[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100519410":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":50,"collaborators":52,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Guy's and St Thomas' NHS Foundation Trust","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Severe aortic stenosis",null,"Aortic valve area \\\u003C1.0 cm2\u002F\\\u003C0.6cm2\u002Fm2 or mean gradient \\>40mmHg or jet velocity \\>4.0 m\u002Fs.",[13],"Procedure: Transcatheter aortic valve implantation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Transcatheter aortic valve implantation","Intervention on aortic valve for severe aortic stenosis",[9],[21],{"name":22,"affiliation":23,"role":24},"Simon Redwood","King's College London","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Vitaliy Androshchuk","CONTACT","02071881083","Vitaliy.Androshchuk@gstt.nhs.uk",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":10},"Ariella Amar","02071887188",[35],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Guy's & St Thomas' NHS Foundation Trust, St Thomas' Hospital","London","United Kingdom","UK",{"type":41,"coordinates":42},"Point",[43,44],-0.12574,51.50853,{"lat":44,"lon":43},[47,48],{"name":32,"role":28,"phone":10,"phoneExt":10,"email":10},{"name":27,"role":49,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[53],{"name":23,"class":6},"100519410","outcome-prediction-in-patients-with-aortic-stenosis-after-tavi-100519410",false,"NCT06043180","Outcome Prediction in Patients With Aortic Stenosis After TAVI","Observational Study of Outcome Prediction in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) for Severe Symptomatic Aortic Stenosis (PREDICT-TAVI).","PREDICT-TAVI","Inclusion Criteria:\n\n* Patients with symptomatic severe aortic stenosis (AVA \\\u003C1.0 cm2\u002F\\\u003C0.6cm2\u002Fm2 or mean gradient \\>40mmHg or jet velocity \\>4.0 m\u002Fs).\n\nExclusion Criteria:\n\n* Extracardiac limitations of ambulatory exercise, cardiac rehab opt out, non-transfemoral TAVI, haemodynamic instability\u002Fcardiogenic shock, LVEF \\\u003C40%, poorly controlled AF, severe COPD, primary pulmonary hypertension, evidence of cardiac amyloid, more than moderate concomitant valvular heart disease other than aortic stenosis, previous sternotomy, permanent pacemaker implant, patients enrolled in another study where participation would involve deviation from either protocol.","ALL","18 Years",{"count":65,"type":66},69,"ESTIMATED","OBSERVATIONAL","This study will investigate changes right ventricular function and functional recovery metrics after transcatheter aortic valve implantation",[70],"Aortic Stenosis, Severe","NOT_YET_RECRUITING","2023-09-12",{"date":74,"type":75},"2023-09-21","ACTUAL",{"date":77,"type":66},"2023-10-01",{"date":79,"type":66},"2027-02-01",{"name":5,"class":6},1]