[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521153":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":24,"locations":32,"responsibleParty":99,"collaborators":19,"id":102,"slug":103,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":104,"sex":110,"minAge":111,"maxAge":19,"enrollmentInfo":112,"targetDuration":19,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":19,"overallStatus":77,"whyStopped":19,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"Uppsala University Hospital","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Resection of Paraartic lymph nodes","Single arm",[12],"Procedure: PALN resection",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","PALN resection","Resection of paraaortic lymph nodes in pancreatic cancer",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Britt-Marie Karlson","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Christopher Månsson","CONTACT","0186110000","Christopher.mansson@akademiska.se",{"name":22,"role":27,"phone":28,"phoneExt":19,"email":31},"britt-marie.karlson@akademiska.se",[33,48,59,67,75,87],{"facility":34,"status":35,"city":36,"state":19,"zip":19,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Odense University Hospital","NOT_YET_RECRUITING","Odense","Denmark","DK",{"type":40,"coordinates":41},"Point",[42,43],10.38831,55.39594,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":19,"phoneExt":19,"email":19},"Michael Bau Mortensen",{"facility":49,"status":50,"city":51,"state":19,"zip":19,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":58,"contacts":19},"Sahlgrenska university hospital","ACTIVE_NOT_RECRUITING","Gothenburg","Sweden","SE",{"type":40,"coordinates":55},[56,57],11.96679,57.70716,{"lat":57,"lon":56},{"facility":60,"status":50,"city":61,"state":19,"zip":19,"country":52,"countryCode":53,"cosmosGeoPoint":62,"geoPoint":66,"contacts":19},"Linköping University Hospital","Linköping",{"type":40,"coordinates":63},[64,65],15.62157,58.41086,{"lat":65,"lon":64},{"facility":68,"status":50,"city":69,"state":19,"zip":19,"country":52,"countryCode":53,"cosmosGeoPoint":70,"geoPoint":74,"contacts":19},"Skåne University Hospital","Lund",{"type":40,"coordinates":71},[72,73],13.19321,55.70584,{"lat":73,"lon":72},{"facility":76,"status":77,"city":78,"state":19,"zip":19,"country":52,"countryCode":53,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Norrland University Hospital","RECRUITING","Umeå",{"type":40,"coordinates":80},[81,82],20.25972,63.82842,{"lat":82,"lon":81},[85],{"name":86,"role":27,"phone":19,"phoneExt":19,"email":19},"Oskar Franklin",{"facility":5,"status":77,"city":88,"state":19,"zip":89,"country":52,"countryCode":53,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Uppsala","75653",{"type":40,"coordinates":91},[92,93],17.63889,59.85882,{"lat":93,"lon":92},[96],{"name":97,"role":27,"phone":28,"phoneExt":19,"email":98},"Jon Unosson","jon.unosson@uu.se",{"type":100,"investigatorFullName":97,"investigatorTitle":101,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Principal Investigator","100521153","para-aortic-lymph-node-metastasis-in-resectable-pancreatic-cancer-100521153",false,"NCT06065891","Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer","Prevalence and Consequences of Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer: a Prospective Population Based Multicenter Study. The PALN Study","PALN","Inclusion Criteria:\n\nResectable suspected periampullary cancer (requiring duodenopancreatectomy) (NCCN guidelines 2020)\n\nBorderline resectable periampullary cancer (requiring duodenopancreatectomy) (NCCN guidelines 2020)\n\nAge \\>18 years\n\nWritten patient consent\n\nExclusion Criteria:\n\nContraindication for a radical resection procedure\n\nUnresectable tumor (NCCN guidelines 2020) or metastatic disease (lgll station 16 not included)\n\nMental or organic disorders which could interfere with giving informed consent or receiving treatments","ALL","18 Years",{"count":113,"type":114},300,"ESTIMATED","INTERVENTIONAL",[117],"NA","Lymph node metastases are a strong prognostic predictor for pancreatic cancer. Para-aortic lymph nodes (PALN) are the final nodes for periampullary cancers before the cancer cells enter the systemic lymphatic circulation. Some consider these nodes to be regional lymph nodes and dissect them as a part of a routine lymphadenectomy for pancreatic cancer. Others argue that metastases to these nodes represent systemic disease and recommend that radical surgery including extended lymphadenectomy should be abandoned.\n\nThe aim of this study is to define the incidence and clinical consequences of PALN metastasis in patients submitted to a tentative curative resection for carcinoma of the head of the pancreas by systematically resecting paraaortic lymph nodes.\n\nPrimary outcome\n\n1\\) To determine incidence of PALN metastasis in patients submitted to a tentative curative resection\n\nSecondary outcomes\n\n1. To determine prognosis of patients with PALN metastasis after a curative resection\n2. To determine incidence of metastasis in reginal lymph nodes in patients submitted to a tentative curative resection.\n3. To determine prognosis of patients with metastasis in regional lymph nodes in patients submitted to a tentative curative resection.\n4. To address the question of how to optimize the frozen section analyses of PALN as related to the final pathology report.\n\n300 patients are planned to be included in the trial.",[120,121,122],"Pancreas Cancer","Pancreas Adenocarcinoma","Lymph Node Metastasis","2023-09-26",{"date":125,"type":126},"2023-10-04","ACTUAL",{"date":128,"type":126},"2023-09-05",{"date":130,"type":114},"2028-09-05",{"name":97,"class":6},6]