[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544528":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":10,"responsibleParty":30,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":10,"eligibilityCriteria":37,"healthyVolunteers":34,"sex":38,"minAge":10,"maxAge":10,"enrollmentInfo":39,"targetDuration":10,"studyType":42,"phases":10,"briefSummary":43,"conditions":44,"keywords":10,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":10},{"fullName":5,"class":6},"Clinical Hospital Center Rijeka","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"surgical procedure",null,"HS patients, divided into three groups depending on the stage of hidradenitis, would participate in the study.\n\nThe first and second groups would include stage 2-3 patients (according to the Hurley scale) in whom partial or complete clinical remission occurred after biological therapy and surgical treatment was performed according to the guidelines.\n\nIn the third (control) group, we would classify the samples obtained from the above-mentioned patients, from whom we would take a sample of \"normal\" skin measuring 1 x 1 cm.\n\nGOAL: To determine the pathohistological changes in skin and subcutaneous tissues of patients with HS Hurley stage I and II and healthy patients (control group) and compare them with each other.",[13],"Procedure: excision",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","excision","excision of the affected area",[9],[21],{"name":22,"affiliation":23,"role":24},"Damir Juranić, MD","surgeon at CHC Rijeka","PRINCIPAL_INVESTIGATOR",[26],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","+385915132034","damirjuranic@yahoo.com",{"type":31,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100544528","pathophysiological-basis-of-hidradenitis-suppurativa-100544528",false,"NCT06370052","Pathophysiological Basis of Hidradenitis Suppurativa","Inclusion Criteria:\n\n* Hidradenitis Suppurativa\n\nExclusion Criteria:\n\n* patients with no HS\n* patients who do not want to be in the clinical trial","ALL",{"count":40,"type":41},50,"ESTIMATED","OBSERVATIONAL","HS is a chronic inflammatory disease manifested by recurrent inflammatory nodules, abscesses and tunnels under the skin. This disease is characterized by an inflammatory process that takes place in hair follicles, sebaceous glands and surrounding tissue. Because of its frequent recurrence and chronicity, it represents a major public health problem and there is a need for better diagnosis and new and more effective drugs. This research can be a part of realizing the stated needs.",[45],"Hidradenitis Suppurativa","NOT_YET_RECRUITING","2025-02-14",{"date":49,"type":50},"2025-02-18","ACTUAL",{"date":52,"type":41},"2025-02",{"date":54,"type":41},"2026-12-31",{"name":5,"class":6}]