[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638322":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":41,"responsibleParty":60,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":25,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Reverse Trendelenburg Position","EXPERIMENTAL","Participants undergo ureteroscopic lithotripsy in reverse Trendelenburg positioning with attempted in situ treatment of the proximal ureteral stone to minimize proximal migration.",[13],"Procedure: Reverse Trendelenburg Position",{"label":15,"type":16,"description":17,"interventionNames":18},"T-Tilt Position","ACTIVE_COMPARATOR","Participants undergo intentional relocation of the proximal ureteral stone into the kidney followed by intrarenal lithotripsy performed in the T-tilt position.",[19],"Procedure: T-Tilt Position",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Patients will be positioned in reverse Trendelenburg at a 20 degree incline with the use of a digital protractor. Lithotripsy will be performed within the ureter with attempts to prevent proximal migration and until all fragments are removed.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Stone will be intentionally relocated into the kidney when feasible, followed by intrarenal lithotripsy in T-tilt position. In the T-tilt position the table is angled 15-degree Trendelenburg and 15-degree airplane away from the surgical side kidney with the use of a digital protractor. This allows fragments to rest in a superior and medial position away from the lower pole to facilitate removal.",[15],[30],{"name":31,"affiliation":5,"role":32},"Mantu Gupta, MD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","212-241-1272","mantu.gupta@mountsinai.org",{"name":39,"role":35,"phone":36,"phoneExt":25,"email":40},"Blair Gallante, MPH","blair.gallante@mountsinai.org",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Mount Sinai West","RECRUITING","New York","10019","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-74.00597,40.71427,{"lat":53,"lon":52},[56,58,59],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":57},"Mantu.gupta@mountsinai.org",{"name":39,"role":35,"phone":36,"phoneExt":25,"email":40},{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"type":32,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Mantu Gupta","Professor of Urology","100638322","patient-positioning-for-treatment-of-proximal-ureteral-stones-100638322",false,"NCT07601932","Patient Positioning for Treatment of Proximal Ureteral Stones","Optimal Patient Positioning and Strategy for the Treatment of Proximal Ureteral Stones","Inclusion criteria:\n\n* Adults aged 18 years and older.\n* Diagnosed with kidney stones and scheduled for fURS.\n* Stone burden \\> 1 cm and\u002For multiple stones will be eligible.\n* Able and willing to provide informed consent.\n\nExclusion criteria:\n\n* Pregnant persons as determined by pre-operative urine pregnancy test (standard of care at the institution)\n* Untreated UTI\n* Patients with urinary anomalies (e.g., urinary diversion, ureteral reconstruction, horseshoe kidney)\n* Single stone \\\u003C 1 cm","ALL","18 Years",{"count":73,"type":74},54,"ESTIMATED","INTERVENTIONAL",[77],"NA","Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment. Reverse Trendelenburg positioning has been shown to reduce proximal stone migration and operative time in ureteral stones, while the T-tilt position improves intrarenal stone clearance. The optimal strategy for proximal ureteral stones (treating stones in situ using reverse Trendelenburg versus pushing stones into the kidney followed by intrarenal treatment in T-tilt) remains unknown.\n\nThis randomized controlled trial compares these two strategies, with primary focus on operative time as a measure of procedural efficiency.\n\nA total of 54 patients (27 per arm) will be enrolled at Mount Sinai West.",[80],"Ureteral Stone","2026-06-02",{"date":83,"type":84},"2026-06-04","ACTUAL",{"date":86,"type":84},"2026-05-21",{"date":88,"type":74},"2027-12",{"name":5,"class":6},1]