[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582737":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":64,"collaborators":67,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":18,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":18,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":99,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"Georgia State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Peanut","EXPERIMENTAL","43 g of peanut butter (1snack cup) 3 x\u002Fweek, 42 g of dry roasted peanuts (1\u002F3 of a cup) 3x\u002Fweek, or 56 g of peanut flour 1x\u002Fweek for 6 months",[13],"Dietary Supplement: Peanuts",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","No intervention",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIETARY_SUPPLEMENT","Peanuts","43 g of peanut butter (1 snack cup) 3 x\u002Fweek, 42 g of dry roasted peanuts (1\u002F3 of a cup) 3x\u002Fweek, or 56 g of peanut flour 1x\u002Fweek for 6 months.",[9],[26],{"name":27,"affiliation":5,"role":28},"Rafaela G Feresin, PhD","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","404-413-1233","peanuts@gsu.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Atlanta","Georgia","30303","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-84.38798,33.749,{"lat":46,"lon":45},[49,50,51,54,56,58,60,62],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"name":52,"role":53,"phone":18,"phoneExt":18,"email":18},"Tricia Z King, PhD","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":18,"phoneExt":18,"email":18},"Andrew T Gewirtz, PhD",{"name":57,"role":53,"phone":18,"phoneExt":18,"email":18},"Elizabeth L Tighe, PhD",{"name":59,"role":53,"phone":18,"phoneExt":18,"email":18},"Brett J Wong, PhD",{"name":61,"role":53,"phone":18,"phoneExt":18,"email":18},"Vince D Calhoun, PhD",{"name":63,"role":53,"phone":18,"phoneExt":18,"email":18},"Puja K Mehta, PhD",{"type":28,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Rafaela G. Feresin","Associate Professor",[68,71],{"name":69,"class":70},"United States Department of Agriculture (USDA)","FED",{"name":72,"class":6},"The Peanut Institute","100582737","peanuts-for-cardiometabolic-brain-and-intestinal-health-100582737",false,"NCT06867198","Peanuts for Cardiometabolic, Brain, and Intestinal Health","Impact of Peanuts on Cardiometabolic, Cognitive, and Intestinal Health in Prediabetes Among Racially Diverse Populations","Inclusion Criteria:\n\n* men and women\n* 20-59 years of age\n* BMI: 24.5 - 35.5 kg\u002Fm\\^2\n* Prediabetes (fasting blood glucose levels 100-125 mg\u002FdL and\u002For HbA1c between 5.7-6.4%)\n* Ability to give consent\n\nExclusion Criteria:\n\n* Allergies to peanuts and peanut products\n* Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs\n* Active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological diseases or severe head injury\n* Smoking\n* Consumes greater than 2 alcoholic beverages per day\n* Consumes antioxidant, probiotic, and prebiotic supplements\n* Pregnant or Lactating\n* Actively participating in a weight loss program\n\nMRI Exclusion Criteria:\n\n* Certain neurological disorders (e.g., uncontrolled seizure disorders)\n* Braces on their teeth, a cardiac pacemaker; hearing aid; other metal in the body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects","ALL","20 Years","59 Years",{"count":84,"type":85},72,"ESTIMATED","INTERVENTIONAL",[88],"NA","The overall objective of this 14-month randomized crossover study is to seek evidence demonstrating that daily consumption of peanuts and peanut products improve cardiometabolic, cognitive, and intestinal health in a racially diverse prediabetes population.",[91,92,93,94,95,96,97,98],"Prediabetes","Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)","Cognition","Microvascular Function","Gut Microbiota","Endothelial Function (Reactive Hyperemia)","Arterial Stiffness, Blood Pressure","Adult",[100,101,102,103,104,105,106,107,108,109,110,111,112,113,114],"prediabetes","peanuts","functional foods","nuts","metabolic health","insulin resistance","type II diabetes","microvascular function","dietary intervention","cognitive function","vascular function","neuroimaging","endothelial function","cardiovascular health","gut microbiota","2026-03-23",{"date":117,"type":118},"2026-03-27","ACTUAL",{"date":120,"type":118},"2025-03-06",{"date":122,"type":85},"2027-09",{"name":5,"class":6},1]