[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603990":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","SHAM_COMPARATOR","patients in control will be weaning using standard criteria",[13],"Device: Sham parasternal intercostal thickening",{"label":15,"type":16,"description":17,"interventionNames":18},"Ultrasound","ACTIVE_COMPARATOR","patient in this group will be weaned using standard criteria plus mean parasternal thickening fraction less than 6.5 %",[19],"Device: Parasternal intercostal thickening fraction",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Parasternal intercostal thickening fraction","Parasternal intercostal thickening fraction less than 6.5%",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham parasternal intercostal thickening","Ultrasound assessment only for purpose of blinding",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Cairo university","CONTACT","+201275716942","kasralainirec@gmail.com",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":26,"geoPoint":26,"contacts":45},"RECRUITING","Cairo","Giza Governorate","6890","Egypt","EG",[46],{"name":47,"role":34,"phone":48,"phoneExt":26,"email":49},"Mina Helmy","01275716942","dr_mina20002010@yahoo.com",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Mina Adolf Helmy","Lecturer of anesthesia and critical care","100603990","parasternal-intercostal-muscle-thickening-as-an-additive-weaning-criterion-100603990",false,"NCT07143695","Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion","Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion to Minimize Re-intubation Rate: a Randomized Controlled Trial","Inclusion Criteria:\n\n* critically ill patient mechanically ventilated for 24 hours or more first spontaneous breathing trial\n\nExclusion Criteria:\n\n* patient refusal difficult ultrasound views tracheostomized patient neuromuscular disorders","ALL","18 Years","65 Years",{"count":65,"type":66},200,"ESTIMATED","INTERVENTIONAL",[69],"NA","Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.",[72],"Critically Ill",[74,75,76],"Weaning","re-intubation","mechanical ventilation","2025-09-01",{"date":79,"type":80},"2025-09-08","ACTUAL",{"date":77,"type":80},{"date":83,"type":66},"2026-08-31",{"name":5,"class":6},1]