[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545979":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":32,"centralContacts":36,"locations":41,"responsibleParty":226,"collaborators":10,"id":228,"slug":229,"hasResults":230,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":234,"eligibilityCriteria":235,"healthyVolunteers":236,"sex":237,"minAge":238,"maxAge":10,"enrollmentInfo":239,"targetDuration":10,"studyType":242,"phases":10,"briefSummary":243,"conditions":244,"keywords":258,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":273},{"fullName":5,"class":6},"City of Hope Medical Center","OTHER",[8,14,18,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Pancreatic Cancer Ductal Adenocarcinoma (Training)",null,"Individuals diagnosed with pancreatic ductal adenocarcinoma",[13],"Diagnostic Test: PANcreatic cancer Exosome Early detectiON (PANXEON)",{"label":15,"type":10,"description":16,"interventionNames":17},"Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Training)","Individuals without pancreatic ductal adenocarcinoma",[13],{"label":19,"type":10,"description":11,"interventionNames":20},"Patients with Pancreatic Cancer Ductal Adenocarcinoma (Validation)",[13],{"label":22,"type":10,"description":16,"interventionNames":23},"Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Validation)",[13],[25],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DIAGNOSTIC_TEST","PANcreatic cancer Exosome Early detectiON (PANXEON)","This test will utilize quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) to quantify the expression levels of 5 cell-free and 8 exosome-miRNAs in plasma samples obtained from patients with pancreatic ductal adenocarcinoma and from individuals without it",[15,22,9,19],[31],"PANXEON (PANcreatic cancer Exosome Early detectiON)",[33],{"name":34,"affiliation":5,"role":35},"Ajay Goel, PhD","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":10,"email":40},"CONTACT","6262183452","AJGOEL@COH.ORG",[42,66,80,102,116,131,146,163,180,195,212],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Translational Genomics Research Institute","RECRUITING","Phoenix","Arizona","85004","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-112.07404,33.44838,{"lat":54,"lon":53},[57,60,61,64],{"name":58,"role":38,"phone":10,"phoneExt":10,"email":59},"Daniel Von Hoff","dvh@tgen.org",{"name":58,"role":35,"phone":10,"phoneExt":10,"email":10},{"name":62,"role":63,"phone":10,"phoneExt":10,"email":10},"Haiyong Han","SUB_INVESTIGATOR",{"name":65,"role":63,"phone":10,"phoneExt":10,"email":10},"Derek Cridebring",{"facility":67,"status":44,"city":68,"state":46,"zip":69,"country":48,"countryCode":49,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Honorhealth","Scottsdale","85258",{"type":51,"coordinates":71},[72,73],-111.89903,33.50921,{"lat":73,"lon":72},[76,79],{"name":77,"role":38,"phone":10,"phoneExt":10,"email":78},"Erkut Borazanci","erkut.borazanci@honorhealth.com",{"name":77,"role":63,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":44,"city":81,"state":82,"zip":83,"country":48,"countryCode":49,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Monrovia","California","91016",{"type":51,"coordinates":85},[86,87],-117.99895,34.14806,{"lat":87,"lon":86},[90,92,94,96,98,100],{"name":34,"role":38,"phone":91,"phoneExt":10,"email":40},"626-218-3452",{"name":93,"role":35,"phone":10,"phoneExt":10,"email":10},"Ajay Goel",{"name":95,"role":63,"phone":10,"phoneExt":10,"email":10},"Stanley Hamilton",{"name":97,"role":63,"phone":10,"phoneExt":10,"email":10},"Vincent Chung",{"name":99,"role":63,"phone":10,"phoneExt":10,"email":10},"Caiming Xu",{"name":101,"role":63,"phone":10,"phoneExt":10,"email":10},"Alessandro Mannucci",{"facility":103,"status":44,"city":104,"state":82,"zip":105,"country":48,"countryCode":49,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Hoag Center","Newport Beach","92663",{"type":51,"coordinates":107},[108,109],-117.92895,33.61891,{"lat":109,"lon":108},[112,115],{"name":113,"role":38,"phone":10,"phoneExt":10,"email":114},"Michael Demeure","michael.demeure@hoag.org",{"name":113,"role":63,"phone":10,"phoneExt":10,"email":10},{"facility":117,"status":44,"city":118,"state":119,"zip":120,"country":48,"countryCode":49,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"OSF HealthCare","Peoria","Illinois","61637",{"type":51,"coordinates":122},[123,124],-89.58899,40.69365,{"lat":124,"lon":123},[127,130],{"name":128,"role":38,"phone":10,"phoneExt":10,"email":129},"Chandler