[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644977":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":39,"locations":47,"responsibleParty":71,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":26,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":26,"enrollmentInfo":87,"targetDuration":26,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"VR-Assisted Overground Gait Therapy","EXPERIMENTAL","Participants in the treatment group (VG-AOGT) will engage in gait training within a newly developed immersive virtual reality (VR) environment. This setup features self-propelled overground walking influenced by three different virtual environments designed to mimic real-world conditions. The immersive technology used is HTC VIVE Focus Vision, enabling participants to practice walking in real-world environments and gait tasks.",[13],"Device: Walk-over-Ground",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional Treadmill-Based VR Gait Therapy","ACTIVE_COMPARATOR","Participants in the control group (VR-CTGT) will engage in gait training using C-Mill VR+ technology, which involves treadmill-assisted walking on a treadmill while interacting with less immersive virtual scenarios presented on screens.",[19],"Device: C-Mill VR+ by Motek",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Walk-over-Ground","Fully-immersive, real-world environments, overground gait therapy",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"C-Mill VR+ by Motek","Semi-immersive, game-like environments, treadmill gait therapy",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Hee-Tae Jung, Ph.D.","Indiana University, Luddy School of Informatics, Computing, and Engineering","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":38,"role":35},"Peter Altenburger, Ph.D., PT","Indiana University, School of Health & Human Sciences; Indiana University Health, Center for Advanced Neurorehabilitation",[40,44],{"name":37,"role":41,"phone":42,"phoneExt":26,"email":43},"CONTACT","317-278-0703","paltenbu@iu.edu",{"name":33,"role":41,"phone":45,"phoneExt":26,"email":46},"317-278-1285","heetjung@iu.edu",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Indiana University Health, Neurorehabilitation & Robotics","RECRUITING","Indianapolis","Indiana","46202","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-86.15804,39.76838,{"lat":60,"lon":59},[63,64,68,69],{"name":37,"role":41,"phone":42,"phoneExt":26,"email":43},{"name":65,"role":41,"phone":66,"phoneExt":26,"email":67},"Kathryn Gyves, PT, DPT, NCS, CSRS, AVPT, CBIS","317-963-7050","kgyves@iuhealth.org",{"name":37,"role":35,"phone":26,"phoneExt":26,"email":26},{"name":33,"role":70,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":35,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Hee-Tae Jung","Assistant Professor, Health Informatics",[75],{"name":76,"class":77},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100644977","overground-virtual-reality-vr-gait-rehabilitation-for-stroke-100644977",false,"NCT07676578","Overground Virtual Reality (VR) Gait Rehabilitation for Stroke","Investigating the Feasibility and Translational Therapeutic Benefits of Overground, Fully Immersive Virtual Reality (VR) Gait Rehabilitation Therapies for Stroke Survivors","Inclusion Criteria:\n\n* Diagnosis: Anischemic or hemorrhagic stroke verified by imaging, confirmed by the patient's physician, and 1-6 months post-stroke (subacute phase)\n* Motor Impairment Level: Functional Ambulation Category (FAC) 3-5, showing moderate impairment while still allowing safe participation in gait tasks.\n* Cognitive Function: Mini-Mental State Examination (MMSE) score ≥ 24 or Montreal Cognitive Assessment (MoCA) score \\>= 20, indicating sufficient cognitive function to participate in the study.\n* Exercise Clearance: Approval from a physician for participation in exercise- and VR-based interventions.\n* Rehabilitation Need: 10-Meter Walk Test \\\u003C1.0 m\u002Fs, as timed by a PT during screening, indicating a need for functional rehabilitation.\n* Consent: Must be able to provide informed consent for themselves.\n\nExclusion Criteria:\n\n* Participants with uncontrolled cardiovascular, orthopedic, or metabolic conditions or unstable medication regimens that could interfere with their participation in the study.\n* Any comorbidity that could interfere with walking or gait training.\n* Participation in robot- or VR-assisted gait training within the last 6 months.\n* Intolerance to virtual reality environments or motion simulation.\n* Severe cognitive, visual, or hearing impairments where the participant cannot follow the therapist's instructions.\n* Any other condition deemed unsafe or confounding by investigator, such as pre-existing neurological conditions unrelated to stroke (e.g. Parkinson's, multiple sclerosis), unmanaged pain medications, or acute medical events during the screening period (e.g. recurrent stroke, hospitalization).\n* Individuals who score a 12 or higher on the Disability Rating Scale.\n* Recent Therapy: Participants should not have received physical therapy (PT) within the last month.","ALL","18 Years",{"count":88,"type":89},30,"ESTIMATED","INTERVENTIONAL",[92],"NA","The purpose of this study is to evaluate a new virtual reality (VR)-based rehabilitation program designed to help stroke survivors improve their walking abilities in real-world settings. By comparing immersive VR-assisted overground gait therapy to contemporary non-immersive, treadmill-based VR therapy (i.e., C-Mill), the investigators aim to determine its effectiveness in enhancing mobility and quality of life for stroke survivors.",[95],"Stroke",[97,98,95],"Gait Training","Virtual Reality","2026-06-29",{"date":101,"type":102},"2026-07-01","ACTUAL",{"date":104,"type":89},"2026-08",{"date":106,"type":89},"2027-08",{"name":5,"class":6},1]