[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100468168":3},{"organization":4,"armGroups":7,"interventions":50,"overallOfficials":57,"centralContacts":66,"locations":75,"responsibleParty":982,"collaborators":985,"id":992,"slug":56,"hasResults":993,"nctId":994,"briefTitle":995,"officialTitle":995,"acronym":56,"eligibilityCriteria":996,"healthyVolunteers":993,"sex":997,"minAge":998,"maxAge":999,"enrollmentInfo":1000,"targetDuration":56,"studyType":1003,"phases":1004,"briefSummary":1006,"conditions":1007,"keywords":1011,"overallStatus":78,"whyStopped":56,"lastUpdateSubmitDate":1016,"lastUpdatePostDateStruct":1017,"startDateStruct":1020,"completionDateStruct":1022,"leadSponsor":1024,"locationsCount":1025},{"fullName":5,"class":6},"University of Michigan","OTHER",[8,14,18,22,26,30,34,38,42,46],{"label":9,"type":10,"description":11,"interventionNames":12},"Cooling 0 hours","EXPERIMENTAL","Participants will be kept at a normal temperature for the whole 5 days.",[13],"Device: Therapeutic Hypothermia",{"label":15,"type":10,"description":16,"interventionNames":17},"Cooling 12 hours","The participant will be cooled to 33°Celsius (C) for 12 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Cooling 18 hours","The participant will be cooled to 33°C for 18 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Cooling 24 hours","The participant will be cooled to 33°C for 24 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Cooling 36 hours","The participant will be cooled to 33°C for 36 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Cooling 48 hours","The participant will be cooled to 33°C for 48 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":35,"type":10,"description":36,"interventionNames":37},"Cooling 60 hours","The participant will be cooled to 33°C for 60 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":39,"type":10,"description":40,"interventionNames":41},"Cooling 72 hours","The participant will be cooled to 33°C for 72 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":43,"type":10,"description":44,"interventionNames":45},"Cooling 84 hours","The participant will be cooled to 33°C for 84 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],{"label":47,"type":10,"description":48,"interventionNames":49},"Cooling 96 hours","The participant will be cooled to 33°C for 96 hours, slowly rewarmed over approximately 16 hours, and then will be kept at a normal temperature (36.8°C or 98.6°F) until the end of the 5th day.",[13],[51],{"type":52,"name":53,"description":54,"armGroupLabels":55,"otherNames":56},"DEVICE","Therapeutic Hypothermia","Participants will receive therapeutic hypothermia for the assigned number of hours with controlled rewarming,\n\nA zero hour cooling duration (normothermia) treatment arm will be opened for enrollment if there is not an increase in the treatment effect across the durations. Alternatively, longer durations (84 or 96 hours) will be opened for enrollment if the treatment effects are increasing (rather than plateauing or decreasing) through 72 hours.",[9,15,19,23,27,31,35,39,43,47],null,[58,61,64],{"name":59,"affiliation":5,"role":60},"Frank Moler, MD","PRINCIPAL_INVESTIGATOR",{"name":62,"affiliation":63,"role":60},"Alex Topjian, MD","Children's Hospital of Philadelphia",{"name":65,"affiliation":5,"role":60},"William Meurer, MD",[67,71],{"name":59,"role":68,"phone":69,"phoneExt":56,"email":70},"CONTACT","734-764-5302","fmoler@umich.edu",{"name":72,"role":68,"phone":73,"phoneExt":56,"email":74},"Moni Weber","734-232-4803","monij@umich.edu",[76,96,112,122,138,156,167,181,196,211,225,239,255,269,285,301,313,328,344,359,374,386,403,418,433,444,459,475,491,505,521,533,548,562,579,599,613,627,642,662,677,690,704,720,735,749,759,774,784,800,815,835,847,860,875,890,904,921,938,954,968],{"facility":77,"status":78,"city":79,"state":80,"zip":81,"country":82,"countryCode":83,"cosmosGeoPoint":84,"geoPoint":89,"contacts":90},"University of Alabama at Birmingham \u002F Children's of Alabama","RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":85,"coordinates":86},"Point",[87,88],-86.80249,33.52066,{"lat":88,"lon":87},[91,95],{"name":92,"role":68,"phone":93,"phoneExt":56,"email":94},"Michele Kong, MD","205-638-9387","mkong@uabmc.edu",{"name":92,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":97,"status":78,"city":98,"state":99,"zip":100,"country":82,"countryCode":83,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Phoenix