[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100248889":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":35,"centralContacts":47,"locations":54,"responsibleParty":74,"collaborators":35,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":35,"enrollmentInfo":88,"targetDuration":35,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":35,"overallStatus":56,"whyStopped":35,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Per oral endoscopic therapy A","ACTIVE_COMPARATOR","Per oral endoscopic myotomy",[13],"Procedure: Endoscopic intervention A",{"label":15,"type":10,"description":16,"interventionNames":17},"Per oral endoscopic therapy B","Prolonged dilatation by implantation of large diameter stents.",[18],"Procedure: Endoscopic intervention B",{"label":20,"type":10,"description":21,"interventionNames":22},"Per oral endoscopic therapy C","Dilatation",[23],"Procedure: Endoscopic intervention C",{"label":25,"type":10,"description":26,"interventionNames":27},"Laparoscopic surgery","Laparoscopic Heller myotomy",[28],"Procedure: Laparoscopic Surgery",[30,36,40,44],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"PROCEDURE","Endoscopic intervention A","POEM: Per oral endoscopic myotomy",[9],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Endoscopic intervention B","PRD: Prolonged dilatation by temporary implantation of large diameter stent . Stents are additionally attached to the esophageal wall by different technical options.",[15],{"type":31,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"Endoscopic intervention C","Endoscopic balloon dilatation",[20],{"type":31,"name":45,"description":26,"armGroupLabels":46,"otherNames":35},"Laparoscopic Surgery",[25],[48],{"name":49,"role":50,"phone":51,"phoneExt":52,"email":53},"Department of Surgery, Medical University of Vienna","CONTACT","+43 1 40400","5621","sebastian.schoppmann@meduniwien.ac.at; erwin.rieder@meduniwien.ac.at",[55],{"facility":49,"status":56,"city":57,"state":35,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"RECRUITING","Vienna","1090","Austria","AT",{"type":62,"coordinates":63},"Point",[64,65],16.37208,48.20849,{"lat":65,"lon":64},[68,71],{"name":69,"role":50,"phone":51,"phoneExt":52,"email":70},"Sebastian F Schoppmann, MD","sebastian.schoppmann@meduniwien.ac.at",{"name":72,"role":50,"phone":51,"phoneExt":52,"email":73},"Erwin Rieder, MD","erwin.rieder@meduniwien.ac.at",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Erwin Rieder","Priv. Doz. Dr. Erwin Rieder","100248889","per-oral-endoscopic-myotomy-poem-and-prolonged-dilatation-prd-for-achalasia-100248889",false,"NCT02518542","Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) for Achalasia","Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) as Additional Endoscopic Treatment Options for Achalasia and Other Esophageal Motility Disorders","POETA","Inclusion Criteria:\n\n* Confirmed diagnosis of achalsia, hypertensive lower esophageal sphincter, nutcracker esophagus, or diffuse esophageal spasm\n\nExclusion Criteria:\n\n* Contraindication for EGD","ALL","18 Years",{"count":89,"type":90},400,"ESTIMATED","INTERVENTIONAL",[93],"NA","Achalasia is an esophageal motility disorder, which leads to clinical symptoms such as dysphagia, regurgitation, chest pain and consecutive weight loss.\n\nAlthough conventional treatment such as laparoscopic Heller myotomy (LHM) and balloon dilatation (BD) can provide sufficient symptom relief in many patients, both interventions have their individual drawbacks. Additionally, treatment after failed LHM or BD can be challenging and in few might even lead to esophagectomy.\n\nPer oral endoscopic myotomy (POEM) and prolonged dilatation (PRD) are two novel endoscopically performed therapeutic options for achalasia and other esophageal motility disorders. Both not only appear to provide good results, when performed as initial treatment but also might be an excellent option after e.g failed LHM.\n\nThe purpose of this study is to evaluate the long-term efficacy of four different treatment options, such as POEM, PRD with stent-fixation, PD and conventional LHM for achalasia in an individualized treatment setting.",[96],"Esophageal Achalasia","2015-08-07",{"date":99,"type":90},"2015-08-10",{"date":101,"type":35},"2014-06",{"date":103,"type":90},"2027-06",{"name":5,"class":6},1]