[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471350":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":32,"locations":41,"responsibleParty":60,"collaborators":64,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":10,"enrollmentInfo":86,"targetDuration":89,"studyType":90,"phases":10,"briefSummary":91,"conditions":92,"keywords":99,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Dr. Negrin University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ozone group",null,"Patients treated with ozone as adjuvant palliative therapy. The procedure of ozone administration, dosage, frequency, and duration of ozone treatment will depend on the treated symptom and clinical evolution. Usually planned 40 sessions.",[13],"Other: Ozone therapy",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Ozone therapy","Systemic and\u002For local ozone administration. Dosage, frequency, and duration of ozone treatment will depend on the treated symptom and clinical evolution. Usually planned 40 sessions.",[9],[20,24,28,30],{"name":21,"affiliation":22,"role":23},"Bernardino Clavo, MD, PhyD","Dr. Negrín University Hospital, Las Palmas, Spain","STUDY_CHAIR",{"name":25,"affiliation":26,"role":27},"Pedro G Serrano-Aguilar, MD, PhyD","Servicio de Evaluación. Servicio Canario de Salud. Spain","STUDY_DIRECTOR",{"name":21,"affiliation":22,"role":29},"PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":22,"role":29},"Miguel A Caramés-Álvarez, MD",[33,37],{"name":21,"role":34,"phone":35,"phoneExt":10,"email":36},"CONTACT","(34)928449278","bernardinoclavo@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":10,"email":40},"Francisco Rodríguez-Esparragón, BSci, PhyD","(34)928449288","afrodesp@gmail.com",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Dr. Negrín University Hospital","RECRUITING","Las Palmas","35019","Spain","ES",{"type":50,"coordinates":51},"Point",[52,53],-16.16555,28.58232,{"lat":53,"lon":52},[56,57,59],{"name":21,"role":34,"phone":35,"phoneExt":10,"email":36},{"name":58,"role":34,"phone":39,"phoneExt":10,"email":40},"Francisco Rodríguez-Esparragón, BSc, PhyD",{"name":31,"role":29,"phone":10,"phoneExt":10,"email":10},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Bernardino Clavo, MD, PhD","MD, PhD, Head of Research Unit",[65,68,70,72,74],{"name":66,"class":67},"Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC)","UNKNOWN",{"name":69,"class":6},"Servicio Canario de Salud",{"name":71,"class":6},"Council of Gran Canaria",{"name":73,"class":6},"Red de Investigación en Servicios de Salud en Enfermedades Crónicas",{"name":75,"class":67},"Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna","100471350","patients-referred-to-the-chronic-pain-unit-for-palliative-treatment-with-ozone-therapy-between-2022-and-2025-100471350",false,"NCT05417737","Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025","Prospective and Observational Study of Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025. (EPOOzo)","EPOOzo","Inclusion Criteria:\n\n1. Adults \\> = 18 years old.\n2. Patients submitted to the Chronic Pain Unit of the Hospital Universitario de Gran Canaria Dr. Negrín for symptomatic\u002Fpalliative treatment with ozone therapy because conventional treatment does not exist, it has been unsuccessful, or it is associated with high risk or high morbidity.\n3. After evaluation of symptoms and patients, it exists a potential benefit of adding ozone treatment to the current treatment.\n4. Patients have no contraindications for ozone treatment.\n5. Patients have signed and dated the informed consent for the compassionated ozone treatment and the specific informed consent for this study\n\nExclusion Criteria:\n\n1. Age \\\u003C 18 years old.\n2. Psychiatric illness or social situations that would limit compliance with study requirements.\n3. Those who are incapable to fill in the scales used to measure variables.\n4. Hemodynamically or clinically unstable patients or uncontrolled severe illness.\n5. Uncontrolled cancer disease requiring chemotherapy treatment.\n6. Life expectancy \\\u003C 6 months\n7. Contraindication or disability or to attend scheduled treatments.\n8. Known allergy to ozone.\n9. Pregnancy at the time of enrollment (for systemic ozone therapy). 10 Hemochromatosis (for systemic ozone therapy).\n\n11\\. Known significant glucose-6-phosphate dehydrogenase deficiency (favism, acute hemolytic anemia) (for systemic ozone therapy).\n\n12\\. Patients who do not meet all the inclusion criteria","ALL","18 Years",{"count":87,"type":88},105,"ESTIMATED","28 Weeks","OBSERVATIONAL","The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms, who have been referred to the HUGCDN Chronic Pain Unit for adjuvant palliative treatment with ozone therapy between June-2022 and December-2025",[93,94,95,96,97,98],"Radiation Toxicity","Chemotherapeutic Toxicity","Chemotherapy-induced Peripheral Neuropathy","Delayed Wound Healing","Chronic Pain","Refractory Pain",[95,100,101,102,103,104,105,16,106],"Radiation-induced toxicity","Cancer-treatment side effects","Delayed wound healing","Chronic pain","Health-related quality of life","Anxiety and Depression","Refractory pain","2025-08-25",{"date":109,"type":110},"2025-09-02","ACTUAL",{"date":112,"type":110},"2022-06-15",{"date":114,"type":88},"2026-06-30",{"name":62,"class":6},1]