[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536935":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":30,"responsibleParty":171,"collaborators":173,"id":177,"slug":178,"hasResults":179,"nctId":180,"briefTitle":181,"officialTitle":181,"acronym":10,"eligibilityCriteria":182,"healthyVolunteers":179,"sex":183,"minAge":184,"maxAge":10,"enrollmentInfo":185,"targetDuration":10,"studyType":188,"phases":10,"briefSummary":189,"conditions":190,"keywords":10,"overallStatus":47,"whyStopped":10,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":201},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational",null,"Participants undergo blood sample collection, complete questionnaires, have their medical records reviewed and undergo pancreatic cyst fluid collection during standard of care endoscopic ultrasounds fine needle aspiration.",[13],"Other: Non-Interventional Study",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Non-Interventional Study","Non-interventional study",[9],[20],{"name":21,"affiliation":22,"role":23},"Ann L. Oberg, PhD","Mayo Clinic in Rochester","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Clinical Trials Referral Office","CONTACT","855-776-0015","mayocliniccancerstudies@mayo.edu",[31,45,63,79,95,111,124,140,156],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":10},"HonorHealth Research Institute","WITHDRAWN","Scottsdale","Arizona","85258","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-111.89903,33.50921,{"lat":43,"lon":42},{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":37,"countryCode":38,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"Piedmont Healthcare","RECRUITING","Atlanta","Georgia","30309",{"type":40,"coordinates":52},[53,54],-84.38798,33.749,{"lat":54,"lon":53},[57,61],{"name":58,"role":27,"phone":59,"phoneExt":10,"email":60},"Meiri Eyal","404-425-1777","eyal.meiri@piedmont.org",{"name":62,"role":23,"phone":10,"phoneExt":10,"email":10},"Meiri Eyal, MD",{"facility":64,"status":47,"city":65,"state":66,"zip":67,"country":37,"countryCode":38,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"OSF Saint Francis Medical Center","Peoria","Illinois","61615",{"type":40,"coordinates":69},[70,71],-89.58899,40.69365,{"lat":71,"lon":70},[74,78],{"name":75,"role":27,"phone":76,"phoneExt":10,"email":77},"Chandler Wilfong, MD","309-691-4005","chandler.d.wilfong@osfhealthcare.org",{"name":75,"role":23,"phone":10,"phoneExt":10,"email":10},{"facility":80,"status":47,"city":81,"state":82,"zip":83,"country":37,"countryCode":38,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"The Johns Hopkins University School of Medicine","Baltimore","Maryland","21231",{"type":40,"coordinates":85},[86,87],-76.61219,39.29038,{"lat":87,"lon":86},[90,94],{"name":91,"role":27,"phone":92,"phoneExt":10,"email":93},"Michael Goggins, 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PhD","503-494-6885","searsr@ohsu.edu",{"name":152,"role":23,"phone":10,"phoneExt":10,"email":10},{"facility":157,"status":47,"city":158,"state":159,"zip":160,"country":37,"countryCode":38,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"University of Pittsburgh","Pittsburgh","Pennsylvania","15232",{"type":40,"coordinates":162},[163,164],-79.99589,40.44062,{"lat":164,"lon":163},[167,170],{"name":168,"role":27,"phone":169,"phoneExt":10,"email":10},"Randall Brand, MD","412-864-7516",{"name":168,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":172,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[174],{"name":175,"class":176},"National Cancer Institute (NCI)","NIH","100536935","pancreatic-cancer-detection-consortium-pcdc-prospective-cohorts-100536935",false,"NCT06271291","Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts","Inclusion Criteria:\n\n* PDAC FAMILY HISTORY OR PDAC RELATED GENETIC MUTATIONS:\n\n  * Age: 50 or older, plus at least one of the following:\n\n    * Mutation unknown or absent:\n\n      * 2+ relatives with PDAC on same side of family where 2 affected are first degree related to each other and at least 1 affected is first degree related to subject;\n      * OR 2+ affected first degree relatives \\[(FDR), defined as blood related parents, siblings, or children\\]\n    * Known pathogenic\u002Flikely pathogenic (P\u002FLP) mutation in at least one of the following:\n\n      * CDKN2A\u002Fp16, Peutz-Jeghers syndrome (PJS) serine\u002Fthreonine kinase 11 (STK11), Hereditary pancreatitis with confirmed protease serine 1 (PRSS1)\n    * OR 1+ or second degree relative (SDR) with PDAC and a known P\u002FLP mutation in one or more of:\n\n      * ATM, BRCA1, BRCA2, PALB2, Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM), TP53\n* HIGH-RISK OR WORRISOME PANCREATIC CYSTS:\n\n  * 18 years of age or greater and meeting Fukuoka worrisome (FW) or Fukuoka high-risk (FHR) criteria\n\n    * High risk stigmata:\n\n      * Obstructive Jaundice in a patient with cystic lesion of the head of the pancreas\n      * Enhancing mural nodule ≥ 5 mm\n      * Main pancreatic duct ≥ 10 mm\n    * Worrisome features:\n\n      * Presence of pancreatic duct stricture, defined as focal pancreatic duct narrowing with upstream duct =\\> 6 mm\n      * Cyst ≥ 3 cm\n      * Enhancing mural nodule \\\u003C 5 mm\n      * Thickened\u002FEnhancing cyst wall\n      * Main duct size 5-9 mm\n      * Pancreatitis\n      * Lymphadenopathy\n      * Increased CA 19-9\n      * Cyst growth rate ≥ 5 mm \u002F2 years\n\nExclusion Criteria:\n\n* Is unable to provide informed consent\n* Has received a non-autologous bone marrow transplant or has an active hematologic malignancy (i.e., leukemia or lymphoma)\n* Current or prior history of PDAC or total pancreatectomy\n* Is currently a prison inmate\n* Is not able to speak or read English","ALL","18 Years",{"count":186,"type":187},30000,"ESTIMATED","OBSERVATIONAL","This study evaluates individuals without pancreatic cancer, but who have been determined to be at higher-than-average lifetime risk of developing pancreatic cancer to help detect pancreatic cancer or other cancers at an earlier time when they might be more easily treated and cured.",[191],"Pancreatic Carcinoma","2026-05-29",{"date":194,"type":195},"2026-06-01","ACTUAL",{"date":197,"type":195},"2024-12-12",{"date":199,"type":187},"2029-11-01",{"name":5,"class":6},9]