[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621049":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":26,"centralContacts":35,"locations":42,"responsibleParty":61,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":26,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University Hospital, Toulouse","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Idiopathic REM sleep Behavior disorder (iRBD) Group","EXPERIMENTAL","Patients who have an idiopathic REM sleep Behavior Disorder",[13,14,15],"Other: Thermo test pain","Other: Pain questionnaires","Other: No motors symptoms evaluations",{"label":17,"type":18,"description":19,"interventionNames":20},"Idiopathic REM Sleep Bhavior Disorder (iRBD) + narcolepsy type 1","ACTIVE_COMPARATOR","patients who have an iRBD and who have type 1 narcolepsy",[13,14,15],[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Thermo test pain","Patients will undergo a pain test, also called a thermotest, which consists of determining pain thresholds using a thermometer applied to the hand.",[17,9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Pain questionnaires","Patients will complete various questionnaires about pain",[17,9],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"No motors symptoms evaluations","Patients will complete questionnaires",[17,9],[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Christine BREFEL COURBON","CONTACT","05 61 77 60 39","+33","christine.brefel-courbon@univ-tlse3.Fr",[43],{"facility":44,"status":45,"city":46,"state":26,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Centre Expert Parkinson Hôpital Pierre Paul Riquet Place du Docteur Baylac","RECRUITING","Toulouse","31059","France","FR",{"type":51,"coordinates":52},"Point",[53,54],1.44367,43.60426,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":59,"phoneExt":40,"email":60},"Emeline Muller","05 61 77 87 07","muller.E@chu-toulouse.Fr",{"type":62,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100621049","pain-assessment-in-patients-with-idiopathic-rapid-eye-movement-rem-sleep-behaviour-disorder-100621049",false,"NCT07365566","Pain Assessment in Patients With Idiopathic Rapid Eye Movement (REM) Sleep Behaviour Disorder","Pain Assessment in Patients With Idiopathic REM Sleep Behaviour Disorder","PAIN-iRBD","Inclusion criteria:\n\n* Diagnosed with iRBD confirmed by polysomnography;\n* No clinical diagnosis of Parkinson's disease or other diagnosis of neurodegenerative disease;\n* Ability to understand and complete study procedures and questionnaires;\n\nControl group:\n\n* Diagnosed with narcolepsy type 1;\n* Coexisting REM sleep behavior disorder confirmed by polysomnography;\n* Ability to understand and complete study procedures and questionnaires;\n\nExclusion Criteria:\n\n* Diagnosed Parkinson's Disease, dementia with Lewy bodies or multiple system atrophy;\n* Severe depression according to Diagnostic and Statistical Manual of Mental Disorders (DSM V);\n* Inability to complete study procedures or questionnaires.","ALL","18 Years",{"count":74,"type":75},24,"ESTIMATED","INTERVENTIONAL",[78],"NA","Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, with over 12 million patients expected globally by 2040. The disease is currently diagnosed at the appearance of motor symptoms, but by then, over 60% of striatal dopaminergic neurons have already been destroyed. Prodromal symptoms such as idiopathic REM Sleep Behavior Disorder (iRBD), anosmia, mood disorders and constipation appear earlier and are listed as criteria for a prodromal PD diagnosis. Identifying early signs is critical to initiate neuroprotective treatments as early as possible. While pain is prevalent and highly disabling in early PD, no data are currently available on pain perception in iRBD patients, whose condition is of the main risk factor for PD development.",[81,82],"REM Sleep Behavior Disorder (iRBD)","Narcolepsy Type 1",[84,85,86,87,88,89],"parkinson","REM sleep","pain","REM sleep behavior disorder","narcolepsy Type 1","sleep","2026-04-27",{"date":92,"type":93},"2026-05-01","ACTUAL",{"date":95,"type":93},"2026-02-24",{"date":97,"type":75},"2026-08",{"name":5,"class":6},1]