[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530306":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":24,"responsibleParty":39,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"University Medical Center Goettingen","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"oART",null,"Patients with pelvic or thoracic tumors with an indication for radiotherapy treated with oART (online Adaptied Radiotherapy).",{"label":13,"type":10,"description":14,"interventionNames":10},"IGRT","Patients with pelvic or thoracic tumors with an indication for radiotherapy treated with conventional IGRT (Image Guided Radiotherapy).",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Laura Anna Fischer","CONTACT","+49 551 3964501","laura-anna.fischer@med.uni-goettingen.de",{"name":22,"role":18,"phone":10,"phoneExt":10,"email":23},"Rami El Shafie","rami.elshafie@med.uni-goettingen.de",[25],{"facility":26,"status":27,"city":28,"state":10,"zip":10,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"University Medical Center, Departement of Radiation Oncology","RECRUITING","Göttingen","Germany","DE",{"type":32,"coordinates":33},"Point",[34,35],9.93228,51.53443,{"lat":35,"lon":34},[38],{"name":17,"role":18,"phone":10,"phoneExt":10,"email":20},{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Prof. Dr. Rami El Shafie","Clinical Study Management on behalf of the Principal Investigator","100530306","pelvic-cancer-registry-for-online-adapted-radiotherapy-100530306",false,"NCT06185062","Pelvic Cancer Registry for Online Adapted Radiotherapy","Pelvic and Thoracic Cancer Treated With Online Adapted Radiotherapy: A Prospective Registry-based Phase-II Trial","PRoART","INCLUSION CRITERIA\n\n* Patients with pelvic or thoracic tumors with an indication for radiotherapy\n* Patient information and declaration of consent\n* Patients age ≥ 18 years\n\nEXCLUSION CRITERIA\n\n* Prior radiotherapy in affected site","ALL","18 Years",{"count":54,"type":55},846,"ESTIMATED","5 Years","OBSERVATIONAL","This prospective registry-based trial will include patients with pelvic or thoracic tumors with an indication for radiotherapy treated with oART or IGRT. For the primary endpoint and the secondary clinical endpoints, the trial will compare oART versus IGRT, for technical endpoints the trial will compare the real oART scenario with two virtual (hypothetical) control scenarios.\n\nPrimary endpoint:\n\n* 10% reduction in the rate of acute radiotherapy related toxicity (≥ CTCAE II°, v5.0) using oART\n\nSecondary endpoints:\n\n* Clinical endpoints: Tumor control, late toxicities compared to conventional irradiated patients, quality of life and patient-reported outcomes\n* Technical endpoints: Target volume, target coverage, dose to organs at risk, anatomical variability score",[60,61],"Pelvic Tumor","Thoracic Tumor",[63],"online Adaptive Radiotherapy","2024-02-06",{"date":66,"type":67},"2024-02-08","ACTUAL",{"date":69,"type":67},"2024-01-01",{"date":71,"type":55},"2030-04",{"name":5,"class":6},1]