Children's Hospital","Phoenix","Arizona","85016",{"type":85,"coordinates":102},[103,104],-112.07404,33.44838,{"lat":104,"lon":103},[107,111],{"name":108,"role":68,"phone":109,"phoneExt":56,"email":110},"F. Anthony Willyerd, MD","602-471-5064","fwillyerd@phoenixchildrens.com",{"name":108,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":113,"status":114,"city":115,"state":99,"zip":116,"country":82,"countryCode":83,"cosmosGeoPoint":117,"geoPoint":121,"contacts":56},"Banner University Medical Center - Tucson","ACTIVE_NOT_RECRUITING","Tucson","85719",{"type":85,"coordinates":118},[119,120],-110.92648,32.22174,{"lat":120,"lon":119},{"facility":123,"status":78,"city":124,"state":125,"zip":126,"country":82,"countryCode":83,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Memorial Health - Miller Children's and Women's Hospital of Long Beach","Long Beach","California","90806-1701",{"type":85,"coordinates":128},[129,130],-118.18923,33.76696,{"lat":130,"lon":129},[133,137],{"name":134,"role":68,"phone":135,"phoneExt":56,"email":136},"Christopher Babbitt, MD","562-933-8743","CBabbitt@memorialcare.org",{"name":134,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":139,"status":78,"city":140,"state":125,"zip":141,"country":82,"countryCode":83,"cosmosGeoPoint":142,"geoPoint":146,"contacts":147},"Children's Hospital of Los Angeles","Los Angeles","90027",{"type":85,"coordinates":143},[144,145],-118.24368,34.05223,{"lat":145,"lon":144},[148,152],{"name":149,"role":68,"phone":150,"phoneExt":56,"email":151},"Bradley De Souza, MD","323-361-8202","bdesouza@chla.usc.edu",{"name":153,"role":68,"phone":154,"phoneExt":56,"email":155},"David Baron, MS","323-361-6329","dbaron@chla.usc.edu",{"facility":157,"status":78,"city":140,"state":125,"zip":158,"country":82,"countryCode":83,"cosmosGeoPoint":159,"geoPoint":161,"contacts":162},"University of California Los Angeles (UCLA) Mattel Children's Hospital","90095",{"type":85,"coordinates":160},[144,145],{"lat":145,"lon":144},[163,166],{"name":164,"role":68,"phone":56,"phoneExt":56,"email":165},"Anil Sapru, MD","asapru@mednet.ucla.edu",{"name":164,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":168,"status":78,"city":169,"state":125,"zip":170,"country":82,"countryCode":83,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"University of California - Oakland \u002F UCSF Benoiff Children's Hospital Oakland","Oakland","94609",{"type":85,"coordinates":172},[173,174],-122.2708,37.80437,{"lat":174,"lon":173},[177,180],{"name":178,"role":68,"phone":179,"phoneExt":56,"email":56},"Natalie Cvijanovich, MD","510-428-3302",{"name":178,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":182,"status":78,"city":183,"state":125,"zip":184,"country":82,"countryCode":83,"cosmosGeoPoint":185,"geoPoint":189,"contacts":190},"Children's Hospital of Orange County","Orange","92868-4203",{"type":85,"coordinates":186},[187,188],-117.85311,33.78779,{"lat":188,"lon":187},[191,195],{"name":192,"role":68,"phone":193,"phoneExt":56,"email":194},"Adam Schwarz, MD","714-509-8620","aschwarz@choc.org",{"name":192,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":197,"status":78,"city":198,"state":125,"zip":199,"country":82,"countryCode":83,"cosmosGeoPoint":200,"geoPoint":204,"contacts":205},"University of California, Davis","Sacramento","95817",{"type":85,"coordinates":201},[202,203],-121.4944,38.58157,{"lat":203,"lon":202},[206,210],{"name":207,"role":68,"phone":208,"phoneExt":56,"email":209},"Heather Siefkes, MD","916-734-7620","hsiefkes@ucdavis.edu",{"name":207,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":212,"status":78,"city":213,"state":125,"zip":214,"country":82,"countryCode":83,"cosmosGeoPoint":215,"geoPoint":219,"contacts":220},"University of California - San Francisco (UCSF) Benioff Children's Hospital San Francisco","San Francisco","94158",{"type":85,"coordinates":216},[217,218],-122.41942,37.77493,{"lat":218,"lon":217},[221,224],{"name":222,"role":68,"phone":56,"phoneExt":56,"email":223},"Patrick McQuillen, MD","patrick.mcquillen@ucsf.edu",{"name":222,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":226,"status":78,"city":227,"state":125,"zip":228,"country":82,"countryCode":83,"cosmosGeoPoint":229,"geoPoint":233,"contacts":234},"Stanford","Santa Clara","95050",{"type":85,"coordinates":230},[231,232],-121.95524,37.35411,{"lat":232,"lon":231},[235,238],{"name":236,"role":68,"phone":56,"phoneExt":56,"email":237},"Tim