[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566913":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":70,"collaborators":73,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":22,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":90,"enrollmentInfo":91,"targetDuration":12,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":106,"whyStopped":12,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Care Arm","NO_INTERVENTION","Participants randomized to the standard care arm will receive PrEP at a health facility from a physician or nurse.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"COMPrEP Intervention","EXPERIMENTAL","Participants randomized to the COMPrEP intervention will receive PrEP from peer lay workers at private community locations.",[18],"Behavioral: COMPrEP",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","COMPrEP","Participants will be paired with peer lay workers and will meet with peer lay workers at private community location. They will discuss options for oral PrEP with peer lay workers and be provided provide daily oral PrEP or event-driven (2-1-1) PrEP. Participants will take part in rapid HIV testing at each visit. They will also meet with peer lay workers at private community location for follow-up at 1, 5, 9, and 13 months.",[14],[26],{"name":27,"affiliation":28,"role":29},"Katia J Bruxvoort, PhD","University of Alabama at Birmingham School of Public Health","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":12,"email":34},"CONTACT","(205) 975-8625","kbruxvoort@uab.edu",{"name":36,"role":32,"phone":37,"phoneExt":12,"email":38},"Mallie E Froehlich, MSW","205-478-1102","mefroehl@uab.edu",[40,57],{"facility":41,"status":12,"city":42,"state":43,"zip":12,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Federal University of Bahia","Salvador","Estado de Bahia","Brazil","BR",{"type":47,"coordinates":48},"Point",[49,50],-38.49096,-12.97563,{"lat":50,"lon":49},[53],{"name":54,"role":32,"phone":55,"phoneExt":12,"email":56},"Ines Dourado, PhD, MD","+55 71 99975-4848","ines.dourado@gmail.com",{"facility":58,"status":12,"city":59,"state":59,"zip":12,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"University of São Paulo","São Paulo",{"type":47,"coordinates":61},[62,63],-46.63611,-23.5475,{"lat":63,"lon":62},[66],{"name":67,"role":32,"phone":68,"phoneExt":12,"email":69},"Alexandre Grangeiro","+55 11 98230-0600","ale.grangeiro@gmail.com",{"type":29,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Katia J. Bruxvoort","Principal Investigator",[74,77,79],{"name":75,"class":76},"National Institute of Mental Health (NIMH)","NIH",{"name":78,"class":6},"University of Sao Paulo",{"name":41,"class":6},"100566913","peer-led-community-based-prep-delivery-among-youth-in-brazil-100566913",false,"NCT06661356","Peer-led Community-based PrEP Delivery Among Youth in Brazil","Determining the Impact of Peer-led Community-based PrEP Delivery Among Youth in Brazil: A Randomized Controlled Trial","Eligibility Criteria:\n\n* Aged 15-24 years\n* Candidate for HIV prevention\n* Sexually active\n* Not currently using PrEP\n* Willing to discuss oral PrEP\n* Agree to be randomized to either intervention or standard care arm\n\nExclusion Criteria:\n\n* HIV positive test result\n* Not currently sexually active\n* Currently using PrEP",true,"ALL","15 Years","24 Years",{"count":92,"type":93},1400,"ESTIMATED","INTERVENTIONAL",[96],"NA","The goal of this project is to conduct a series of studies to refine, test, and understand experiences with a peer-led community-based intervention in which youth will be integrated into health care teams and trained to deliver HIV pre-exposure prophylaxis (PrEP) to their peers. The study team will conduct a randomized trial to determine if peer delivery of PrEP to youth aged 15-24 in Brazil will increase PrEP uptake, persistence, and adherence compared to standard PrEP care provided in health facilities.",[99,100],"Pre-Exposure Prophylaxis (PrEP)","HIV",[102,103,100,104,105],"PrEP","Pre-Exposure Prophylaxis","Peer lay workers","Youth","NOT_YET_RECRUITING","2026-03-03",{"date":109,"type":110},"2026-03-05","ACTUAL",{"date":112,"type":93},"2026-10",{"date":114,"type":93},"2029-08",{"name":5,"class":6},2]