[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496729":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":42,"responsibleParty":173,"collaborators":10,"id":175,"slug":176,"hasResults":177,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":10,"eligibilityCriteria":181,"healthyVolunteers":177,"sex":182,"minAge":183,"maxAge":10,"enrollmentInfo":184,"targetDuration":10,"studyType":187,"phases":10,"briefSummary":188,"conditions":189,"keywords":190,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":194,"lastUpdatePostDateStruct":195,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":203},{"fullName":5,"class":6},"Istituti Clinici Scientifici Maugeri SpA","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Parkinson Disease",null,"Patients affected by Parkinson's disease admitted for rehabilitation in Maugeri Clinical Scientific Institutes",[13,14],"Other: Rehabilitation","Other: Administration of Clinical scales",{"label":16,"type":10,"description":17,"interventionNames":18},"Multiple System Atrophy","Patients affected by Multiple System Atrophy admitted for rehabilitation in Maugeri Clinical Scientific Institutes",[13,14],[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Rehabilitation","All patients included in the study will undergo a basic evaluation with a neurological examination, a rehabilitation program to improve strength, coordination, balance, endurance, and the ability to perform activities of daily life.",[16,9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Administration of Clinical scales","All patients included in the study will be evaluated by clinical scales assessing the disease stage, clinical severity, freezing, motor and non-motor impairment, cognitive impairment, depression, quality of life, autonomic dysfunction, pain.",[16,9],[29],{"name":30,"affiliation":31,"role":32},"Maria Nolano, MD, PhD","Isituti Clinici Scientifici Maugeri SpA SB - IRCCS of Telese Terme","PRINCIPAL_INVESTIGATOR",[34,38],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","+390824909257","maria.nolano@icsmaugeri.it",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Giuseppe Caporaso","+390824909645","giuseppe.caporaso@icsmaugeri.it",[43,61,76,91,106,121,136,150,163],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"ICS Maugeri - IRCCS of Telese Terme","RECRUITING","Telese Terme","Benevento","82037","Italy","IT",{"type":52,"coordinates":53},"Point",[54,55],14.52681,41.21752,{"lat":55,"lon":54},[58],{"name":59,"role":35,"phone":36,"phoneExt":10,"email":60},"Vincenzo Provitera, MD","vincenzo.provitera@icsmaugeri.it",{"facility":62,"status":45,"city":63,"state":64,"zip":65,"country":49,"countryCode":50,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"ICS Maugeri - Lumezzane","Lumezzane","Brescia","25065",{"type":52,"coordinates":67},[68,69],10.26487,45.64789,{"lat":69,"lon":68},[72],{"name":73,"role":35,"phone":74,"phoneExt":10,"email":75},"Diego Ghianda, MD","0308253186","diego.ghianda@icsmaugeri.it",{"facility":77,"status":45,"city":78,"state":79,"zip":80,"country":49,"countryCode":50,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"ICS Maugeri - Castelgoffredo","Castel Goffredo","Mantova","46042",{"type":52,"coordinates":82},[83,84],10.473,45.29403,{"lat":84,"lon":83},[87],{"name":88,"role":35,"phone":89,"phoneExt":10,"email":90},"Giuliana Vezzadini, MD","037677471","giuliana.vezzadini@icsmaugeri.it",{"facility":92,"status":45,"city":93,"state":94,"zip":95,"country":49,"countryCode":50,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"ICS Maugeri - Mistretta","Mistretta","Messina","98073",{"type":52,"coordinates":97},[98,99],14.3578,37.92823,{"lat":99,"lon":98},[102],{"name":103,"role":35,"phone":104,"phoneExt":10,"email":105},"Paolo Volanti, MD","0921389574","paolo.volanti@icsmaugeri.it",{"facility":107,"status":45,"city":108,"state":109,"zip":110,"country":49,"countryCode":50,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"ICS Maugeri - Veruno","Veruno","Novara","28010",{"type":52,"coordinates":112},[113,114],8.52863,45.68887,{"lat":114,"lon":113},[117],{"name":118,"role":35,"phone":119,"phoneExt":10,"email":120},"Giorgio Maggioni, MD","0322884711","giorgio.maggioni@icsmaugeri.it",{"facility":122,"status":45,"city":123,"state":124,"zip":125,"country":49,"countryCode":50,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"ICS Maugeri - Montescano","Montescano","Pavia","27040",{"type":52,"coordinates":127},[128,129],9.28366,45.03196,{"lat":129,"lon":128},[132],{"name":133,"role":35,"phone":134,"phoneExt":10,"email":135},"Cira Fundarò, MD","0385247268","cira.fundaro@icsmaugeri.it",{"facility":137,"status":45,"city":138,"state":10,"zip":139,"country":49,"countryCode":50,"cosmosGeoPoint":140,"geoPoint":144,"contacts":145},"ICS Maugeri - Milano","Milan","20138",{"type":52,"coordinates":141},[142,143],12.59836,42.78235,{"lat":143,"lon":142},[146],{"name":147,"role":35,"phone":148,"phoneExt":10,"email":149},"Beatrice De Maria, Eng","0250725260","beatrice.demaria@icsmaugeri.it",{"facility":151,"status":45,"city":124,"state":10,"zip":152,"country":49,"countryCode":50,"cosmosGeoPoint":153,"geoPoint":157,"contacts":158},"ICS Maugeri - Pavia Boezio","27100",{"type":52,"coordinates":154},[155,156],9.15917,45.19205,{"lat":156,"lon":155},[159],{"name":160,"role":35,"phone":161,"phoneExt":10,"email":162},"Marianna Loi, MD","+3903825931","marianna.loi@icsmaugeri.it",{"facility":164,"status":45,"city":124,"state":10,"zip":152,"country":49,"countryCode":50,"cosmosGeoPoint":165,"geoPoint":167,"contacts":168},"ICS Maugeri - Pavia",{"type":52,"coordinates":166},[155,156],{"lat":156,"lon":155},[169],{"name":170,"role":35,"phone":171,"phoneExt":10,"email":172},"Isabella Springhetti, MD","+390382592621","isabella.springhetti@icsmaugeri.it",{"type":174,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100496729","pain-and-autonomic-symptoms-in-parkinsons-disease-and-atypical-parkinsonisms-100496729",false,"NCT05748028","Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms","Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms: Identification of Predictive Patterns of Rehabilitation Outcome and Evaluation of the Impact on Quality of Life","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's Disease or Multiple System Atrophy according to current international criteria (Gilman S et al, 2008; Postuma RB et al. 2015).\n* Mini-Mental State Examination score at least 10\n\nExclusion Criteria:\n\n* vascular or pharmacological parkinsonism\n* diabetes mellitus\n* hepatic or renal dysmetabolism,\n* hypothyroidism or hyperthyroidism\n* assumption of potentially neurotoxic drugs","ALL","18 Years",{"count":185,"type":186},280,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers.\n\nThe main aims are:\n\nEvaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales.\n\nResearchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.",[9,16],[191,192,193],"pain","autonomic symptoms","rehabilitation","2026-04-14",{"date":196,"type":197},"2026-04-17","ACTUAL",{"date":199,"type":197},"2019-06-15",{"date":201,"type":186},"2026-12-30",{"name":5,"class":6},9]