Cornell, MD","tcornell@stanford.edu",{"name":236,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":240,"status":78,"city":241,"state":242,"zip":243,"country":82,"countryCode":83,"cosmosGeoPoint":244,"geoPoint":248,"contacts":249},"University of Florida (UF) Health Shands Children's Hospital","Gainesville","Florida","32610-0296",{"type":85,"coordinates":245},[246,247],-82.32483,29.65163,{"lat":247,"lon":246},[250,254],{"name":251,"role":68,"phone":252,"phoneExt":56,"email":253},"Shruthi Mahadevaiah, MD","313-318-7383","smahadevaiah@ufl.edu",{"name":251,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":256,"status":78,"city":257,"state":242,"zip":258,"country":82,"countryCode":83,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"University of Miami","Miami","33124",{"type":85,"coordinates":260},[261,262],-80.19366,25.77427,{"lat":262,"lon":261},[265,268],{"name":266,"role":68,"phone":56,"phoneExt":56,"email":267},"Jennifer Munoz Pareja, MD","jcm457@med.miami.edu",{"name":266,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":270,"status":78,"city":271,"state":242,"zip":272,"country":82,"countryCode":83,"cosmosGeoPoint":273,"geoPoint":277,"contacts":278},"Johns Hopkins All Children's Hospital","St. Petersburg","33701",{"type":85,"coordinates":274},[275,276],-82.67927,27.77086,{"lat":276,"lon":275},[279,283],{"name":280,"role":68,"phone":281,"phoneExt":56,"email":282},"Anthony Sochet, MD., M.Sc.","727-767-4343","asochet1@jh.edu",{"name":284,"role":60,"phone":56,"phoneExt":56,"email":56},"Nathan Dean, MD",{"facility":286,"status":78,"city":287,"state":288,"zip":289,"country":82,"countryCode":83,"cosmosGeoPoint":290,"geoPoint":294,"contacts":295},"Ann & Robert Lurie Children's Hospital of Chicago","Chicago","Illinois","60611",{"type":85,"coordinates":291},[292,293],-87.65005,41.85003,{"lat":293,"lon":292},[296,300],{"name":297,"role":68,"phone":298,"phoneExt":56,"email":299},"Craig Smith, MD","312-227-4800","CMSmith@luriechildrens.org",{"name":297,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":302,"status":78,"city":287,"state":288,"zip":303,"country":82,"countryCode":83,"cosmosGeoPoint":304,"geoPoint":306,"contacts":307},"Comer Children's Hospital, University of Chicago","60637",{"type":85,"coordinates":305},[292,293],{"lat":293,"lon":292},[308,312],{"name":309,"role":68,"phone":310,"phoneExt":56,"email":311},"Casey Stulce, MD","773-834-3837","cstulce@bsd.uchicago.edu",{"name":309,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":314,"status":78,"city":315,"state":288,"zip":316,"country":82,"countryCode":83,"cosmosGeoPoint":317,"geoPoint":321,"contacts":322},"Children's Hospital of Illinois","Peoria","61637",{"type":85,"coordinates":318},[319,320],-89.58899,40.69365,{"lat":320,"lon":319},[323,327],{"name":324,"role":68,"phone":325,"phoneExt":56,"email":326},"Sandeep Tripathi, MD","309-624-0719","sandeept@uic.edu",{"name":324,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":329,"status":78,"city":330,"state":331,"zip":332,"country":82,"countryCode":83,"cosmosGeoPoint":333,"geoPoint":337,"contacts":338},"Riley Children's Health","Indianapolis","Indiana","46202",{"type":85,"coordinates":334},[335,336],-86.15804,39.76838,{"lat":336,"lon":335},[339,343],{"name":340,"role":68,"phone":341,"phoneExt":56,"email":342},"Matthew Yuknis, MD","317-944-3345","myuknis@iupui.edu",{"name":340,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":345,"status":78,"city":346,"state":347,"zip":348,"country":82,"countryCode":83,"cosmosGeoPoint":349,"geoPoint":353,"contacts":354},"University of Iowa, Carver College of Medicine","Iowa City","Iowa","52242",{"type":85,"coordinates":350},[351,352],-91.53017,41.66113,{"lat":352,"lon":351},[355,358],{"name":356,"role":68,"phone":56,"phoneExt":56,"email":357},"Kari Wellnitz, MD","kari-wellnitz@uiowa.edu",{"name":356,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":360,"status":78,"city":361,"state":362,"zip":363,"country":82,"countryCode":83,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"University of Maryland Children's Hospital","Baltimore","Maryland","21201",{"type":85,"coordinates":365},[366,367],-76.61219,39.29038,{"lat":367,"lon":366},[370,373],{"name":371,"role":68,"phone":56,"phoneExt":56,"email":372},"Siddhartha Dante, MD","abhutta@som.umaryland.edu",{"name":371,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":375,"status":78,"city":361,"state":362,"zip":376,"country":82,"countryCode":83,"cosmosGeoPoint":377,"geoPoint":379,"contacts":380},"Johns