[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505739":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":33,"responsibleParty":346,"collaborators":348,"id":351,"slug":352,"hasResults":353,"nctId":354,"briefTitle":355,"officialTitle":355,"acronym":10,"eligibilityCriteria":356,"healthyVolunteers":353,"sex":357,"minAge":10,"maxAge":358,"enrollmentInfo":359,"targetDuration":10,"studyType":362,"phases":10,"briefSummary":363,"conditions":364,"keywords":366,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":373,"completionDateStruct":375,"leadSponsor":377,"locationsCount":378},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm A (Retrospective data)",null,"Participants who have undergone standard of care tisagenlecleucel therapy, Participants will received a questionnaire study using patient reported outcomes.",[13],"Other: Questionnaire for patients receiving therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Arm B (Prospective data)","Patients enrolled in ARM B will be asked to participate in the biological sample collection. Participants will received a questionnaire",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Questionnaire for patients receiving therapy","Questionnaires will be given (at baseline, 1, 3, 6, and 12 months post CAR infusion) including baseline demographics, individual\u002Ffamily and neighborhood socioeconomic data, measures of household material hardship (housing and transportation insecurity, household energy and food insecurity), barriers to care at the CAR T cell institution, as well as patient reported outcomes following Kymriah infusion.",[9,15],[24],{"name":25,"affiliation":5,"role":26},"Kara Davis, MD","PRINCIPAL_INVESTIGATOR",[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Khanh Nguyen","CONTACT","(650) 721-2372","khanhpn@stanford.edu",[34,52,66,78,91,105,119,132,146,160,174,188,202,216,230,247,263,277,291,304,318,332],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Banner University Medical Center - Tucson","RECRUITING","Tucson","Arizona","85719","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-110.92648,32.22174,{"lat":46,"lon":45},[49],{"name":50,"role":30,"phone":10,"phoneExt":10,"email":51},"Laurel Truscott","ltruscott@peds.arizona.edu",{"facility":53,"status":36,"city":54,"state":55,"zip":56,"country":40,"countryCode":41,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"City of Hope Comprehensive Cancer Center","Duarte","California","91010",{"type":43,"coordinates":58},[59,60],-117.97729,34.13945,{"lat":60,"lon":59},[63],{"name":64,"role":30,"phone":10,"phoneExt":10,"email":65},"Lindsey Murphy","lmurphy@coh.org",{"facility":5,"status":36,"city":67,"state":55,"zip":68,"country":40,"countryCode":41,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Palo Alto","94305",{"type":43,"coordinates":70},[71,72],-122.14302,37.44188,{"lat":72,"lon":71},[75,77],{"name":29,"role":30,"phone":76,"phoneExt":10,"email":32},"650-721-2372",{"name":25,"role":26,"phone":10,"phoneExt":10,"email":10},{"facility":79,"status":36,"city":80,"state":55,"zip":81,"country":40,"countryCode":41,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"UCSF (Benioff Children's)","San Francisco","94115",{"type":43,"coordinates":83},[84,85],-122.41942,37.77493,{"lat":85,"lon":84},[88],{"name":89,"role":30,"phone":10,"phoneExt":10,"email":90},"William Temple","william.temple@ucsf.edu",{"facility":92,"status":36,"city":93,"state":94,"zip":95,"country":40,"countryCode":41,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Nemours Children's Hospital","New Castle","Delaware","19803",{"type":43,"coordinates":97},[98,99],-75.56359,39.65948,{"lat":99,"lon":98},[102],{"name":103,"role":30,"phone":10,"phoneExt":10,"email":104},"Ellen Fraint","Ellen.Fraint@nemours.org",{"facility":106,"status":36,"city":107,"state":108,"zip":109,"country":40,"countryCode":41,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"University