[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628074":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":55,"collaborators":10,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"St. Jude Children's Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Transition Cohort",null,"AYAs with CPS who have graduated from SJCRH and are followed longitudinally through surveys and assessments to evaluate health care transition outcomes.",[13,14,15],"Behavioral: Readiness Assessment","Behavioral: Transition Outcomes Survey A","Behavioral: Transition Outcomes Survey B",[17,22,26],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"BEHAVIORAL","Readiness Assessment","Electronic assessment administered 1 month post-graduation to evaluate transition preparedness.",[9],{"type":18,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Transition Outcomes Survey A","Administered at 1 and 3 years post-graduation to assess health care engagement and psychosocial outcomes.",[9],{"type":18,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Transition Outcomes Survey B","Administered at 5 and 8 years post-graduation to assess long-term outcomes and cancer surveillance adherence.",[9],[31],{"name":32,"affiliation":5,"role":33},"Melissa R Perrino, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":10,"email":38},"CONTACT","888-226-4343","referralinfo@stjude.org",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Memphis","Tennessee","38105","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-90.04898,35.14953,{"lat":51,"lon":50},[54],{"name":32,"role":36,"phone":37,"phoneExt":10,"email":38},{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100628074","outcomes-of-health-care-transition-for-aya-with-a-cancer-predisposition-100628074",false,"NCT07456904","Outcomes of Health Care Transition for AYA With a Cancer Predisposition","OnTRAC","Inclusion Criteria:\n\n* Participants are ≥18 years of age\n* Participants with a molecular or clinical diagnosis of a Cancer Predisposition Syndrome (CPS) who are graduating or have graduated from SJCRH.\n* Participants who were a patient of the SJCRH Cancer Predisposition Clinic for at least 3 years before graduating from SJCRH\n* Participants who require cancer\u002Ftumor surveillance within 1 year after graduation from SJCRH. Required cancer\u002Ftumor surveillance in adulthood is defined as having a CPS with expert guidelines recommending cancer\u002Ftumor surveillance in adulthood\n* Participants fluent in English.\n\nExclusion Criteria:\n\n* Participants who are not their own legal medical decision-maker.","ALL","18 Years",{"count":67,"type":68},56,"ESTIMATED","OBSERVATIONAL","This observational study evaluates whether adolescents and young adults (AYAs) with a cancer predisposition syndrome (CPS) establish and maintain adult health care and continue CPS-specific cancer surveillance after graduating from pediatric care at St. Jude Children's Research Hospital (SJCRH). Participants will complete a Readiness Assessment and periodic surveys over 8 years post-graduation.\n\nPrimary Objectives\n\n* To evaluate whether adolescents and young adults (AYAs) with a cancer predisposition syndrome (CPS) report they have established care with adult health care providers and pursue CPS-specific cancer surveillance within 1-year post-graduation from SJCRH.\n* To evaluate whether AYAs with CPS report they maintain care with adult health care providers and continue CPS-specific cancer surveillance 3 years post-graduation from SJCRH.\n\nExploratory Objectives:\n\n* To evaluate whether AYAs with CPS report they continue to maintain care with adult health care providers and complete CPS-specific cancer surveillance longitudinally 5 years and 8 years post-graduation from St. Jude Children's Research Hospital (SJCRH).\n* To examine clinical correlates of establishing care with adult providers and initiating CPS-specific cancer surveillance post-graduation from SJCRH.\n* To identify the tumors diagnosed in AYAs with CPS after they graduate from SJCRH and determine how these tumors were identified (i.e., through specific surveillance tests or based on symptoms).\n* To identify barriers and facilitators AYAs face when establishing and maintaining adult health care and pursuing CPS-specific cancer surveillance.",[72],"Genetic Predisposition",[74,75,76,77],"Genetic cancer risk","Cancer predisposition","Health care transition","Adolescent and young adult oncology","2026-06-16",{"date":80,"type":81},"2026-06-18","ACTUAL",{"date":78,"type":81},{"date":84,"type":68},"2037-11",{"name":5,"class":6},1]