":10,"description":11,"interventionNames":12},"Bypass group",null,"open bypass group",[13],"Procedure: open bypass group",{"label":15,"type":10,"description":16,"interventionNames":17},"BMS group","BMS (bare metal stent) group",[18],"Procedure: bare metal stent group",{"label":20,"type":10,"description":21,"interventionNames":22},"POBA group","POBA (plain old balloon angioplasty) group",[23],"Procedure: plain old balloon angioplasty group",{"label":25,"type":10,"description":26,"interventionNames":27},"DCB group","drug-coated balloon group",[28],"Procedure: drug-coated balloon group",{"label":30,"type":10,"description":31,"interventionNames":32},"DA group","DA (directional atherectomy) group",[33],"Procedure: directional atherectomy group",{"label":35,"type":10,"description":36,"interventionNames":37},"HR group","HR (hybrid repair) group",[38],"Procedure: hybrid repair group",[40,44,48,52,55,59],{"type":41,"name":11,"description":42,"armGroupLabels":43,"otherNames":10},"PROCEDURE","After heparinization, the target artery is clamped above and below the anastomosis. The target artery is dissected along the anterior wall, calcium portions or mural thrombus are removed. Graft (autologous or prosthetic graft) is cut obliquely and anastomosis suturing starts with distal angle. Next stage is tunnel creating for graft conduction.",[9],{"type":41,"name":45,"description":46,"armGroupLabels":47,"otherNames":10},"bare metal stent group","Bare metal stent implantation during the index procedure.",[15],{"type":41,"name":49,"description":50,"armGroupLabels":51,"otherNames":10},"plain old balloon angioplasty group","Only plain old balloon was used during the index procedure.",[20],{"type":41,"name":26,"description":53,"armGroupLabels":54,"otherNames":10},"Drug-coated balloon was used during the index procedure.",[25],{"type":41,"name":56,"description":57,"armGroupLabels":58,"otherNames":10},"directional atherectomy group","Directional atherectomy (with or without drug-coated balloon) during the index procedure.",[30],{"type":41,"name":60,"description":61,"armGroupLabels":62,"otherNames":10},"hybrid repair group","Femoral artery arteriotomy. Further execute a direct endarterectomy femoral artery and from the mouth of a hip artery. Arteriotomy of the femoral artery is closed with a vascular patch use (synthetic or biological). Endovascular revascularization followed.",[35],[64],{"name":65,"affiliation":5,"role":66},"Zilun Li","PRINCIPAL_INVESTIGATOR",[68,73],{"name":69,"role":70,"phone":71,"phoneExt":10,"email":72},"Haoliang Wu","CONTACT","18738957806","wu18738957806@126.com",{"name":65,"role":70,"phone":74,"phoneExt":10,"email":75},"13760871576","lizilun@mail.sysu.edu.cn",[77],{"facility":78,"status":79,"city":80,"state":81,"zip":82,"country":83,"countryCode":84,"cosmosGeoPoint":85,"geoPoint":90,"contacts":91},"The First Affiliated Hospital of Sun Yat-sen University","RECRUITING","Guangzhou","Guangdong","510030","China","CN",{"type":86,"coordinates":87},"Point",[88,89],113.25,23.11667,{"lat":89,"lon":88},[92],{"name":93,"role":70,"phone":74,"phoneExt":10,"email":75},"Zilun Li, Doctor",{"type":66,"investigatorFullName":65,"investigatorTitle":95,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Clinical Professor","100553402","outcome-and-improvement-of-different-treatment-in-arteriosclerosis-obliterans-100553402",false,"NCT06485622","Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans","Outcome and Improvement of Different Treatment in Arteriosclerosis Obliterans: a Prospective, Single-center, Observational Study","Inclusion Criteria:\n\n1. Age 18 years or older, gender is not limited.\n2. Patients diagnosed with arteriosclerosis obliterans.\n3. Rutherford stages 2-6.\n4. When there are multiple stenosis lesions, the treatment of the most severe lesion is included.\n5. Patients with at least one arterial occlusion ( iliac, femoral, popliteal, anterior tibial, posterior tibial, and\u002For peroneal artery) of the lower extremity were included.\n\nExclusion Criteria:\n\n1. Malignant tumor\n2. Alzheimer's disease\n3. Blood disease or bleeding tendency\n4. Heart Failure Grade III \\~ IV\n5. Pregnancy or lactation\n6. An above-knee-below-knee amputation has been performed\n7. Unable to accept therapeutic function tests\n8. Life expectancy is less than six months\n9. Combined with other diseases affecting walking\n10. Cardiovascular and cerebrovascular events occurred within 3 months, including non-fatal myocardial infarction, unstable angina, stable angina, non-fatal ischemic stroke and hemorrhagic stroke\n11. Patients with significant abnormal liver and renal function that the investigators judged to be clinically significant","ALL","18 Years",{"count":106,"type":107},400,"ESTIMATED","3 Years","OBSERVATIONAL","This study is a prospective, single-center, observational study. In this study, we aim to evaluate the clinical outcome and cost-effectiveness of different treatments of lower extremity arterial occlusive disease. It is expected to include about 400 patients diagnosed with lower extremity arterial occlusive disease in our center from July 2024 to July 2026. All enrolled patients will be followed for three years. All patients diagnosed with arteriosclerosis obliterans (ASO) and all treatment techniques were included in this study. The primary outcomes include the Efficacy and Safety End Points of each techniques.",[112],"Arteriosclerosis Obliterans","2025-08-05",{"date":115,"type":116},"2025-08-08","ACTUAL",{"date":118,"type":116},"2024-07-01",{"date":120,"type":107},"2029-07",{"name":5,"class":6},1]