of Florida Health Science Center - Gainesville","Gainesville","Florida","32610",{"type":43,"coordinates":111},[112,113],-82.32483,29.65163,{"lat":113,"lon":112},[116],{"name":117,"role":30,"phone":10,"phoneExt":10,"email":118},"John Ligon","john.ligon@ufl.edu",{"facility":120,"status":36,"city":121,"state":108,"zip":122,"country":40,"countryCode":41,"cosmosGeoPoint":123,"geoPoint":127,"contacts":128},"Johns Hopkins All Children's Hospital","St. Petersburg","33701",{"type":43,"coordinates":124},[125,126],-82.67927,27.77086,{"lat":126,"lon":125},[129],{"name":130,"role":30,"phone":10,"phoneExt":10,"email":131},"Natalie Booth","nbooth3@jh.edu",{"facility":133,"status":36,"city":134,"state":135,"zip":136,"country":40,"countryCode":41,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Ann & Robert H. Lurie Children's Hospital of Chicago","Chicago","Illinois","60611",{"type":43,"coordinates":138},[139,140],-87.65005,41.85003,{"lat":140,"lon":139},[143],{"name":144,"role":30,"phone":10,"phoneExt":10,"email":145},"Kevin McNerney","kmcnerney@luriechildrens.org",{"facility":147,"status":36,"city":148,"state":149,"zip":150,"country":40,"countryCode":41,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Johns Hopkins University\u002FSidney Kimmel Cancer Center","Baltimore","Maryland","21231",{"type":43,"coordinates":152},[153,154],-76.61219,39.29038,{"lat":154,"lon":153},[157],{"name":158,"role":30,"phone":10,"phoneExt":10,"email":159},"Stacy Cooper","scoope30@jhmi.edu",{"facility":161,"status":36,"city":162,"state":163,"zip":164,"country":40,"countryCode":41,"cosmosGeoPoint":165,"geoPoint":169,"contacts":170},"Dana-Farber Cancer 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Louis","Missouri","63110",{"type":43,"coordinates":194},[195,196],-90.19789,38.62727,{"lat":196,"lon":195},[199],{"name":200,"role":30,"phone":10,"phoneExt":10,"email":201},"Thomas Pfeiffer","pthomas@wustl.edu",{"facility":203,"status":36,"city":204,"state":205,"zip":206,"country":40,"countryCode":41,"cosmosGeoPoint":207,"geoPoint":211,"contacts":212},"Children's Hospital at Montefiore","The Bronx","New York","10467",{"type":43,"coordinates":208},[209,210],-73.86641,40.84985,{"lat":210,"lon":209},[213],{"name":214,"role":30,"phone":10,"phoneExt":10,"email":215},"David Loeb","david.loeb@einsteinmed.edu",{"facility":217,"status":36,"city":218,"state":219,"zip":220,"country":40,"countryCode":41,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"Atrium Health Levine Cancer Institute","Charlotte","North Carolina","28262",{"type":43,"coordinates":222},[223,224],-80.84313,35.22709,{"lat":224,"lon":223},[227],{"name":228,"role":30,"phone":10,"phoneExt":10,"email":229},"Jeffrey 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MD","changb@ohsu.edu",{"name":262,"role":26,"phone":10,"phoneExt":10,"email":10},"BIll Chang, MD",{"facility":264,"status":36,"city":265,"state":266,"zip":267,"country":40,"countryCode":41,"cosmosGeoPoint":268,"geoPoint":272,"contacts":273},"Children's Hospital of Pittsburgh of UPMC","Pittsburgh","Pennsylvania","15224",{"type":43,"coordinates":269},[270,271],-79.99589,40.44062,{"lat":271,"lon":270},[274],{"name":275,"role":30,"phone":10,"phoneExt":10,"email":276},"Randy Windreich","Randy.Windreich@chp.edu",{"facility":278,"status":36,"city":279,"state":280,"zip":281,"country":40,"countryCode":41,"cosmosGeoPoint":282,"geoPoint":286,"contacts":287},"UT Southwestern\u002FSimmons Cancer Center-Dallas","Dallas","Texas","75235",{"type":43,"coordinates":283},[284,285],-96.80667,32.78306,{"lat":285,"lon":284},[288],{"name":289,"role":30,"phone":10,"phoneExt":10,"email":290},"Samuel John","samuel.john@utsouthwestern.edu",{"facility":292,"status":36,"city":293,"state":280,"zip":294,"country":40,"countryCode":41,"cosmosGeoPoint":295,"geoPoint":299,"contacts":300},"Cook Children's Medical Center","Fort