[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639599":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":16,"locations":26,"responsibleParty":42,"collaborators":7,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":7,"enrollmentInfo":54,"targetDuration":7,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":28,"whyStopped":7,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Centre Hospitalier Princesse Grace","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"No Intervention: Observational Cohort","Standard rapid sequence induction according to SFAR guidelines, with additional non-invasive ANI monitoring via cutaneous pectoral electrodes. No intervention beyond routine care; induction drug choice (hypnotic, opioid, neuromuscular blocker) at the discretion of the anesthesiologist.",[13],{"name":14,"affiliation":5,"role":15},"Remy WIDEHEM, MD","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":7,"email":21},"Remy WIDEHEM","CONTACT","+377 97 98 99 00","remy.widehem@chpg.mc",{"name":23,"role":19,"phone":24,"phoneExt":7,"email":25},"Celine DUGOURD","+377 97 98 84 29","recherche.clinique@chpg.mc",[27],{"facility":5,"status":28,"city":29,"state":7,"zip":30,"country":29,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Monaco","98000","MC",{"type":33,"coordinates":34},"Point",[35,36],7.42145,43.73718,{"lat":36,"lon":35},[39],{"name":40,"role":19,"phone":41,"phoneExt":7,"email":21},"Rémy WIDEHEM, MD","0037797989900",{"type":43,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100639599","pain-assessment-during-rapid-sequence-induction-100639599",false,"NCT07588165","Pain Assessment During Rapid Sequence Induction","Nociception Assessment During Rapid Sequence Induction: A Prospective Observational Study of Practices and Complications - The NARSI Study","NARSI","Inclusion Criteria:\n\n* Age \\>= 18 years\n* Patient requiring tracheal intubation after rapid sequence induction in the visceral surgery operating room\n* Pain monitoring by Analgesia Nociception Index (ANI) as part of general anesthesia\n\nExclusion Criteria:\n\n* Patient with atrial fibrillation at the time of intubation following rapid sequence induction\n* Patient on long-term beta-blocker therapy","ALL","18 Years",{"count":55,"type":56},150,"ESTIMATED","OBSERVATIONAL","Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception using the Analgesia Nociception Index (ANI) during this procedure.\n\nThis monocentric prospective observational study aims to describe the impact of RSI on pain measured by ANI, and to explore early complications (desaturation, hypotension, regurgitation) and factors associated with pain and complications. 150 patients undergoing RSI in the visceral surgery operating room at CHPG Monaco will be analyzed.",[60,61,62,63],"Rapide Sequence Induction","Tracheal Intubation","Nociception","General Anesthesia",[65,66,67,68,69,70],"Analgesia Nociception Index (ANI)","Rapid Sequence Induction (RSI)","Pain monitoring","Tracheal intubation","Hemodynamic response","General anesthesia","2026-05-22",{"date":73,"type":74},"2026-05-27","ACTUAL",{"date":76,"type":74},"2026-05-21",{"date":78,"type":56},"2028-05",{"name":5,"class":6},1]