[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589828":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":34,"centralContacts":38,"locations":49,"responsibleParty":66,"collaborators":43,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":43,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":43,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":43,"overallStatus":89,"whyStopped":43,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A","ACTIVE_COMPARATOR","About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to early morning air for 60 minutes (Early morning air\" refers to the fresh, cool air found during the early hours of the day, (it's around 5-7 am, just before or after sunrise).",[13],"Biological: Oxygen Therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to oxygen by non- rebreather mask (We choose oxygen by non- rebreather mask and no other ways of oxygen delivery system because it is the only available cost effective and non-invasive oxygen delivery device that can provide high oxygen flow that is close enough to HBOT)",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group C","About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to hyperbaric oxygen therapy in a hyperbaric chamber at 2.5 ATA (atmospheres absolute) for 60 minutes per session (we choose 2.5 ATA hyperbaric oxygen therapy in a hyperbaric chamber (atmospheres absolute) for 60 minutes per session.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Group D","About 20 patients suffering from Diabetic kidney disease and will receive standard diabetes and Diabetic kidney disease management",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BIOLOGICAL","Oxygen Therapy","1. To evaluate the effect of oxygen therapy (hyperbaric oxygen and oxygen by non- rebreather mask) and early morning air on proteinuria in patients with diabetic kidney disease.\n2. To evaluate the effect of oxygen therapy (hyperbaric oxygen and oxygen by non- rebreather mask) and early morning air on glycated haemoglobin in patients with diabetic kidney disease.\n3. Comparing the effects of oxygen therapy (hyperbaric oxygen and oxygen by non- rebreather mask), early morning air exposure, and standard care on kidney function",[9,15,19,23],[33],"Standard diabetes and CKD management",[35],{"name":36,"affiliation":5,"role":37},"Ashraf Anwar Thabet, Professor","STUDY_CHAIR",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Hodna Abdullah Ahmed, MSC","CONTACT","+201009468368",null,"hodnaabdullah@med.aun.edu.eg",{"name":46,"role":41,"phone":47,"phoneExt":43,"email":48},"Ashraf Anwar Thabet, professor","+201062879221","ashrafshazly@aun.edu.eg",[50],{"facility":51,"status":43,"city":52,"state":43,"zip":43,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Assuit University hospitals","Asyut","Egypt","EG",{"type":56,"coordinates":57},"Point",[58,59],31.18368,27.18096,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":43,"email":65},"Mohamed Faisal Adawy, Lecturer","+201001244126","DR-m.faisal85m@aun.edu.eg",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"PRINCIPAL_INVESTIGATOR","Hodna Abdullah Ahmed","Resident of Internal medicine","100589828","oxygen-therapy-in-diabetic-kidney-disease-100589828",false,"NCT06959485","Oxygen Therapy in Diabetic Kidney Disease","Oxygen Therapy in Diabetic Kidney Disease and Its Effect on Proteinuria and Blood Glucose Level","Inclusion Criteria:\n\n\\- Diabetic male and female patients aged \\> 18 yrs with diabetic kidney disease (eGFR 30-90 mL\u002Fmin\u002F1.73m² and proteinuria \\>300 mg\u002Fday)\n\nExclusion Criteria:\n\n* Age \\\u003C 18 yrs\n* Cardiovascular disease (thorough assessment of the patient's medical history (symptoms suggestive of CVD (e.g., chest pain, shortness of breath, fatigue), family history of CVD and risk factors (e.g., hypertension, hyperlipidemia, smoking). Physical Examination including blood pressure measurement, auscultation of heart sounds and assessment of peripheral pulses. Additional Diagnostic Tests: Stress test (stress ECG and stress echocardiography): Evaluate cardiac function under stress, which can help detect coronary artery disease or other CVD.\n* Chronic lung disease (COPD, pulmonary fibrosis …\n* Other chronic disease affecting kidney function (lupus nephritis).\n* Pregnancy or lactation.","ALL","10 Years","17 Years",{"count":81,"type":82},80,"ESTIMATED","INTERVENTIONAL",[85],"NA","Diabetic kidney disease (DKD) is the most significant cause of end-stage kidney disease (ESKD). Albuminuria, evolving from microalbuminuria to nephrotic-range proteinuria, is a clinical hallmark of diabetic nephropathy (DN). It develops in about a third of diabetic patients and is considered an independent risk factor in the progression of DN and for all-cause mortality.",[88],"Diabetic Kidney Disease","NOT_YET_RECRUITING","2025-04-28",{"date":92,"type":93},"2025-05-06","ACTUAL",{"date":95,"type":82},"2025-08-01",{"date":97,"type":82},"2026-08-10",{"name":5,"class":6},1]