[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100267383":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":28,"responsibleParty":55,"collaborators":57,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":10,"enrollmentInfo":72,"targetDuration":75,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University College, London","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Index case",null,"Patients with a family history of Parkinson's\u002Fparkinsonism, and\u002For early onset Parkinson's\u002Fparkinsonism. The first individual member from a family who is recruited to the study.",{"label":13,"type":10,"description":14,"interventionNames":10},"Affected relatives","Patients with Parkinson's\u002Fparkinsonism who are first or second degree relatives of an Index Case.",{"label":16,"type":10,"description":17,"interventionNames":10},"Unaffected relatives","Participants who do not have Parkinson's\u002Fparkinsonism and are first or second degree relatives of an Index Case.",[19],{"name":20,"affiliation":5,"role":21},"Huw Morris, PhD, FRCP","PRINCIPAL_INVESTIGATOR",[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Study Coordinator","CONTACT","02080168174","ion.pdresearch@ucl.ac.uk",[29,46],{"facility":30,"status":31,"city":32,"state":10,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Royal Free London NHS Foundation Trust","RECRUITING","London","NW3 2PF","United Kingdom","UK",{"type":37,"coordinates":38},"Point",[39,40],-0.12574,51.50853,{"lat":40,"lon":39},[43,45],{"name":24,"role":25,"phone":44,"phoneExt":10,"email":27},"020 8016 8174",{"name":20,"role":21,"phone":10,"phoneExt":10,"email":10},{"facility":47,"status":31,"city":32,"state":10,"zip":48,"country":34,"countryCode":35,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"University College London Hospitals NHS Foundation Trust","WC1N 3BG",{"type":37,"coordinates":50},[39,40],{"lat":40,"lon":39},[53,54],{"name":24,"role":25,"phone":44,"phoneExt":10,"email":27},{"name":20,"role":21,"phone":10,"phoneExt":10,"email":10},{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[58,60],{"name":59,"class":6},"Parkinson's UK",{"name":61,"class":6},"Royal Free Hospital NHS Foundation Trust","100267383","parkinsons-families-project-100267383",false,"NCT02760108","Parkinson's Families Project","PFP","Inclusion Criteria:\n\nClinical diagnosis of Parkinson's disease or parkinsonism, and either family history of Parkinson's\u002Fparkinsonism (first or second degree family member affected by Parkinson's or parkinsonism) AND\u002FOR Early onset Parkinson's\u002Fparkinsonism (symptom onset before the age of 45 years) First or second degree family member of an Index Case, affected or unaffected by Parkinson's\u002Fparkinsonism.\n\nAged over 16 years\n\nExclusion Criteria:\n\nLack of capacity to consent to participate in the project.",true,"ALL","16 Years",{"count":73,"type":74},2000,"ESTIMATED","1 Month","OBSERVATIONAL","One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism. There is a pressing need to study the genetic makeup of family members both with and without Parkinson's. As families share a common genetic background, it is easier to find new Parkinson's genes by studying the genetic makeup of people with Parkinson's alongside other members of their families. We are particularly interested in studying the genetic makeup of two groups of people:\n\n1. those who developed Parkinson's before the age of 45; and\n2. those who have a family history of other relatives affected by Parkinson's.\n\nBy identifying genetic factors that cause Parkinson's, we hope to understand more about the condition. Doing so will lead to the development of better diagnosis, improved disease models, and we hope in time, to the development of better treatment.",[79,80],"Parkinson's Disease","Parkinsonism",[82,83,84,85],"Early onset Parkinson's disease","Familial Parkinson's disease","Parkinson's disease","Genetics","2019-06-10",{"date":88,"type":89},"2019-06-12","ACTUAL",{"date":91,"type":10},"2015-04",{"date":93,"type":74},"2027-01",{"name":5,"class":6},2]