[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609684":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":57,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":24,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":24,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8,14],{"label":9,"type":6,"description":10,"interventionNames":11},"JIA","Inclusion:\n\n1. Age between 9-17\n2. Males and females\n3. English speakers\n4. Able to complete surveys and understand study instructions\n5. Diagnosed or suspected of juvenile arthritis\n\nExclusion Criteria\n\nParticipants will not be enrolled if any of the following criteria exist and based on the investigator discretion:\n\n1. Pregnancy or breastfeeding\n2. (Control Group) Diagnosed with a chronic pain condition\n3. (Control Group) Diagnosed with psychiatric condition including ADHD, anxiety, depression, etc.",[12,13],"Behavioral: Pressure pain thresholds (measured in kilopascal)","Behavioral: Cold pain tolerance (duration in seconds)",{"label":15,"type":6,"description":16,"interventionNames":17},"Controls","Inclusion:\n\n1. Age between 9-17\n2. Males and females\n3. English speakers\n4. Able to complete surveys and understand study instructions\n5. Healthy\n\nExclusion Criteria\n\nParticipants will not be enrolled if any of the following criteria exist and based on the investigator discretion:\n\n1. Pregnancy or breastfeeding\n2. (Control Group) Diagnosed with a chronic pain condition\n3. (Control Group) Diagnosed with psychiatric condition including ADHD, anxiety, depression, etc.",[12,13],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Pressure pain thresholds (measured in kilopascal)","Pressure will be increased continually and participants will be instructed to press a button the first moment they feel pain from the pressure stimulus. The first threshold measurement will be used as a familiarization. The average threshold is calculated from three measurements. Higher value indicates lower experimental pain sensitivity",[15,9],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Cold pain tolerance (duration in seconds)","Cold pain tolerance will be assessed by having participants immerse their hand or foot in a cold (4-12°C) water bath. Tolerance will be defined by the time of hand withdrawal. Pain ratings of cold pain intensity might be obtained periodically, and both pain intensity and pain unpleasantness will be recorded upon hand\u002Ffoot withdrawal. Higher value indicates lower experimental pain sensitivity",[15,9],[30],{"name":31,"affiliation":5,"role":32},"Hadas Nahman-Averbuch, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Alana McMichael, MA","CONTACT","314-273-6194","painlab@wustl.edu",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","St Louis","Missouri","63017","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-90.19789,38.62727,{"lat":51,"lon":50},[54,55,56],{"name":31,"role":36,"phone":37,"phoneExt":24,"email":38},{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},{"name":31,"role":32,"phone":24,"phoneExt":24,"email":24},{"type":32,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Hadas Nahman-Averbuch","Assistant Professor","100609684","pain-in-juvenile-arthritis-100609684",false,"NCT07217782","Pain in Juvenile Arthritis","Pain Processing Mechanisms in Patients With Juvenile Arthritis","Inclusion Criteria:\n\n1. Age between 9-17\n2. Males and females\n3. English speakers\n4. Able to complete surveys and understand study instructions\n5. Juvenile arthritis group: diagnosed or suspected of juvenile arthritis\n6. Control group: healthy\n\nExclusion Criteria:\n\n1. Pregnancy or breastfeeding\n2. (Control Group) Diagnosed with a chronic pain condition\n3. (Control Group) Diagnosed with psychiatric condition including ADHD, anxiety, depression, etc.",true,"ALL","9 Years","17 Years",{"count":72,"type":73},140,"ESTIMATED","INTERVENTIONAL",[76],"NA","Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness. Additional symptoms can include malaise, fatigue, and pain. However, the exact mechanisms contributing to pain are not yet fully understood. Participants will complete a 2.5-hours study session.\n\nIn the study session, psychophysical assessments of thermal and pressure stimuli will be performed. In addition, demographic, social, pubertal maturation, and behavioral and psychological factors will be collected via questionnaires. A saliva sample and\u002For blood draw may occur for the analysis of various immune factors and sex hormones. If a joint aspiration is done as part of their standard of care, we will request a sample of the synovial fluid for analyses of immune, hormonal and\u002For genetic factors. Participants will have the option to participate in additional optional follow-up study visits (every 3 months, up to 1 year) and to complete monthly surveys asking about their juvenile arthritis.",[79],"Juvenile Idiopathic Arthritis","2025-10-14",{"date":82,"type":83},"2025-10-16","ACTUAL",{"date":85,"type":83},"2025-09-15",{"date":87,"type":73},"2035-09",{"name":5,"class":6},1]