[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100288561":3},{"organization":4,"armGroups":7,"interventions":45,"overallOfficials":76,"centralContacts":80,"locations":90,"responsibleParty":112,"collaborators":51,"id":115,"slug":116,"hasResults":117,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":123,"sex":124,"minAge":125,"maxAge":51,"enrollmentInfo":126,"targetDuration":51,"studyType":129,"phases":130,"briefSummary":132,"conditions":133,"keywords":51,"overallStatus":93,"whyStopped":51,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":144},{"fullName":5,"class":6},"University of Michigan","OTHER",[8,16,24,29,33,37,41],{"label":9,"type":10,"description":11,"interventionNames":12},"Active TES","EXPERIMENTAL","Participants will receive \"real\" tES (tDCS, tACS, tRNS) in which they receive up to 4 milliamps (mA) of stimulation per electrode for up to 40 minutes for up to 260 sessions. As this may be a cross-over design, some participants may receive active and sham conditions.",[13,14,15],"Device: Active tDCS","Device: Active tACS","Device: Active tRNS",{"label":17,"type":18,"description":19,"interventionNames":20},"Sham TES","PLACEBO_COMPARATOR","Participants undergoing this condition will have the exact same procedures as the active group, with the exception that they will receive only sham stimulation for up to 260 sessions.",[21,22,23],"Device: Sham tDCS","Device: Sham tACS","Device: Sham tRNS",{"label":25,"type":10,"description":26,"interventionNames":27},"Cognitively based intervention","Participants may receive a cognitively based intervention that targets the particular cognitive and\u002For functional abilities of interest. This includes methods of cognitive training, cognitive remediation, and cognitive rehabilitation.",[28],"Behavioral: Cognitively based intervention",{"label":30,"type":10,"description":31,"interventionNames":32},"Active TES + Cognitively based intervention","This condition combines active TES and cognitively based interventions for some or all of the study sessions",[13,28,14,15],{"label":34,"type":10,"description":35,"interventionNames":36},"Sham TES + Cognitively based intervention","This condition combines sham TES and cognitively based interventions for some or all of the study sessions",[21,28,22,23],{"label":38,"type":10,"description":39,"interventionNames":40},"Active TES, Sham TES, Cognitively based interventions","This condition combines active and sham TES with cognitively based interventions using a cross-over design",[13,21,28,14,22,15,23],{"label":42,"type":10,"description":43,"interventionNames":44},"Active and Sham TES","Participants will receive active and sham TES",[13,21,14,22,15,23],[46,52,56,60,64,68,72],{"type":47,"name":48,"description":49,"armGroupLabels":50,"otherNames":51},"DEVICE","Active tDCS","Participants will receive active tDCS at up to 4mA per electrode for up to 40 minutes for up to 260 sessions.",[9,30,38,42],null,{"type":47,"name":53,"description":54,"armGroupLabels":55,"otherNames":51},"Sham tDCS","Participants will receive sham tDCS for up to 260 sessions",[38,42,17,34],{"type":57,"name":25,"description":58,"armGroupLabels":59,"otherNames":51},"BEHAVIORAL","Participants may receive a cognitively based intervention that targets the particular cognitive and\u002For functional abilities of interest. This includes methods of cognitive training, cognitive remediation, and cognitive rehabilitation for up to 260 sessions",[30,38,25,34],{"type":47,"name":61,"description":62,"armGroupLabels":63,"otherNames":51},"Active tACS","Participants will receive active transcranial alternating current stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions",[9,30,38,42],{"type":47,"name":65,"description":66,"armGroupLabels":67,"otherNames":51},"Sham tACS","Participants will receive sham transcranial alternating current stimulation for up to 260 sessions",[38,42,17,34],{"type":47,"name":69,"description":70,"armGroupLabels":71,"otherNames":51},"Active tRNS","Participants will receive active transcranial random noise stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions",[9,30,38,42],{"type":47,"name":73,"description":74,"armGroupLabels":75,"otherNames":51},"Sham tRNS","Participants will receive sham transcranial random noise stimulation for up to 260 sessions",[38,42,17,34],[77],{"name":78,"affiliation":5,"role":79},"Benjamin M Hampstead, Ph.D.","PRINCIPAL_INVESTIGATOR",[81,86],{"name":82,"role":83,"phone":84,"phoneExt":51,"email":85},"Kayla Rinna, M.S.","CONTACT","734-936-7739","krinna@med.umich.edu",{"name":87,"role":83,"phone":88,"phoneExt":51,"email":89},"Eileen Robinson, RN, MPH","734-763-1356","robinsoe@med.umich.edu",[91],{"facility":92,"status":93,"city":94,"state":95,"zip":96,"country":97,"countryCode":98,"cosmosGeoPoint":99,"geoPoint":104,"contacts":105},"University of Michigan - Department of Psychiatry","RECRUITING","Ann Arbor","Michigan","48109","United States","US",{"type":100,"coordinates":101},"Point",[102,103],-83.74088,42.27756,{"lat":103,"lon":102},[106,110,111],{"name":107,"role":83,"phone":108,"phoneExt":51,"email":109},"Victor DiRita, B.S.","734-936-0985","victordi@med.umich.edu",{"name":82,"role":83,"phone":84,"phoneExt":51,"email":85},{"name":78,"role":79,"phone":51,"phoneExt":51,"email":51},{"type":79,"investigatorFullName":113,"investigatorTitle":114,"investigatorAffiliation":5,"oldNameTitle":51,"oldOrganization":51},"Benjamin Hampstead, PhD","Investigator","100288561","patient-centered-neurorehabilitation-pcn-100288561",false,"NCT03036319","Patient-Centered NeuroRehabilitation (PCN)","Patient-Centered NeuroRehabilitation","PCN","Inclusion Criteria:\n\n1. Individuals who have reported cognitive dysfunction and cognitively intact participants.\n2. Participants will be age 50 or older\n\nExclusion Criteria:\n\n1. A history of epilepsy\n2. Sensory or motor impairments that limit the ability to take part in the study\n3. Current alcohol or drug abuse\u002Fdependence\n4. Those who are currently pregnant or may become pregnant during the duration of the study (if there is a question of pregnancy, pregnancy tests will be available for participants at no charge)\n\nThose who are being evaluated for TES methodology will also be excluded for 1) metallic or electronic implant 2) skull plates or other cranial implants that affect TES",true,"ALL","50 Years",{"count":127,"type":128},500,"ESTIMATED","INTERVENTIONAL",[131],"NA","As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as \"normal\" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve tasks people have trouble doing in everyday life. Transcranial electrical stimulation uses small amounts of electricity to try to alter brain functioning. These approaches may help improve cognitive abilities like attention, learning, memory, finding words, and problem solving as well as everyday functioning. The goal of this study is to identify how to best use these methods, either alone or in combination.",[134],"Cognitive Deficit","2026-01-12",{"date":137,"type":138},"2026-01-14","ACTUAL",{"date":140,"type":51},"2016-06",{"date":142,"type":128},"2027-11",{"name":5,"class":6},1]