[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556551":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":71,"collaborators":10,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":10,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":10,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Cleveland Dental Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"symptomatic acute pulpitis",null,"Patients with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB)",[13,14],"Diagnostic Test: Brain wave analysis using electroencephalography (EEG).","Diagnostic Test: Numerical rate Scale (NRS)",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","Brain wave analysis using electroencephalography (EEG).","Asessment of pain with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG).",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Numerical rate Scale (NRS)","Asessment of pain with the subjective numercal rate scale method (NRS",[9],[26],{"name":27,"affiliation":28,"role":29},"Ahmed A hashem, PhD","CDI Centro Diagnostico Italiano S.p.A","STUDY_DIRECTOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Ahmed I Basyoni","CONTACT","3612290038","a.basyoni@cdiohio.org",{"name":37,"role":33,"phone":38,"phoneExt":10,"email":39},"Abdelrahman Zaghloul","9016324289","a.zaghloul@cdiohio.org",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Cleveland","Ohio","44128","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-81.69541,41.4995,{"lat":52,"lon":51},[55,59,63,66,68],{"name":56,"role":33,"phone":57,"phoneExt":10,"email":58},"Ahmed A Hashem, Profesor","440-502-1591","a.hashem@cdiohio.org",{"name":60,"role":33,"phone":61,"phoneExt":10,"email":62},"Waleed Elmallah, PhD","2163336695","w.elmallah@cdiohio.org",{"name":64,"role":65,"phone":10,"phoneExt":10,"email":10},"Ahmed Basyoni, resident","SUB_INVESTIGATOR",{"name":67,"role":65,"phone":10,"phoneExt":10,"email":10},"Abdelrahman Zaghloul, resident",{"name":69,"role":70,"phone":10,"phoneExt":10,"email":10},"Ahmed Hashem, Prof.","PRINCIPAL_INVESTIGATOR",{"type":72,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100556551","pain-measured-by-nrs-and-eeg-in-acute-pulpitis-100556551",false,"NCT06526572","Pain Measured by NRS and EEG in Acute Pulpitis","Measuring Pain Perception in Patients With Symptomatic Acute Pulpitis and Resistant to Inferior Alveolar Nerve Block Using NRS and Brain Waves","Inclusion Criteria:\n\nAdults aged \\[18-50 years\\]. Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings.\n\nDemonstrates resistance to inferior alveolar nerve block (IANB). Willing and able to provide informed consent to participate in the study. Able to communicate effectively in the language used for study procedures.\n\nExclusion Criteria:\n\nIndividuals with known neurological or psychiatric disorders affecting pain perception.\n\nPregnant individuals or those breastfeeding at the time of the study. History of severe allergies or adverse reactions to local anesthetics or EEG gel.\n\nPresence of significant medical conditions that may contraindicate dental procedures or EEG recordings.\n\nIndividuals taking medications that could significantly affect pain perception (e.g., strong analgesics, sedatives).\n\nAny contraindications for dental procedures or EEG recordings as determined by the study's dental and medical professionals.\n\nInability to understand and follow study instructions.",true,"ALL","18 Years","50 Years",{"count":85,"type":86},50,"ESTIMATED","OBSERVATIONAL","The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB).\n\nThe study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG).\n\nBy integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population.\n\nUltimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.",[90],"Acute Pulpitis",[92,93,94,95],"Acute pulpits","Electroencephalography","Numerical rate scale","Inferior Alveolar Nerve Block","2024-07-29",{"date":98,"type":99},"2024-07-31","ACTUAL",{"date":101,"type":99},"2023-07-01",{"date":103,"type":86},"2025-01-31",{"name":5,"class":6},1]