Hopkins Medicine Children's Center","21287",{"type":85,"coordinates":378},[366,367],{"lat":367,"lon":366},[381,385],{"name":382,"role":68,"phone":383,"phoneExt":56,"email":384},"Caitlin O'Brien, MD, MPH","720-635-1730","Cobrie19@jhmi.edu",{"name":382,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":387,"status":78,"city":388,"state":389,"zip":390,"country":82,"countryCode":83,"cosmosGeoPoint":391,"geoPoint":395,"contacts":396},"MassGeneral Hospital for Children","Boston","Massachusetts","02114",{"type":85,"coordinates":392},[393,394],-71.05977,42.35843,{"lat":394,"lon":393},[397,401],{"name":398,"role":68,"phone":399,"phoneExt":56,"email":400},"Sarah MD Murphy, MD","617-724-4380","samurphy@mgh.harvard.edu",{"name":402,"role":60,"phone":56,"phoneExt":56,"email":56},"Sarah Murphy, MD",{"facility":404,"status":78,"city":405,"state":406,"zip":407,"country":82,"countryCode":83,"cosmosGeoPoint":408,"geoPoint":412,"contacts":413},"University of Michigan CS Mott Children's Hospital","Ann Arbor","Michigan","48109",{"type":85,"coordinates":409},[410,411],-83.74088,42.27756,{"lat":411,"lon":410},[414,417],{"name":415,"role":68,"phone":56,"phoneExt":56,"email":416},"Ryan Barbaro, MD","barbaror@umich.edu",{"name":415,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":419,"status":78,"city":420,"state":406,"zip":421,"country":82,"countryCode":83,"cosmosGeoPoint":422,"geoPoint":426,"contacts":427},"Children's Hospital of Michigan","Detroit","48201",{"type":85,"coordinates":423},[424,425],-83.04575,42.33143,{"lat":425,"lon":424},[428,432],{"name":429,"role":68,"phone":430,"phoneExt":56,"email":431},"Kathleen Meert, MD","313-745-5870","meert1kl@cmich.edu",{"name":429,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":434,"status":435,"city":436,"state":437,"zip":438,"country":82,"countryCode":83,"cosmosGeoPoint":439,"geoPoint":443,"contacts":56},"University of Minnesota Fairview Masonic Children's Hospital","WITHDRAWN","Minneapolis","Minnesota","55454",{"type":85,"coordinates":440},[441,442],-93.26384,44.97997,{"lat":442,"lon":441},{"facility":445,"status":78,"city":446,"state":447,"zip":448,"country":82,"countryCode":83,"cosmosGeoPoint":449,"geoPoint":453,"contacts":454},"Washington University \u002F St. Louis Children's Hospital","St Louis","Missouri","63110",{"type":85,"coordinates":450},[451,452],-90.19789,38.62727,{"lat":452,"lon":451},[455,458],{"name":456,"role":68,"phone":56,"phoneExt":56,"email":457},"Stuart Friess, MD","friess@wustl.edu",{"name":456,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":460,"status":78,"city":461,"state":462,"zip":463,"country":82,"countryCode":83,"cosmosGeoPoint":464,"geoPoint":468,"contacts":469},"University of Nebraska Medical Center","Omaha","Nebraska","68114",{"type":85,"coordinates":465},[466,467],-95.94043,41.25626,{"lat":467,"lon":466},[470,474],{"name":471,"role":68,"phone":472,"phoneExt":56,"email":473},"Alyson Baker, MD MS","402-955-7257","alybaker@childrensnebraska.org",{"name":471,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":476,"status":78,"city":477,"state":478,"zip":479,"country":82,"countryCode":83,"cosmosGeoPoint":480,"geoPoint":484,"contacts":485},"Albany Medical Center","Albany","New York","12208",{"type":85,"coordinates":481},[482,483],-73.75623,42.65258,{"lat":483,"lon":482},[486,490],{"name":487,"role":68,"phone":488,"phoneExt":56,"email":489},"Ilana Harwayne-Gidansky, MD","518-262-5127","harwayi@amc.edu",{"name":487,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":492,"status":78,"city":493,"state":478,"zip":494,"country":82,"countryCode":83,"cosmosGeoPoint":495,"geoPoint":499,"contacts":500},"University of Buffalo \u002F Oishei Children's Hospital","Buffalo","14203",{"type":85,"coordinates":496},[497,498],-78.87837,42.88645,{"lat":498,"lon":497},[501,504],{"name":502,"role":68,"phone":56,"phoneExt":56,"email":503},"Ryan Breuer, MD","ryanbrue@buffalo.edu",{"name":502,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":506,"status":78,"city":507,"state":478,"zip":508,"country":82,"countryCode":83,"cosmosGeoPoint":509,"geoPoint":513,"contacts":514},"Cohen Children's Medical Center of NY \u002F Northwell Health","New Hyde Park","11040",{"type":85,"coordinates":510},[511,512],-73.68791,40.7351,{"lat":512,"lon":511},[515,519],{"name":516,"role":68,"phone":517,"phoneExt":56,"email":518},"Taylor