[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632309":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":10,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":63,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Ohio State University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Bone graft patients",null,"Patients who are missing their upper back teeth and interested in having implant supported dental restorations, and who require direct sinus augmentation procedure on both right and left maxillary sinus prior to implant placement.",[13],"Device: Bone grafting on both sides",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Bone grafting on both sides","The surgical protocol is part of standard of care and will not be changed due to the study except the choice of the bone graft. Routinely (as the standard protocol), allograft (Straumann Allograft mineralized cortical granules \\[0.25-1mm\\]) is mixed with xenograft (bovine bone; Bio-Oss® small particles \\[0.25-1mm\\]) bone graft and placed into sinus. In this study, one randomly chosen sinus will receive this mixture (50:50 by volume) as the control. The other sinus on the same patient will receive a 50:50 (by volume) mixture of the same allograft with synthetic carbonate apatite (Cytrans® granules S size \\[0.3-0.6 mm\\]).",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Binnaz Leblebicioglu, DDS, MS, PhD","CONTACT","614-292-0371","leblebicioglu.1@osu.edu",[27],{"facility":28,"status":10,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"The Ohio State University College of Dentistry","Columbus","Ohio","43210","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-82.99879,39.96118,{"lat":38,"lon":37},[41],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Binnaz Leblebicioglu","Professor","100632309","outcomes-of-different-bone-graft-combinations-for-maxillary-sinus-augmentation-procedure-100632309",false,"NCT07512011","Outcomes of Different Bone Graft Combinations for Maxillary Sinus Augmentation Procedure","Maxillary Sinus Augmentation Through Lateral Window Technique: Outcomes of Different Bone Graft Combinations (MSA-BGC STUDY)","MSA-BGC","Inclusion Criteria:\n\n* Indication of bilateral sinus augmentation through lateral window technique to prepare maxillary right and left posterior edentulous sites for a single or multiple unit implant supported restorations.\n* Systemically healthy with controlled conditions\n* Periodontally healthy\u002Fcontrolled dentition\n* No known chronic and\u002For seasonal sinusitis\n* No previous ear, nose, throat, and sinus surgeries\n* Non-smokers\n* Willing to be treated with allograft, xenograft and\u002For synthetic bone graft materials\n\nExclusion Criteria:\n\n* 1\\. Indication of sinus augmentation through indirect techniques (≥5 mm initial alveolar ridge height from crest to maxillary sinus floor)\n* Implant placement surgery planned somewhere else\n* Implant placement planned at the time of sinus augmentation\n* Cases requiring major alveolar ridge augmentation concurrent with sinus augmentation\n* Cases requiring the use of a partial denture with buccal flange extension during the post-operative period\n* History of previously failed implant and\u002Fsinus augmentation procedures\n* History of tumors and\u002For radiation and\u002For chemotherapy\n* Uncontrolled systemic health problems and ENT\u002Fsinus concerns\n* Uncontrolled periodontal\u002Fdental problems\n* Intake of medications affecting wound or bone healing (e.g., corticosteroids, immunosuppressants, etc.)\n* Alcohol or drug abuse\n* Active smokers (patient should be a non-smoker for at least 1 year prior to sinus augmentation procedure)\n* Unable\u002Funwilling to follow post-operative instructions, rejecting to be treated with allograft, xenograft and\u002For synthetic bone graft materials\n* Unable\u002Funwilling to attend scheduled study visits\n* Participation in another clinical trial within 3 months prior to planned study entry","ALL",{"count":56,"type":57},10,"ESTIMATED","OBSERVATIONAL","This study investigates the outcomes of a surgical procedure that is performed to increase bone support at a future implant site on the upper back jaw area. This procedure requires placing bone graft material and\u002For substitutes into the maxillary sinus. The average healing time for the graft is about 6 months. Then, the site will be ready for dental implant. The study will compare healing outcomes of two types of bone graft mixtures used on the same patient (right and left upper jaw regions). The outcomes will be evaluated through clinical examination but also by studying the quality of the tissue through tissue biopsies obtained from grafted sites.",[61,62],"Bone Grafting","Sinus Lifting","NOT_YET_RECRUITING","2026-04-03",{"date":66,"type":67},"2026-04-06","ACTUAL",{"date":69,"type":57},"2026-06",{"date":71,"type":57},"2027-06",{"name":5,"class":6},1]