[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634190":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":31,"locations":31,"responsibleParty":40,"collaborators":31,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":31,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":31,"enrollmentInfo":54,"targetDuration":31,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":31,"overallStatus":65,"whyStopped":31,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":31},{"fullName":5,"class":6},"Ankara City Hospital Bilkent","OTHER",[8,16,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Fixed PEEP","ACTIVE_COMPARATOR","Ventilation with constant PEEP of 5 cmH₂O throughout surgery.",[13,14,15],"Procedure: Fixed PEEP Ventilation","Procedure: Decremental PEEP Strategy","Procedure: Incremental PEEP Strategy",{"label":17,"type":18,"description":19,"interventionNames":20},"Decremental PEEP","EXPERIMENTAL","PEEP is gradually decreased to identify the level associated with the lowest driving pressure or lowest mechanical power.",[13,14,15],{"label":22,"type":18,"description":23,"interventionNames":24},"Incremental PEEP","PEEP is gradually increased to determine the optimal level corresponding to the lowest driving pressure or mechanical power.",[13,14,15],[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","Fixed PEEP Ventilation","Patients receive mechanical ventilation with a constant positive end-expiratory pressure (PEEP) of 5 cmH₂O throughout the surgical procedure.",[17,9,22],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Decremental PEEP Strategy","PEEP is gradually decreased from a higher level to determine the optimal PEEP associated with the lowest driving pressure or lowest mechanical power, and this level is maintained during surgery.",[17,9,22],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Incremental PEEP Strategy","PEEP is gradually increased from a lower level to identify the optimal PEEP corresponding to the lowest driving pressure or mechanical power, and this level is maintained during surgery.",[17,9,22],{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Betül Güven","Assos prof","100634190","peep-strategies-and-mechanical-power-in-robotic-surgery-100634190",false,"NCT07536464","PEEP Strategies and Mechanical Power in Robotic Surgery","Comparison of Incremental, Decremental, and Fixed PEEP Strategies on Mechanical Power and Postoperative Oxygenation in Robotic Surgery: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age\\>= 18\n* ASA I-III\n* Elective robotic surgery\n\nExclusion Criteria:\n\n* COPD GOLD ≥2\n\n  * Restrictive lung disease\n  * BMI \\>40 kg\u002Fm²\n  * Heart failure\n  * Preoperative oxygen requirement\n  * Need for postoperative mechanical ventilation\n  * Refusal to participate",true,"ALL","18 Years",{"count":55,"type":56},120,"ESTIMATED","INTERVENTIONAL",[59],"NA","Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.\n\nPositive end-expiratory pressure (PEEP) is a key determinant of lung recruitment; however, fixed PEEP strategies may not be optimal for all patients. Individualized PEEP titration strategies, including incremental and decremental approaches, may better optimize lung mechanics.\n\nThis randomized controlled trial aims to compare the effects of incremental, decremental, and fixed PEEP strategies on cumulative mechanical power (MP-AUC) and postoperative oxygenation in patients undergoing robotic surgery.",[62,63,64],"Postoperative Pulmonary Complications","Impaired Oxygenation","Mechanical Ventilation","NOT_YET_RECRUITING","2026-04-11",{"date":68,"type":69},"2026-04-17","ACTUAL",{"date":71,"type":56},"2026-04-15",{"date":73,"type":56},"2026-06-30",{"name":5,"class":6}]