Nickerson, MD","718-470-3668","tnickerson@northwell.edu",{"name":520,"role":60,"phone":56,"phoneExt":56,"email":56},"Todd Sweberg, MD",{"facility":522,"status":78,"city":478,"state":478,"zip":523,"country":82,"countryCode":83,"cosmosGeoPoint":524,"geoPoint":528,"contacts":529},"Mount Sinai Icahn \u002F Kravis Children's Hospital","10029",{"type":85,"coordinates":525},[526,527],-74.00597,40.71427,{"lat":527,"lon":526},[530,532],{"name":531,"role":68,"phone":56,"phoneExt":56,"email":56},"Shubhi Kaushik, MD",{"name":531,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":534,"status":78,"city":535,"state":478,"zip":536,"country":82,"countryCode":83,"cosmosGeoPoint":537,"geoPoint":541,"contacts":542},"University of Rochester Medical Center","Rochester","14642-8667",{"type":85,"coordinates":538},[539,540],-77.61556,43.15478,{"lat":540,"lon":539},[543,547],{"name":544,"role":68,"phone":545,"phoneExt":56,"email":546},"Jake Deines, MD","585-273-5269","Jake_deines@urmc.rochester.edu",{"name":544,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":549,"status":78,"city":550,"state":478,"zip":551,"country":82,"countryCode":83,"cosmosGeoPoint":552,"geoPoint":556,"contacts":557},"Montefiore Einstein Hospital Moses Campus","The Bronx","10467",{"type":85,"coordinates":553},[554,555],-73.86641,40.84985,{"lat":555,"lon":554},[558],{"name":559,"role":68,"phone":560,"phoneExt":56,"email":561},"Alvaro J Coronado Munoz, MD","718-741-2432","acoronadom@montefiore.org",{"facility":563,"status":78,"city":564,"state":565,"zip":566,"country":82,"countryCode":83,"cosmosGeoPoint":567,"geoPoint":571,"contacts":572},"The University of North Carolina at Chapel Hill","Chapel Hill","North Carolina","27599-7220",{"type":85,"coordinates":568},[569,570],-79.05584,35.9132,{"lat":570,"lon":569},[573,577],{"name":574,"role":68,"phone":575,"phoneExt":56,"email":576},"Kieran Leong, DO","919-966-7495","Kieran_Leong@med.unc.edu",{"name":578,"role":60,"phone":56,"phoneExt":56,"email":56},"Benny Joyner, MD, MPH",{"facility":580,"status":78,"city":581,"state":582,"zip":583,"country":82,"countryCode":83,"cosmosGeoPoint":584,"geoPoint":588,"contacts":589},"Children's Hospital Medical Center of Akron","Akron","Ohio","44308",{"type":85,"coordinates":585},[586,587],-81.51901,41.08144,{"lat":587,"lon":586},[590,594,597,598],{"name":591,"role":68,"phone":592,"phoneExt":56,"email":593},"Ryan Nofziger, MD","330-543-8639","mofziger@akronchildrens.org",{"name":595,"role":68,"phone":592,"phoneExt":56,"email":596},"Chris Page-Goertz, MD","cpage-goertz@akronchildrens.org",{"name":591,"role":60,"phone":56,"phoneExt":56,"email":56},{"name":595,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":600,"status":78,"city":601,"state":582,"zip":602,"country":82,"countryCode":83,"cosmosGeoPoint":603,"geoPoint":607,"contacts":608},"Cincinnati Children's Hospital","Cincinnati","45229",{"type":85,"coordinates":604},[605,606],-84.51439,39.12711,{"lat":606,"lon":605},[609,612],{"name":610,"role":68,"phone":56,"phoneExt":56,"email":611},"Ranjit Chima, MD","ranjit.chima@cchmc.org",{"name":610,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":614,"status":78,"city":615,"state":582,"zip":616,"country":82,"countryCode":83,"cosmosGeoPoint":617,"geoPoint":621,"contacts":622},"Ohio State University \u002F Nationwide Children's Hospital","Columbus","43205",{"type":85,"coordinates":618},[619,620],-82.99879,39.96118,{"lat":620,"lon":619},[623,626],{"name":624,"role":68,"phone":56,"phoneExt":56,"email":625},"Marlina Lovett, MD","marlina.lovett@nationwidechildrens.org",{"name":624,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":628,"status":78,"city":629,"state":582,"zip":630,"country":82,"countryCode":83,"cosmosGeoPoint":631,"geoPoint":635,"contacts":636},"Dayton Children's Hospital","Dayton","45404",{"type":85,"coordinates":632},[633,634],-84.19161,39.75895,{"lat":634,"lon":633},[637,641],{"name":638,"role":68,"phone":639,"phoneExt":56,"email":640},"Hemanth Lingadevaru, MD","937-641-5168","lingadevaruh@childrensdayton.org",{"name":638,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":643,"status":78,"city":644,"state":645,"zip":646,"country":82,"countryCode":83,"cosmosGeoPoint":647,"geoPoint":651,"contacts":652},"Oregon Health & Science University Doernbecher Children's Hospital","Portland","Oregon","97239",{"type":85,"coordinates":648},[649,650],-122.67621,45.52345,{"lat":650,"lon":649},[653,657,661],{"name":654,"role":68,"phone":655,"phoneExt":56,"email":656},"Mohamud