[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607472":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":26,"enrollmentInfo":63,"targetDuration":26,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":78,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Korea University Anam Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RH group","EXPERIMENTAL","Participants receive an app-based, patient-centered prehabilitation program from randomization until surgery (no extra clinic visits). The program includes weekly home six-minute walk tests (6MWT) logged in the app, brief daily check-ins (exercise performed, simple nutrition targets, mood\u002Fstress), push reminders, and short educational video\u002Fhandout content. Safety prompts and validity checks (continuous 6 minutes, pause limits, outlier flags) are embedded in the app.\n\nAll on-site assessments are aligned with routine care: preoperative-day in-hospital testing (primary 6MWD, plus grip\u002FTUG\u002FHADS; InBody via fee-free pathway where available) and one routine postoperative outpatient visit (3 or 6 months; site-standard) for follow-up secondary measures. Usual perioperative care is provided per site ERAS practice.",[13],"Behavioral: App-based prehabilitation program",{"label":15,"type":16,"description":17,"interventionNames":18},"UC group","ACTIVE_COMPARATOR","Participants receive standard perioperative care per each site's ERAS-consistent routine (preoperative counseling\u002Feducation, routine mobilization). No study app is provided and no remote 6MWT logging is required. For outcomes collection only, participants undergo the same preoperative-day in-hospital assessment (primary 6MWD, plus grip\u002FTUG\u002FHADS; InBody via fee-free pathway where available) and one routine postoperative outpatient visit (3 or 6 months; site-standard). No additional study-specific clinic visits are required.",[19],"Other: Usual care (ERAS-standard perioperative care)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","App-based prehabilitation program","A lightweight mobile\u002Fweb application delivering a patient-centered prehabilitation program from randomization until surgery. Features include: weekly home six-minute walk tests (6MWT) logged in the app; brief daily check-ins for exercise performed, simple nutrition targets, and mood\u002Fstress; push reminders; short educational video\u002Fhandout content; and CSV export for analysis. The app provides standardized instructions and safety prompts for the home 6MWT and basic validity checks (continuous 6 minutes, pause limits, outlier flags). No additional study-specific clinic visits are required beyond routine preoperative admission and one routine postoperative outpatient visit.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Usual care (ERAS-standard perioperative care)","Standard perioperative counseling\u002Feducation and routine mobilization per institutional ERAS practice. No study app is provided and no remote 6MWT logging is required. Outcome assessments are collected at routine preoperative admission (including in-hospital 6MWT per protocol) and at one routine postoperative outpatient visit (≈3 or 6 months per unified site policy). No additional study-specific clinic visits are required.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Eunji Ko, M.D., Ph.D.","CONTACT","+82-10-3423-8249","froken.ko@gmail.com",[38],{"facility":5,"status":26,"city":39,"state":26,"zip":26,"country":40,"countryCode":26,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Seoul","South Korea",{"type":42,"coordinates":43},"Point",[44,45],126.9784,37.566,{"lat":45,"lon":44},[48],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Eunji Ko","Clinical Assistant Professor","100607472","patient-centered-rehabilitation-program-to-advance-recovery-100607472",false,"NCT07189000","Patient-centered REhabilitation Program to Advance REcovery","A Patient-centered Prehabilitation Program to Enhance Postoperative Recovery in Patients With Malignant Cancer","PREPARE-CAN","Inclusion Criteria:\n\n* Adults ≥18 years.\n* Elective cancer surgery planned under general anesthesia at a participating site (e.g., gastrointestinal, hepatobiliary-pancreatic, thoracic, gynecologic, or other site-approved cancer operations).\n* Ambulatory: able to walk independently (assistive device such as a cane is allowed) and deemed safe to perform a six-minute walk test (6MWT) per investigator judgment.\n* Smartphone access and app use: owns\u002Fhas regular access to a smartphone capable of running the study app and agrees to use the app (notifications, weekly home 6MWT logging, brief daily check-ins).\n* Preoperative lead-in: expected interval of ≈14 days or more between consent\u002Frandomization and surgery to allow prehabilitation exposure (shorter intervals may be screened but must allow minimum onboarding and at least one home 6MWT).\n* Able to understand study procedures and provide written informed consent (Korean or English literacy sufficient to follow app instructions).\n\nExclusion Criteria:\n\n* Emergency surgery or surgery date that cannot accommodate even minimal prehabilitation onboarding.\n* ASA IV or higher, or any unstable\u002Fcritical condition that, in the investigator's opinion, makes participation unsafe.\n* Contraindications to 6MWT\u002Flight walking, including but not limited to: unstable angina, recent myocardial infarction (≤30 days), decompensated heart failure, uncontrolled clinically significant arrhythmia, severe symptomatic aortic stenosis, severe uncontrolled pulmonary disease, or investigator-judged safety concerns (e.g., resting severe hypoxemia, high fall risk).\n* Non-ambulatory status or musculoskeletal\u002Fneurologic conditions that preclude performing a 6MWT.\n* Cognitive impairment or psychiatric\u002Fbehavioral conditions that preclude informed consent or reliable app use.\n* Inability or unwillingness to install\u002Fuse the study app (or lack of regular smartphone access).\n* Concurrent enrollment in another interventional clinical trial that would confound outcomes or burden participants (per investigator judgment).\n* Any other medical or logistical condition that, in the opinion of the investigator, would interfere with protocol adherence, outcome assessment on the preoperative day, or the routine postoperative follow-up visit.","ALL","19 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"NA","The goal of this clinical trial is to learn whether an app-based, patient-centered prehabilitation program improves preoperative functional capacity in adults scheduled for elective cancer surgery. The main questions it aims to answer are:\n\nDoes the program increase the six-minute walk distance (6MWD) measured on the preoperative day (within 24-48 hours before surgery)?\n\nCompared with usual care, does the program improve preoperative adherence to home 6MWT practice and patient-reported anxiety\u002Fdepression (HADS)?\n\nResearchers will compare an app-based prehabilitation program to usual care to see if the program improves preoperative functional capacity.\n\nParticipants will:\n\nUse a study app to perform weekly home six-minute walk tests (6MWT) and complete brief daily check-ins (exercise, nutrition, psychological status) before surgery.\n\nAttend routine preoperative admission (no extra visit) for in-hospital 6MWT (primary endpoint) and brief assessments (grip strength, Timed Up \\& Go, HADS, skeletal muscle mass by InBody where available\u002Ffee-free).\n\nAttend one routine postoperative outpatient visit at 3 or 6 months (site-standard timing) for follow-up assessments.\n\nNo additional study-specific clinic visits are required outside usual care.",[71,72,73],"Cancer","Frailty","Prehabilitation",[75,76,77],"prehabilitation","frailty","cancer","NOT_YET_RECRUITING","2025-09-16",{"date":81,"type":82},"2025-09-23","ACTUAL",{"date":84,"type":65},"2026-01-01",{"date":86,"type":65},"2027-12-31",{"name":5,"class":6},1]