[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603380":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":31,"locations":40,"responsibleParty":53,"collaborators":11,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"idiopathic scoliosis (IS)","ACTIVE_COMPARATOR",null,[13],"Procedure: Additional 5 minutes of lying down position during MRI",{"label":15,"type":10,"description":11,"interventionNames":16},"neuromuscular scoliosis (NMS)",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","Additional 5 minutes of lying down position during MRI","During axial MRI for scoliosis assessment, additional 5 minutes of lying down position in order to performing a specific sequence for the study of the vertebral muscles (Diffusion Tensor Imaging).",[9,15],[24,28],{"name":25,"affiliation":26,"role":27},"Hélène Gouz, MD","CHU Raymond Poincaré - APHP","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":26,"role":30},"Robert Carlier, MD, PhD","STUDY_DIRECTOR",[32,36],{"name":25,"role":33,"phone":34,"phoneExt":11,"email":35},"CONTACT","+33149094674","helene.gouze@aphp.fr",{"name":37,"role":33,"phone":38,"phoneExt":11,"email":39},"Marie-Line PISSONNIER, MD, PhD","+33 671612829","ml.pissonnier@gmail.com",[41],{"facility":26,"status":42,"city":43,"state":11,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":11},"RECRUITING","Garches","92380","France","FR",{"type":48,"coordinates":49},"Point",[50,51],2.18232,48.84226,{"lat":51,"lon":50},{"type":54,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100603380","paravertebral-muscles-assessment-using-high-resolution-mri-in-idiopathic-or-neuromuscular-scoliosis-children-100603380",false,"NCT07135765","Paravertebral Muscles Assessment Using High-resolution MRI in Idiopathic or Neuromuscular Scoliosis Children","Paravertebral Muscles Assessment Using High-resolution MRI in Children Suffering From Idiopathic or Neuromuscular Scoliosis","MRISCOL","Inclusion Criteria:\n\n* Children and adolescents aged 10 to 17 years old,\n* Scoliosis (idiopathic or neuromuscular) that is not collapsing\n* Cobb angle \\\u003C40°\n* Female preferred\n* Patient able to walk\n* Average or low BMI \\\u003C20kg\u002Fm2\n* Signature of informed consent by legal guardians\n* Affiliation with a social security scheme (beneficiary or dependent).\n\nExclusion Criteria:\n\n* Refusal of the patient and\u002For parents to participate in the study\n* Inability to cooperate\n* Subject with a contraindication to MRI\n* History of spinal surgery\n* Not affiliated with a social security scheme (beneficiary or entitled person)","ALL","10 Years","17 Years",{"count":67,"type":68},10,"ESTIMATED","INTERVENTIONAL",[71],"NA","Scoliosis is a common three-dimensional spinal deformity defined by vertebral rotation.\n\nApart from collapse scoliosis, clinical and radiological similarities have been observed in children with secondary scoliosis of neuromuscular origin and children with idiopathic scoliosis in terms of the location and type of curvature.\n\nIt seems relevant to study the axial musculature in these children in more detail, particularly the deep muscles (transversospinales muscles) that have a stabilising and rotational function (multifidi and rotatores).\n\nMRI is a non-invasive, non-irradiating technique used in the aetiological diagnosis of idiopathic scoliosis before adolescence and in the diagnosis of secondary scoliosis. However, the muscles are not specifically studied during these examinations. They are performed to analyse the spinal cord and rule out hinge deformities, although this technique does provide information on the paravertebral muscles.\n\nThe muscles of interest should be analysed using the usual sequences, with the addition of a sequence (DTI) specific to the study of deep muscles in children undergoing axial MRI. This adds 5 minutes to the standard MRI procedure.\n\nSeveral morphological muscle parameters would be thus obtained on specific interest areas and then compared between right and left side and between two groups of children, 5 suffering from idiopathic scoliosis and 5 with neuromuscular scoliosis.\n\nIdiopathic scoliosis corresponds to a heterogeneous group of patients in terms of the location, number and progression of the curves. The research hypothesis is that there may be a subgroup of patients with idiopathic scoliosis whose progression and\u002For aetiology is muscular in origin.\n\nMRI could then become a routine examination in the assessment of all scoliosis, whether idiopathic or not.",[74,75,76],"Scoliosis","Scoliosis Idiopathic","Scoliosis Neuromuscular",[78,79,75,76,80,81],"scoliosis","MRI","spine","Children","2025-08-20",{"date":84,"type":85},"2025-08-22","ACTUAL",{"date":87,"type":85},"2025-07-17",{"date":89,"type":68},"2027-08",{"name":5,"class":6},1]