Daya, MD, MS","503-494-7248","dayam@ohsu.edu",{"name":658,"role":68,"phone":659,"phoneExt":56,"email":660},"Serena Kelly, MS","503-789-4580","phromsiv@ohsu.edu",{"name":658,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":663,"status":78,"city":664,"state":665,"zip":666,"country":82,"countryCode":83,"cosmosGeoPoint":667,"geoPoint":671,"contacts":672},"Penn State University \u002F Penn State Children's Hospital","Hershey","Pennsylvania","17033",{"type":85,"coordinates":668},[669,670],-76.65025,40.28592,{"lat":670,"lon":669},[673,676],{"name":674,"role":68,"phone":56,"phoneExt":56,"email":675},"Neal Thomas, MD","nthomas@pennstatehealth.psu.edu",{"name":674,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":63,"status":78,"city":678,"state":665,"zip":679,"country":82,"countryCode":83,"cosmosGeoPoint":680,"geoPoint":684,"contacts":685},"Philadelphia","19104",{"type":85,"coordinates":681},[682,683],-75.16362,39.95238,{"lat":683,"lon":682},[686,689],{"name":687,"role":68,"phone":56,"phoneExt":56,"email":688},"Matthew Kirschen, MD","kirschenm@chop.edu",{"name":687,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":691,"status":78,"city":692,"state":665,"zip":693,"country":82,"countryCode":83,"cosmosGeoPoint":694,"geoPoint":698,"contacts":699},"Children's Hospital of Pittsburgh (UPMC)","Pittsburgh","15224",{"type":85,"coordinates":695},[696,697],-79.99589,40.44062,{"lat":697,"lon":696},[700,703],{"name":701,"role":68,"phone":56,"phoneExt":56,"email":702},"Ericka Fink, MD","finkel@ccm.upmc.edu",{"name":701,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":705,"status":78,"city":706,"state":707,"zip":708,"country":82,"countryCode":83,"cosmosGeoPoint":709,"geoPoint":713,"contacts":714},"University of Tennesses Health Center \u002F Le Bonheur Children's","Memphis","Tennessee","38104",{"type":85,"coordinates":710},[711,712],-90.04898,35.14953,{"lat":712,"lon":711},[715,718],{"name":716,"role":68,"phone":56,"phoneExt":56,"email":717},"Laurel Metzler, MD","lmetzler@uthsc.edu",{"name":719,"role":60,"phone":56,"phoneExt":56,"email":56},"Laruel Metzler, MD",{"facility":721,"status":78,"city":722,"state":723,"zip":724,"country":82,"countryCode":83,"cosmosGeoPoint":725,"geoPoint":729,"contacts":730},"Children's Medical Center of Dallas","Dallas","Texas","75235",{"type":85,"coordinates":726},[727,728],-96.80667,32.78306,{"lat":728,"lon":727},[731,734],{"name":732,"role":68,"phone":56,"phoneExt":56,"email":733},"Joshua Wolovits, MD","joshua.wolovits@utsouthwestern.edu",{"name":732,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":736,"status":78,"city":737,"state":723,"zip":738,"country":82,"countryCode":83,"cosmosGeoPoint":739,"geoPoint":743,"contacts":744},"Children's Memorial Hermann Hospital","Houston","77030",{"type":85,"coordinates":740},[741,742],-95.36327,29.76328,{"lat":742,"lon":741},[745],{"name":746,"role":68,"phone":747,"phoneExt":56,"email":748},"Thao Nguyen, MD","832-512-1595","Thao.L.Nguyen@uth.tmc.edu",{"facility":750,"status":78,"city":737,"state":723,"zip":738,"country":82,"countryCode":83,"cosmosGeoPoint":751,"geoPoint":753,"contacts":754},"Texas Children's Hospital, Baylor",{"type":85,"coordinates":752},[741,742],{"lat":742,"lon":741},[755,758],{"name":756,"role":68,"phone":56,"phoneExt":56,"email":757},"Jennifer Erklauer, MD","jclee@bcm.edu",{"name":756,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":760,"status":78,"city":761,"state":723,"zip":762,"country":82,"countryCode":83,"cosmosGeoPoint":763,"geoPoint":767,"contacts":768},"The University of Texas Health Science Center at San Antonio","San Antonio","78229",{"type":85,"coordinates":764},[765,766],-98.49363,29.42412,{"lat":766,"lon":765},[769,773],{"name":770,"role":68,"phone":771,"phoneExt":56,"email":772},"Theodore Wu, MD","210-567-5816","wut@uthscsa.edu",{"name":770,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":775,"status":435,"city":776,"state":777,"zip":778,"country":82,"countryCode":83,"cosmosGeoPoint":779,"geoPoint":783,"contacts":56},"Primary Children's Hospital, University of Utah School of Medicine","Salt Lake City","Utah","84108",{"type":85,"coordinates":780},[781,782],-111.89105,40.76078,{"lat":782,"lon":781},{"facility":785,"status":78,"city":786,"state":787,"zip":788,"country":82,"countryCode":83,"cosmosGeoPoint":789,"geoPoint":793,"contacts":794},"American Family