[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596483":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University College Cork","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Continuous PENG Infusion","ACTIVE_COMPARATOR","Participants will be randomly assigned to this arm and will receive a continuous infusion of levobupivacaine.",[13],"Other: continuous infusion of levobupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Programmed Intermittent Bolus PENG","EXPERIMENTAL","Participants will be randomly assigned to this arm and will receive a timed pre-set bolus dose of levobupivacaine.",[19],"Other: Programmed Intermittent Bolus of Levobupivacaine",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"continuous infusion of levobupivacaine","Participants in this arm will receive a continuous infusion of levobupivacaine via a regional anaesthesia catheter placed in the PENG fascial space. The total dose over 24 hours will be equivalent in both arms of the study.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Programmed Intermittent Bolus of Levobupivacaine","Participants in this arm will receive a timed pre-set bolus dose of levobupivacaine via a regional anaesthesia catheter placed in the PENG fascial space. The total dose over 24 hours will be equivalent in both groups.",[15],[31],{"name":32,"affiliation":33,"role":34},"Benjamin P Atterton, MBChB FRCA","Cork University Hospital & University College Cork","STUDY_DIRECTOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Brian D O'Donnell, MBBChBAO MSc FCARCSI MD","CONTACT","+353872780225","briodnl@gmail.com",[42],{"facility":43,"status":44,"city":45,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Cork University Hospital","RECRUITING","Cork","P85 FR62","Ireland","IE",{"type":50,"coordinates":51},"Point",[52,53],-8.47061,51.89797,{"lat":53,"lon":52},[56,57],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},{"name":32,"role":58,"phone":25,"phoneExt":25,"email":25},"SUB_INVESTIGATOR",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Brian Declan O'Donnell","Consultant Anaesthesiologist","100596483","peng-block-continuous-infusion-vs-programmed-intermittent-bolus-in-neck-of-femur-fracture-100596483",false,"NCT07046052","PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture","A Double Blind Randomised Controlled Trial Comparing Continuous Infusion vs. Programmed Intermittent Bolus Via a Pericapsular Nerve Group (PENG) Catheter for Post Operative Fractured Neck of Femur Analgesia","Inclusion Criteria:\n\n* English-speaking\n* over the age of 18 years\n* hemiarthroplasty for fractured neck of femur\n* able to provide written consent.\n\nExclusion Criteria:\n\n* under 50kg body weight.\n* unable to provide consent due to incapacity\n* pregnant women\n* vulnerable adults under state guardianship\n* Patients with pre-existing chronic pain disorders or with a history of long-term opioid use\n* those with contraindications to a peripheral nerve block such as local site infection, allergy to local anaesthetic or those who are coagulopathic","ALL","18 Years",{"count":73,"type":74},150,"ESTIMATED","INTERVENTIONAL",[77],"NA","Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture. Continuous PENG techniques, using indwelling catheters and infusions of local anaesthetic, facilitate the continuation of analgesia for a number of days following hip fracture surgery. It is unclear from the published literature whether an optimal strategy of local anaesthetic delivery has been characterized.\n\nSimilar doses of local anaesthetic agents can be administered by either continuous infusion or timed intermittent bolus. It is unclear whether one dosing strategy is superior to the other in the context of hip fracture analgesia. The study aims to evaluate the clinical efficacy of both dosing strategies in patients undergoing hip fracture surgery.",[80,81],"Hip Fracture","Analgesia Post Fracture",[83,84,85,86,87,88,89],"hip fracture","regional anaesthesia","analgesia","peng block","continuous infusion","programmed intermittent bolus","randomised controlled trial","2025-06-22",{"date":92,"type":93},"2025-07-01","ACTUAL",{"date":95,"type":93},"2024-03-28",{"date":97,"type":74},"2026-01-07",{"name":5,"class":6},1]