Worth","76104",{"type":43,"coordinates":296},[297,298],-97.32085,32.72541,{"lat":298,"lon":297},[301],{"name":302,"role":30,"phone":10,"phoneExt":10,"email":303},"Holly Pacenta","holly.pacenta@cookchildrens.org",{"facility":305,"status":36,"city":306,"state":307,"zip":308,"country":40,"countryCode":41,"cosmosGeoPoint":309,"geoPoint":313,"contacts":314},"Saint Jude Children's Research Hospital","Fairfax","Virginia","22203",{"type":43,"coordinates":310},[311,312],-77.30637,38.84622,{"lat":312,"lon":311},[315],{"name":316,"role":30,"phone":10,"phoneExt":10,"email":317},"Swati Naik","swati.naik@stjude.org",{"facility":319,"status":36,"city":320,"state":321,"zip":322,"country":40,"countryCode":41,"cosmosGeoPoint":323,"geoPoint":327,"contacts":328},"Seattle Children's Hospital","Seattle","Washington","98105",{"type":43,"coordinates":324},[325,326],-122.33207,47.60621,{"lat":326,"lon":325},[329],{"name":330,"role":30,"phone":10,"phoneExt":10,"email":331},"Anurekha Hall","Anurekha.Hall@seattlechildrens.org",{"facility":333,"status":36,"city":334,"state":335,"zip":336,"country":40,"countryCode":41,"cosmosGeoPoint":337,"geoPoint":341,"contacts":342},"Medical College of Wisconsin","Milwaukee","Wisconsin","53226",{"type":43,"coordinates":338},[339,340],-87.90647,43.0389,{"lat":340,"lon":339},[343],{"name":344,"role":30,"phone":10,"phoneExt":10,"email":345},"Amy Moskop","amoskop@mcw.edu",{"type":347,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[349],{"name":350,"class":6},"The Pediatric Oncology Experimental Therapeutics Investigators' Consortium","100505739","outcomes-in-pediatric-and-young-adult-b-cell-malignancies-after-commercially-available-immunotherapy-100505739",false,"NCT05865301","Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy","Inclusion Criteria (Arm A)\n\n\\* Disease Status - B cell precursor acute lymphoblastic leukemia (ALL) or B cell lymphoma\n\nWho either:\n\n* Experienced refractory or relapsed disease, treated with standard chemotherapy, without immunotherapy treatment.\n\nOR\n\n* Previously undergone standard of care immunotherapy with FDA approved therapies, such as Kymriah™ (CTL019, tisagenlecleucel), blinatumomab or\n\n  * Age: Greater than or equal to 0 year of age and less than or equal to 26 years of age.\n\nInclusion Criteria (Arm B)\n\n* Disease Status - B cell precursor acute lymphoblastic leukemia (ALL) or B cell lymphoma\n* Age: Greater than or equal to 0 year of age and less than or equal to 26 years of age\n* Patients who are either:\n\n  * Undergoing evaluation for leukapheresis for planned standard of care tisagenlecleucel therapy, or planned for therapy with blinatumomab or inotuzumab. (Patients who received prior tisagenlecleucel, blinatumomab or inotuzumab on an established clinical trial and are now scheduled for commercial CAR, blinatumomab or inotuzumab therapy are also eligible) Or\n  * Experienced refractory or relapsed B cell precursor acute lymphoblastic leukemia (ALL) or B cell lymphoma\n* Ability to give informed consent. All subjects ≥ 18 years of age must be able to give informed consent or have legal authorized representative (LAR) (i.e. parent or guardian) to consent, if not in capacity to give consent independently. For subjects \\\u003C18 years old their LAR must give informed consent. Pediatric subjects will be included in age appropriate discussion and written assent will be obtained for those \\> 7 years of age, when appropriate, according to institutional procedures.","ALL","26 Years",{"count":360,"type":361},500,"ESTIMATED","OBSERVATIONAL","To use a consistent and standardized platform to retrospectively and prospectively study children and young adults with B cell malignancies receiving Immunotherapy, blinatumomab and\u002For inotuzumab ozogamicin.",[365],"Lymphoid Leukemia",[367,368],"PRWCC","Foresight","2026-06-02",{"date":371,"type":372},"2026-06-04","ACTUAL",{"date":374,"type":372},"2023-06-29",{"date":376,"type":361},"2038-12-31",{"name":5,"class":6},22]