Children's Hospital","Madison","Wisconsin","53705",{"type":85,"coordinates":790},[791,792],-89.40123,43.07305,{"lat":792,"lon":791},[795,799],{"name":796,"role":68,"phone":797,"phoneExt":56,"email":798},"Peter Ferrazzano, MD","608-265-4839","ferrazzano@pediatrics.wisc.edu",{"name":796,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":801,"status":78,"city":802,"state":787,"zip":803,"country":82,"countryCode":83,"cosmosGeoPoint":804,"geoPoint":808,"contacts":809},"Children's Wisconsin","Milwaukee","53226",{"type":85,"coordinates":805},[806,807],-87.90647,43.0389,{"lat":807,"lon":806},[810,814],{"name":811,"role":68,"phone":812,"phoneExt":56,"email":813},"Binod Balakrishnan, MD","414-266-3360","bbalakris@mcw.edu",{"name":811,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":816,"status":78,"city":817,"state":818,"zip":819,"country":820,"countryCode":821,"cosmosGeoPoint":822,"geoPoint":826,"contacts":827},"Queensland Children's Hospital","Brisbane","Queensland","4101","Australia","AU",{"type":85,"coordinates":823},[824,825],153.02809,-27.46794,{"lat":825,"lon":824},[828,832],{"name":829,"role":68,"phone":830,"phoneExt":56,"email":831},"Adrian Mattke, FRACP","+61 (4) 0169 8994","Adrian.Mattke@health.qld.gov.au",{"name":833,"role":68,"phone":56,"phoneExt":56,"email":834},"Tara Williams, MSN","Tara.Williams@health.qld.gov.au",{"facility":836,"status":78,"city":837,"state":818,"zip":56,"country":820,"countryCode":821,"cosmosGeoPoint":838,"geoPoint":842,"contacts":843},"Townsville University Hospital","Douglas",{"type":85,"coordinates":839},[840,841],146.75234,-19.32394,{"lat":841,"lon":840},[844],{"name":845,"role":68,"phone":56,"phoneExt":56,"email":846},"Andrew Clift, FCICM, FACRRM, GMC","Andrew.Clift@health.qld.gov.au",{"facility":848,"status":78,"city":849,"state":818,"zip":56,"country":820,"countryCode":821,"cosmosGeoPoint":850,"geoPoint":854,"contacts":855},"Gold Coast University Hospital","Southport",{"type":85,"coordinates":851},[852,853],153.39796,-27.96724,{"lat":853,"lon":852},[856,859],{"name":857,"role":68,"phone":830,"phoneExt":56,"email":858},"Shane George, FACEM","shane.george@uq.edu.au",{"name":833,"role":68,"phone":56,"phoneExt":56,"email":834},{"facility":861,"status":78,"city":862,"state":863,"zip":864,"country":820,"countryCode":821,"cosmosGeoPoint":865,"geoPoint":869,"contacts":870},"Women's and Children's Hospital","North Adelaide","South Australia","5006",{"type":85,"coordinates":866},[867,868],138.59141,-34.90733,{"lat":868,"lon":867},[871],{"name":872,"role":68,"phone":873,"phoneExt":56,"email":874},"Subdodh Ganu, MBBS, MD, FCICM","61 8 8161 6881","subodh.ganu@sa.gov.au",{"facility":876,"status":78,"city":877,"state":878,"zip":879,"country":820,"countryCode":821,"cosmosGeoPoint":880,"geoPoint":884,"contacts":885},"Monash Medical Centre","Clayton","Victoria","3168",{"type":85,"coordinates":881},[882,883],145.11667,-37.91667,{"lat":883,"lon":882},[886,889],{"name":887,"role":68,"phone":56,"phoneExt":56,"email":888},"Meredith Allen, MB.BS, FRACP","meredith.allen@monashhealth.org",{"name":887,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":891,"status":78,"city":892,"state":878,"zip":893,"country":820,"countryCode":821,"cosmosGeoPoint":894,"geoPoint":898,"contacts":899},"Royal Children's Hospital","Parkville","3052",{"type":85,"coordinates":895},[896,897],144.95,-37.78333,{"lat":897,"lon":896},[900],{"name":901,"role":68,"phone":902,"phoneExt":56,"email":903},"Warrick Butt, FELSO","61 (4) 0777 6886","Warwick.Butt@rch.org.au",{"facility":905,"status":78,"city":906,"state":907,"zip":56,"country":820,"countryCode":821,"cosmosGeoPoint":908,"geoPoint":912,"contacts":913},"Perth Children's Hospital","Nedlands","Western Australia",{"type":85,"coordinates":909},[910,911],115.8073,-31.98184,{"lat":911,"lon":910},[914,918],{"name":915,"role":68,"phone":916,"phoneExt":56,"email":917},"Simon Erikson, FRACP","61 (8) 6456 4437","simon.erickson@health.wa.gov.au",{"name":919,"role":68,"phone":56,"phoneExt":56,"email":920},"Jenipher Chumbres Flores, MSN","Jenipher.ChumbesFlores@health.wa.gov.au",{"facility":922,"status":78,"city":923,"state":924,"zip":56,"country":925,"countryCode":926,"cosmosGeoPoint":927,"geoPoint":931,"contacts":932},"The Hospital for Sick Children","Toronto","Ontario","Canada","CA",{"type":85,"coordinates":928},[929,930],-79.39864,43.70643,{"lat":930,"lon":929},[933,937],{"name":934,"role":68,"phone":935,"phoneExt":56,"email":936},"Anne-Marie