Wilfong","chandler.d.wilfong@osfhealthcare.org",{"name":128,"role":63,"phone":10,"phoneExt":10,"email":10},{"facility":132,"status":44,"city":133,"state":134,"zip":135,"country":48,"countryCode":49,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Ochsner Medical Center","Jefferson","Louisiana","70121",{"type":51,"coordinates":137},[138,139],-90.15313,29.96604,{"lat":139,"lon":138},[142,145],{"name":143,"role":38,"phone":10,"phoneExt":10,"email":144},"John Bolton","jbolton@ochsner.org",{"name":143,"role":63,"phone":10,"phoneExt":10,"email":10},{"facility":147,"status":44,"city":148,"state":149,"zip":150,"country":48,"countryCode":49,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Atlantic Health System","Morristown","New Jersey","07960",{"type":51,"coordinates":152},[153,154],-74.48154,40.79677,{"lat":154,"lon":153},[157,160,161],{"name":158,"role":38,"phone":10,"phoneExt":10,"email":159},"Angela Alistar","angela.alistar@atlantichealth.org",{"name":158,"role":63,"phone":10,"phoneExt":10,"email":10},{"name":162,"role":63,"phone":10,"phoneExt":10,"email":10},"Eric Whitman",{"facility":164,"status":44,"city":165,"state":166,"zip":167,"country":48,"countryCode":49,"cosmosGeoPoint":168,"geoPoint":172,"contacts":173},"Piedmont Medical Center","Rock Hill","South Carolina","29732",{"type":51,"coordinates":169},[170,171],-81.02508,34.92487,{"lat":171,"lon":170},[174,177,178],{"name":175,"role":38,"phone":10,"phoneExt":10,"email":176},"Andrew Page","Andrew.Page@piedmont.org",{"name":175,"role":63,"phone":10,"phoneExt":10,"email":10},{"name":179,"role":63,"phone":10,"phoneExt":10,"email":10},"Eyal Meiri",{"facility":181,"status":44,"city":182,"state":183,"zip":184,"country":48,"countryCode":49,"cosmosGeoPoint":185,"geoPoint":189,"contacts":190},"Medical College of Wisconsin","Milwaukee","Wisconsin","53226",{"type":51,"coordinates":186},[187,188],-87.90647,43.0389,{"lat":188,"lon":187},[191,194],{"name":192,"role":38,"phone":10,"phoneExt":10,"email":193},"Douglas Evans","devans@mcw.edu",{"name":192,"role":63,"phone":10,"phoneExt":10,"email":10},{"facility":196,"status":44,"city":197,"state":10,"zip":10,"country":198,"countryCode":199,"cosmosGeoPoint":200,"geoPoint":204,"contacts":205},"Nagoya University","Nagoya","Japan","JP",{"type":51,"coordinates":201},[202,203],136.90641,35.18147,{"lat":203,"lon":202},[206,209,210],{"name":207,"role":38,"phone":10,"phoneExt":10,"email":208},"Yasuhiro Kodera","ykodera@med.nagoya-u.ac.jp",{"name":207,"role":63,"phone":10,"phoneExt":10,"email":10},{"name":211,"role":63,"phone":10,"phoneExt":10,"email":10},"Masamichi Hayashi",{"facility":213,"status":44,"city":214,"state":10,"zip":10,"country":215,"countryCode":10,"cosmosGeoPoint":216,"geoPoint":220,"contacts":221},"Asan Medical Center","Seoul","South Korea",{"type":51,"coordinates":217},[218,219],126.9784,37.566,{"lat":219,"lon":218},[222,225],{"name":223,"role":38,"phone":10,"phoneExt":10,"email":224},"Song Cheol Kim","drksc@amc.seoul.kr",{"name":223,"role":63,"phone":10,"phoneExt":10,"email":10},{"type":227,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100545979","pancreatic-cancer-detection-consortium-100545979",false,"NCT06388967","Pancreatic Cancer Detection Consortium","Early Detection of Pancreatic Cancer: Prospective Study","PCDC","Inclusion Criteria:\n\n* Histological diagnosis of pancreatic ductal adenocarcinoma, stages I-IV (TNM classification, 8th edition)\n* Received standard diagnostic and staging procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.\n* Imaging- or endoscopy-based proof of lack of pancreatic ductal adenocarcinoma at the time of sampling (Non-disease controls)\n\nExclusion Criteria:\n\n* Lack of written informed consent.",true,"ALL","18 Years",{"count":240,"type":241},2000,"ESTIMATED","OBSERVATIONAL","This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.",[245,246,247,248,249,250,251,252,253,254,255,256,257],"Pancreatic Cancer","Pancreatic Carcinoma","Pancreatic Adenocarcinoma","Pancreatic Ductal Adenocarcinoma","Pancreatic Neoplasms","Pancreatic Cancer Stage I","Pancreatic Cancer Stage","Pancreatic Cancer Resectable","Pancreatic Cancer Stage 0","Pancreatic Cancer Stage II","Pancreatic Cancer Stage III","Pancreatic Cancer, Adult","Pancreatic Cancer Non-resectable",[259,260,261,262,263],"Micro RNA","Exosome","Cell free","Early detection","Screening","2025-12-17",{"date":266,"type":267},"2025-12-19","ACTUAL",{"date":269,"type":267},"2023-03-15",{"date":271,"type":241},"2026-06-18",{"name":5,"class":6},11]