[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553731":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":92,"collaborators":94,"id":101,"slug":102,"hasResults":103,"nctId":104,"briefTitle":25,"officialTitle":105,"acronym":9,"eligibilityCriteria":106,"healthyVolunteers":103,"sex":107,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":18,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":120,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PEGISUS","EXPERIMENTAL","PEGISUS is based on two existing evidence-based interventions: Reducing Alcohol and Drug use and other Problem behavior in Adolescent Learners (RAD-PAL) and Manhood 2.0. RAD-PAL was developed to target primary substance use and other challenging behaviors. Manhood 2.0 was developed to reduce traditional gender beliefs. These interventions have been adapted based on formative work with the target user group. PEGISUS will be embedded into existing vocational training programs and delivered by existing staff at these institutions.",[13],"Behavioral: PEGISUS",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care","NO_INTERVENTION","Standard of care is receiving the vocational training program that is offered through the partner organization and a healthcare referral for substance use. The vocational training programs are SOZO Foundation (South Africa), Build It International (Zambia), and Masvingo Polytechnic (Zimbabwe). SOZO Foundation offers training in six different vocational areas, including hairstyling, coding, and nutrition. They also teach life skills. Build It International offers construction programs and support beyond initial training through connection to employment and mentorship. Masvingo Polytechnic offers many programs, including electrical engineering, welding, guidance counseling, motor mechanics, and catering.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","PEGISUS is an 8-session intervention for substance use and gender equitable beliefs.",[9],[25],"Peer Education for Gender Inclusion and Substance Use in Southern Africa",[27],{"name":28,"affiliation":5,"role":29},"Jennifer M Belus, PhD","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Tara Carney","CONTACT","+27 21 938 0326","tara.carney@mrc.ac.za",[37,58,75],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"SOZO Foundation","RECRUITING","Cape Town","Western Cape","7975","South Africa","ZA",{"type":46,"coordinates":47},"Point",[48,49],18.42322,-33.92584,{"lat":49,"lon":48},[52,56],{"name":53,"role":33,"phone":54,"phoneExt":18,"email":55},"Thulani Ketelo","+27218255529","thulani@thesozofoundation.co.za",{"name":57,"role":29,"phone":18,"phoneExt":18,"email":18},"Tara Carney, PhD",{"facility":59,"status":39,"city":60,"state":18,"zip":18,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Build It International","Chibombo","Zambia","ZM",{"type":46,"coordinates":64},[65,66],28.07057,-14.65685,{"lat":66,"lon":65},[69,73],{"name":70,"role":33,"phone":71,"phoneExt":18,"email":72},"Chilufya Kasutu","+260211267715","c.kasutu@builditinternational.org",{"name":74,"role":29,"phone":18,"phoneExt":18,"email":18},"J. Anitha Menon, PhD",{"facility":76,"status":39,"city":77,"state":18,"zip":18,"country":78,"countryCode":79,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Masvingo Polytechnic","Masvingo","Zimbabwe","ZW",{"type":46,"coordinates":81},[82,83],30.82766,-20.06373,{"lat":83,"lon":82},[86,90],{"name":87,"role":33,"phone":88,"phoneExt":18,"email":89},"Bulisani Moyo","+26339253095","moyob@maspoly.ac.zw",{"name":91,"role":29,"phone":18,"phoneExt":18,"email":18},"Kudakwashe Madzeke, PhD",{"type":93,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[95,97,99],{"name":96,"class":6},"SolidarMed",{"name":98,"class":6},"University of Zambia",{"name":100,"class":6},"Medical Research Council, South Africa","100553731","peer-education-for-gender-inclusion-and-substance-use-in-southern-africa-100553731",false,"NCT06489899","Peer Education for Gender Inclusion and Substance Use in Southern Africa (PEGISUS): A Pilot Trial Testing a Peer-based Intervention in Vocational Training Programs","Inclusion Criteria:\n\n* Adolescents and young adults 16 - 24 years old\n* At least weekly self-reported alcohol\u002Fdrug use in a peer group in the past month or at least monthly heavy episodic drinking with peers over the past three months\n* Comfortable communicating in the predominant local language or English\n* Lives in the target community and plans to remain in the area for the next 12 months\n* Eligible to participate in the vocational training (VT) program (according to the VT program's own entry guidelines) and willing to participate in the entirety of the program\n* Interested to participate in a substance reduction and gender equity beliefs program and able to identify 2 to 5 peers to join\n* Willing to have PEGISUS workshop sessions audio\u002Fvideo-recorded (if assigned to that group)\n\nExclusion Criteria:\n\n* Untreated major mental illness that interferes with study participation, such as active suicidality, or unmanaged bipolar disorder or psychotic disorder\n* Currently receiving psychological treatment for substance use\n* Participation in another VT\u002Fskills development program or another trial that is judged by the site investigator as non-compatible with this study\n* Unable to provide informed consent or informed assent","ALL","16 Years","24 Years",{"count":111,"type":112},264,"ESTIMATED","INTERVENTIONAL",[115],"NA","The goal of this trial is to test the effectiveness of a brief, behavioral peer group intervention called \"PEGISUS\" (Peer Education for Gender Inclusion and Substance Use in Southern Africa), on substance use, which will be embedded within existing vocational training programs in Zambia, Zimbabwe, and South Africa. Established peer groups who receive the PEGISUS intervention will complete nine sessions of an adapted intervention for substance use and gender equitable beliefs, embedded into vocational training programs. This will be compared to a standard of care control condition, which involves the vocational training program that is offered through the partner organization and a healthcare referral for substance use. The vocational training program partners are Sozo Foundation (South Africa), BuildIt International (Zambia), and Masvingo Polytechnic (Zimbabwe). Participants in both conditions will complete assessments at baseline, 12-weeks follow-up, and 24-weeks follow-up, consisting of self-reported questionnaires.",[118,119],"Substance Use","Gender Role",[121,122,78,61,43],"gender","substance use","2025-09-16",{"date":125,"type":126},"2025-09-22","ACTUAL",{"date":128,"type":126},"2024-09-19",{"date":130,"type":112},"2026-07",{"name":5,"class":6},3]