Guerguerian, MD, PhD","416-813-7654","anne-marie.guerguerian@sickkids.ca",{"name":934,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":939,"status":78,"city":940,"state":941,"zip":942,"country":943,"countryCode":944,"cosmosGeoPoint":945,"geoPoint":949,"contacts":950},"Starship Children's Hospital","Grafton","Auckland","1142","New Zealand","NZ",{"type":85,"coordinates":946},[947,948],174.76566,-36.86029,{"lat":948,"lon":947},[951],{"name":952,"role":68,"phone":56,"phoneExt":56,"email":953},"John S Beca, FRACP, FCICM","JohnBeca@adhb.govt.nz",{"facility":955,"status":78,"city":79,"state":56,"zip":56,"country":956,"countryCode":957,"cosmosGeoPoint":958,"geoPoint":962,"contacts":963},"Birmingham Children's Hospital, United Kingdom","United Kingdom","UK",{"type":85,"coordinates":959},[960,961],-1.89983,52.48142,{"lat":961,"lon":960},[964,967],{"name":965,"role":68,"phone":56,"phoneExt":56,"email":966},"Hari Krishnan, MD","hari.krishnan2@nhs.net",{"name":965,"role":60,"phone":56,"phoneExt":56,"email":56},{"facility":969,"status":78,"city":970,"state":56,"zip":971,"country":956,"countryCode":957,"cosmosGeoPoint":972,"geoPoint":976,"contacts":977},"Bristol Royal Hospital for Children","Bristol","BS2 8BJ",{"type":85,"coordinates":973},[974,975],-2.59665,51.45523,{"lat":975,"lon":974},[978],{"name":979,"role":68,"phone":980,"phoneExt":56,"email":981},"Omar Aziz, MSC, MRCGP, MRCPCH, DGM","44 3788956254","Omer.Aziz@uhbw.nhs.uk",{"type":60,"investigatorFullName":983,"investigatorTitle":984,"investigatorAffiliation":5,"oldNameTitle":56,"oldOrganization":56},"Frank W. Moler, M.D, M.S","Professor of Pediatrics",[986,989],{"name":987,"class":988},"National Heart, Lung, and Blood Institute (NHLBI)","NIH",{"name":990,"class":991},"Kennedy Krieger Institute, Baltimore, MD","UNKNOWN","100468168",false,"NCT05376267","Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)","Inclusion criteria:\n\n* Age 2 days to \\\u003C 18 years with corrected gestational age of at least 38 weeks\n* Chest compressions for at least 2 minutes\n* Coma or encephalopathy after resuscitation from Out-of-Hospital Cardiac Arrest (OHCA)\n* Requires continuous mechanical ventilation through endotracheal tube or tracheostomy\n* Definitive temperature control device initiated\n* Randomization within 6 hours of Return of Spontaneous Circulation (ROSC)\n* Informed consent from Legally Authorized Representative (LAR) including intent to maintain life support for 120 hours\n\nExclusion criteria:\n\n* Glasgow Coma Motor Score (GCMS) = 6\n* LAR does not speak English or Spanish\n* Duration of Cardiopulmonary Resuscitation (CPR) \\> 60 minutes\n* Severe hemodynamic instability with continuous infusion of epinephrine or norepinephrine of 2 micrograms per kilogram per minute (μg\u002Fkg\u002Fminute) or initiation of Extracorporeal membrane oxygenation (ECMO)\n* Pre-existing severe neurodevelopmental deficits with Pediatric Cerebral Performance Category (PCPC) =5 or progressive degenerative encephalopathy\n* Pre-existing terminal illness, unlikely to survive to one year\n* Cardiac arrest associated with brain, thoracic, or abdominal trauma\n* Active and refractory severe bleeding prior to randomization\n* Extensive burns or skin lesions incompatible with surface cooling\n* Planned early withdrawal of life support before 120 hours\n* Sickle cell anemia\n* Pre-existing cryoglobulinemia\n* Non-fatal drowning in ice covered water\n* Central nervous system tumor with ongoing chemotherapy\n* Previous enrollment in P-ICECAP trial\n* Prisoner\n* Chronic hypothermia\n* New post-cardiac arrest diabetes insipidus\n* Pregnancy","ALL","2 Days","17 Years",{"count":1001,"type":1002},900,"ESTIMATED","INTERVENTIONAL",[1005],"NA","This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest.\n\nThe study team hypothesizes that longer durations of cooling may improve either the proportion of children that attain a good neurobehavioral recovery or may result in better recovery among the proportion already categorized as having a good outcome.",[1008,1009,1010],"Cardiac Arrest, Out-Of-Hospital","Hypothermia, Induced","Hypoxia-Ischemia, Brain",[1012,1013,1014,1015],"Bayesian Adaptive Clinical Trial","Hypothermia, therapeutic","Coma","Pediatric","2026-06-03",{"date":1018,"type":1019},"2026-06-05","ACTUAL",{"date":1021,"type":1019},"2022-08-05",{"date":1023,"type":1002},"2028-03-31",{"name":5,"class":6},61]