[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514081":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":31,"locations":37,"responsibleParty":107,"collaborators":110,"id":117,"slug":118,"hasResults":119,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":119,"sex":125,"minAge":126,"maxAge":18,"enrollmentInfo":127,"targetDuration":18,"studyType":130,"phases":131,"briefSummary":133,"conditions":134,"keywords":140,"overallStatus":94,"whyStopped":18,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":153},{"fullName":5,"class":6},"University of Maryland, College Park","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Peer-Delivered Behavioral Activation (\"Peer Activate\")","EXPERIMENTAL","Participants in the Peer Activate intervention will receive a PRS-delivered behavioral activation intervention to address barriers to retention in methadone treatment and increase substance-free, positive reinforcement to support retention and reduce polysubstance use.",[13],"Behavioral: Peer-Delivered Behavioral Activation (\"Peer Activate\")",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment As Usual","NO_INTERVENTION","Participants in the TAU group will receive enhanced treatment as usual, defined as MTU services as usual enhanced with additional community referrals and follow-ups on those referrals, in addition to regular meetings with an addiction medicine physician and PRS on the MTU. Standard PRS contact typically includes connection to local resources and general peer support as needed.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","The PRS-delivered Peer Activate intervention will consist of approximately six weekly \"core\" sessions (approximately 30 minutes-1 hour), and then 6 optional \"booster\" sessions to reinforce skill practice. In Peer Activate sessions, participants will learn behavioral activation and problem-solving skills to reduce barriers to medication nonadherence and incorporate value-driven, substance-free, rewarding activities into their daily life to reduce polysubstance use and improve retention.",[9],[25,28],{"name":26,"affiliation":5,"role":27},"Jessica F Magidson, PhD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":27},"Sarah M Kattakuzhy, MD","University of Maryland, Baltimore",[32],{"name":33,"role":34,"phone":35,"phoneExt":18,"email":36},"Morgan S Anvari, BA","CONTACT","3014055095","manvari@umd.edu",[38,57,78,92],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"HIPS Clinic","NOT_YET_RECRUITING","Washington D.C.","District of Columbia","20002","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-77.03637,38.89511,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":55,"phoneExt":18,"email":56},"Sarah M. Kattakuzhy, MD","443-691-4638","skattakuzhy@ihv.umaryland.edu",{"facility":58,"status":40,"city":59,"state":60,"zip":61,"country":44,"countryCode":45,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"University of Maryland Baltimore (UMD Drug Treatment Center)","Baltimore","Maryland","21223",{"type":47,"coordinates":63},[64,65],-76.61219,39.29038,{"lat":65,"lon":64},[68,72,73,76],{"name":69,"role":34,"phone":70,"phoneExt":18,"email":71},"Heather Fitzsimons","443-462-3400","hfitzsimons@som.umaryland.edu",{"name":29,"role":27,"phone":18,"phoneExt":18,"email":18},{"name":74,"role":75,"phone":18,"phoneExt":18,"email":18},"Eric Weintraub, MD","SUB_INVESTIGATOR",{"name":77,"role":75,"phone":18,"phoneExt":18,"email":18},"Annabelle M Belcher, PhD",{"facility":5,"status":40,"city":79,"state":60,"zip":80,"country":44,"countryCode":45,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"College Park","20742",{"type":47,"coordinates":82},[83,84],-76.93692,38.98067,{"lat":84,"lon":83},[87,88,91],{"name":33,"role":34,"phone":35,"phoneExt":18,"email":36},{"name":26,"role":34,"phone":89,"phoneExt":18,"email":90},"301-405-5095","jmagidso@umd.edu",{"name":26,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":93,"status":94,"city":95,"state":60,"zip":96,"country":44,"countryCode":45,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Caroline County Behavioral Health","RECRUITING","Denton","21629",{"type":47,"coordinates":98},[99,100],-75.82716,38.88456,{"lat":100,"lon":99},[103],{"name":104,"role":34,"phone":105,"phoneExt":18,"email":106},"Jessica Tuel, MSW","410-479-8172","jessicam.tuel@maryland.gov",{"type":27,"investigatorFullName":108,"investigatorTitle":109,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Jessica Magidson","Director and Associate Professor",[111,112,114],{"name":30,"class":6},{"name":113,"class":6},"Weill Medical College of Cornell University",{"name":115,"class":116},"National Institute on Drug Abuse (NIDA)","NIH","100514081","peer-recovery-to-improve-polysubstance-use-and-mobile-telemedicine-retention-100514081",false,"NCT05973838","Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention","Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area","PRISM","Inclusion Criteria:\n\nPatient participants in the RCT must be 18 or older; receive OUD treatment as part of the telemedicine program; and exhibit polysubstance use within the past three-months (i.e., use of one or more non-prescribed substances (excluding opioids and\u002For tobacco) by urine toxicology or self-report.\n\nExclusion Criteria:\n\n* Demonstrating active, unstable or untreated psychiatric symptoms, including mania and\u002For psychosis that would interfere with study participation\n* Inability to understand the study and provide informed consent in English","ALL","18 Years",{"count":128,"type":129},160,"ESTIMATED","INTERVENTIONAL",[132],"NA","The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) and reduce polysubstance use among patients with OUD and polysubstance use in underserved areas. The intervention is based on behavioral activation (BA) and is specifically designed to be implemented by a trained peer recovery specialist. In this hybrid, Type-1 effectiveness-implementation randomized controlled trial (RCT), the investigators will evaluate the effectiveness and implementation of Peer Activate vs. treatment as usual (TAU) over twelve months.",[135,136,137,138,139],"Polysubstance Addiction","Opioid Medication Assisted Treatment","Treatment Adherence","Retention in Care","Substance-Related Disorders",[139,141,142,143],"Opioid-Related Disorders","Polysubstance Use","Mental disorders","2026-04-21",{"date":146,"type":147},"2026-04-27","ACTUAL",{"date":149,"type":147},"2023-06-15",{"date":151,"type":129},"2027-09-01",{"name":5,"class":6},4]