[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614408":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":18,"responsibleParty":36,"collaborators":7,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":40,"sex":46,"minAge":47,"maxAge":7,"enrollmentInfo":48,"targetDuration":51,"studyType":52,"phases":7,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":68,"whyStopped":7,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Ilya Lukin","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Ilya B. Lukin, MD, PhD","Principal Investigator","PRINCIPAL_INVESTIGATOR",[14],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","+7 906 656 2630","prlukin@gmail.com",[19],{"facility":20,"status":7,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Tver State Medical University Clinical Center","Tver'","Tver Oblast","170000","Russia","RU",{"type":27,"coordinates":28},"Point",[29,30],35.90057,56.85836,{"lat":30,"lon":29},[33,35],{"name":10,"role":15,"phone":34,"phoneExt":7,"email":17},"+79066562630",{"name":10,"role":12,"phone":7,"phoneExt":7,"email":7},{"type":37,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100614408","pace-af-prospective-analysis-of-cardiac-electrostimulation-and-atrial-fibrillation-100614408",false,"NCT07279207","PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation","Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation (PACE-AF)","PACE-AF","Inclusion Criteria:\n\n* • Age ≥ 18 years\n\n  * Implantation of a dual-chamber permanent pacemaker\n  * Ability to provide informed consent\n  * Willingness to participate in long-term follow-up\n\nExclusion Criteria:\n\n* • Single-chamber pacemaker or Cardiac Resynchronization Therapy device at baseline\n\n  * Life expectancy \\\u003C 1 year due to non-cardiac comorbidities\n  * Inability to comply with follow-up visits or device interrogation\n  * Participation in another clinical trial that could interfere with study endpoints","ALL","18 Years",{"count":49,"type":50},500,"ESTIMATED","3 Years","OBSERVATIONAL","PACE-AF is a prospective, observational patient registry designed to evaluate the impact of pacemaker algorithms on atrial fibrillation (AF) incidence, progression, and clinical outcomes in patients implanted with dual-chamber pacemakers. The registry aims to include 400-500 patients with longitudinal follow-up. Primary outcomes are progression to permanent AF and all-cause mortality. Secondary outcomes include quality of life, hospitalization, and cardiovascular events.",[55,56,57],"Atrial Fibrillation","Sick Sinus Syndrome","Atrioventricular Block",[59,60,61,62,63,64,65,66,67],"Pacemaker","Dual-chamber pacing","Pacemaker algorithms","Conduction system pacing","His bundle pacing","Left bundle branch pacing","Catheter ablation","Cryoablation","Arrhythmia prevention","NOT_YET_RECRUITING","2025-11-30",{"date":71,"type":72},"2025-12-12","ACTUAL",{"date":74,"type":50},"2025-12",{"date":76,"type":50},"2028-12",{"name":5,"class":6},1]