[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595674":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":34,"responsibleParty":51,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":32,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":32,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":83,"whyStopped":32,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Universidade Federal do Paraná","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ozone therapy on endometriosis","EXPERIMENTAL","The participants will undergo anamnesis, including clinical and epidemiological aspects for this research, including the capture of thermographic images. The participants will have previously undergone the transvaginal ultrasound examination; These participants will undergo 10 sessions, within the pre-established protocol with ozone. The selected participants will be allocated into two groups: Group A (ozone therapy) and Group B (control group - conventional treatment). Each group will consist of 20 participants. - Group A (Ozone Therapy): The participants in this group will undergo ozone therapy sessions, according to the established protocol, and will receive treatment in the pelvic cavity with an initial injection of ozonated water, followed by an injection of ozone gas. The application of ozone will be done according to standardized and referenced techniques. - Group B (Clinical treatment): The participants in this group will be monitored to compare the results.",[13],"Other: Ozone therapy",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Ozone therapy","The study also aims to analyze the efficacy of ozone therapy in participants affected by endometriosis, enriching the knowledge base in the field of women's health\u002Fgynecology. The expected results will contribute to improving current therapeutic approaches, informing clinical decisions and encouraging future research. Understanding the technique and its clinical applicability will help health professionals to offer personalized and effective treatments. In addition, the insights obtained can direct new investigations, such as the optimization of protocols or the exploration of innovative therapeutic combinations for even more satisfactory results. Based on the literature review and the biochemical properties of both techniques (ozone therapy and clinical approach), it may be possible that one of the approaches demonstrates a statistically superior advantage over the other. In addition, the research aims to investigate whether the quality of life of these participants will improve and i",[9],[20,21],"thermography","ultrasound",[23],{"name":24,"affiliation":25,"role":26},"Henrique Cunha Carvalho, PhD. Dr.","UTFPR","STUDY_CHAIR",[28],{"name":29,"role":30,"phone":31,"phoneExt":32,"email":33},"Fernanda Luiza Ferraz, Physiotherapist \u002F Therapist","CONTACT","55 41 99971-1737",null,"fernandaferraz88@gmail.com",[35],{"facility":36,"status":32,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Clínica Fernanda Ferraz - Fisioterapia Integrativa LTDA","Curitiba","Paraná","80240-100","Brazil","BR",{"type":43,"coordinates":44},"Point",[45,46],-49.27306,-25.42778,{"lat":46,"lon":45},[49],{"name":29,"role":30,"phone":50,"phoneExt":32,"email":33},"55 41 999711737",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Henrique Cunha Carvalho","Evaluation of the effects of ozone therapy on endometriosis",[56],{"name":57,"class":58},"Philozon Geradores de Ozonio LTDA","INDUSTRY","100595674","ozone-therapy-for-women-with-endometriosis-100595674",false,"NCT07035522","Ozone Therapy for Women With Endometriosis","Evaluation of the Effects of Ozone Therapy on Endometriosis","Inclusion Criteria:\n\n* Women with a clinical diagnosis of endometriosis (ultrasonography \u002F transvaginal exam)\n* 25-45 years old\n\nExclusion Criteria:\n\n* Pregnancy\n* G6PD positive\n* Addicted\n* HIV and hepatitis positive\n* Cancer\n* Anticoagulant sensitive\n* Endometrial surgery history","FEMALE","25 Years","45 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","To evaluate the action of ozone therapy as an adjuvant treatment in patients with endometriosis. Secondary Objective: To evaluate the efficacy of ozone therapy for pelvic analgesia in women with endometriosis; To compare the imaging diagnostic techniques of transvaginal ultrasound with infrared thermography in the pre-treatment (before), fourth, seventh and post-treatment (10th session) periods; To evaluate the application of the consolidated questionnaire (EHP-30) in the changes in the quality of life of the participants immediately after the intervention.",[77,78,79],"Endometriosis","Ozone Therapy","Thermography",[81,82,21,20],"ozone","ozone therapy","NOT_YET_RECRUITING","2025-06-16",{"date":86,"type":87},"2025-06-25","ACTUAL",{"date":89,"type":71},"2025-06-18",{"date":91,"type":71},"2025-12-20",{"name":5,"class":6},1]