[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618151":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":48,"responsibleParty":64,"collaborators":46,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":46,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":46,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":46,"overallStatus":50,"whyStopped":46,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Poznan University of Medical Sciences","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"PENG Block","ACTIVE_COMPARATOR","Participants will receive an ultrasound-guided pericapsular nerve group (PENG) block administered as a single perineural injection prior to surgery, using a standardized technique.",[13],"Procedure: Pericapsular Nerve Group (PENG) Block",{"label":15,"type":16,"description":17,"interventionNames":18},"PENG Block Plus Periarticular Injection (PAI)","EXPERIMENTAL","Participants will receive an ultrasound-guided PENG block (single perineural injection prior to surgery) plus a periarticular injection administered intraoperatively by the surgeon according to a standardized protocol.",[13,19],"Procedure: Periarticular Injection (PAI)",{"label":21,"type":10,"description":22,"interventionNames":23},"Periarticular Injection (PAI) Alone","Participants will receive a periarticular injection administered intraoperatively by the surgeon according to a standardized protocol, without a PENG block.",[19],[25,32],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Pericapsular Nerve Group (PENG) Block","Ultrasound-guided regional anesthesia technique targeting sensory innervation of the anterior hip capsule, performed as a single injection prior to surgery using a standardized protocol.",[9,15],[31],"Ultrasound-guided PENG block",{"type":26,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Periarticular Injection (PAI)","Intraoperative periarticular injection performed by the surgeon according to a standardized institutional protocol as part of postoperative pain management.",[15,21],[37],"Local infiltration analgesia; periarticular local anesthetic injection",[39],{"name":40,"affiliation":5,"role":41},"Malgorzata Reysner, MD PhD","STUDY_CHAIR",[43],{"name":40,"role":44,"phone":45,"phoneExt":46,"email":47},"CONTACT","+48 61 873 83 03",null,"mreysner@ump.edu.pl",[49],{"facility":5,"status":50,"city":51,"state":46,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Poznan","62-701","Poland","PL",{"type":56,"coordinates":57},"Point",[58,59],16.92993,52.40692,{"lat":59,"lon":58},[62],{"name":63,"role":44,"phone":45,"phoneExt":46,"email":47},"Malgorzata Reysner, M.D. Ph.D.",{"type":65,"investigatorFullName":46,"investigatorTitle":46,"investigatorAffiliation":46,"oldNameTitle":46,"oldOrganization":46},"SPONSOR","100618151","peng-block-vs-peng-plus-periarticular-injection-vs-periarticular-injection-in-older-adults-100618151",false,"NCT07327892","PENG Block vs PENG Plus Periarticular Injection vs Periarticular Injection in Older Adults","Comparison of Pericapsular Nerve Group (PENG) Block, PENG Block Plus Periarticular Injection, and Periarticular Injection Alone for Postoperative Pain Management in Older Adults Undergoing Hip Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 65 years or older\n* Scheduled for elective or emergency hip surgery (e.g., hip fracture fixation or hip arthroplasty)\n* ASA physical status I-III\n* Ability to communicate pain intensity using the NRS scale\n* Written informed consent obtained from the patient or legal representative\n\nExclusion Criteria:\n\n* Patient refusal or inability to provide informed consent\n* Allergy, intolerance, or contraindication to any study medication: ropivacaine\n* Pre-existing neurological deficit or neuropathy of the affected limb\n* Coagulopathy (INR \\>1.5, platelets \\\u003C100,000\u002FµL) or current therapeutic anticoagulation that contraindicates regional anesthesia\n* Infection at or near the injection site\n* Severe hepatic or renal impairment\n* History of chronic opioid use (daily opioids \\>30 days before surgery)\n* Cognitive impairment or delirium precluding reliable pain assessment\n* BMI \\> 40 kg\u002Fm² (if you want to exclude for technical difficulty)\n* Patients receiving another regional nerve block for hip surgery\n* Pregnancy or breastfeeding\n* Participation in another interventional clinical trial within 30 days","ALL","65 Years","100 Years",{"count":77,"type":78},108,"ESTIMATED","INTERVENTIONAL",[81],"NA","Pain after hip surgery is common in older adults and may limit early mobilization, increase the need for opioid medications, and contribute to complications such as delirium, nausea, or prolonged hospital stay. Effective postoperative pain management that preserves muscle strength and supports early rehabilitation is especially important in this population.\n\nSeveral analgesic strategies are currently used after hip surgery. Periarticular injection (PAI), administered by the surgeon during the procedure, is commonly used as part of standard care. The pericapsular nerve group (PENG) block is a newer ultrasound-guided regional anesthesia technique that targets the sensory nerves of the hip joint while sparing motor function. It may provide effective pain relief and facilitate early mobilization. However, it is unclear whether PENG block alone is superior to periarticular injection, and whether combining both techniques provides additional benefit.\n\nThe aim of this randomized controlled clinical study is to compare three postoperative analgesic strategies in older adults undergoing hip surgery: PENG block alone, PENG block combined with periarticular injection, and periarticular injection alone. Participants will be randomly assigned to one of three study groups.\n\nThe primary hypothesis is that regional anesthesia with a PENG block, either alone or combined with periarticular injection, will provide superior postoperative pain control compared with periarticular injection alone. A secondary hypothesis is that the combination of PENG block and periarticular injection will offer additional analgesic benefit compared with PENG block alone.\n\nOutcomes assessed in this study will include postoperative pain intensity, need for additional pain medications, time to first mobilization, and the occurrence of adverse events relevant to older adults, such as hypotension, excessive sedation, or postoperative delirium.\n\nThe results of this study may help determine the most effective and practical analgesic strategy for hip surgery in older adults and support evidence-based optimization of postoperative pain management.",[84,85],"Hip Osteoarthritis","Arthropathy of Hip","2026-06-29",{"date":88,"type":89},"2026-07-01","ACTUAL",{"date":91,"type":89},"2026-05-08",{"date":93,"type":78},"2027-02-28",{"name":5,"class":6},1]